Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zachary Knotts"'
Autor:
Raul Calvo, Noel Southall, Lixin Fan, Chan Young Ock, Keyur Talsania, Clayton Yates, Taylor Aiken, Yansong Bian, Zachary Knotts, Yongmei Zhao, Jesse M. Jaynes, Jason White, Abisola Abisoye-Ogunniyan, Taivan Odzorig, Anghesom Ghebremedhin, Myagmarjav Dashnyam, Anton Simeonov, Sarangan Ravichandran, Nathan Pate, Amber E. de Groot, Michael Ronzetti, Xin Hu, Vicky Chen, Jelani C. Zarif, Henry Lopez, Bolormaa Baljinnyam, Parimal Kumar, Dandan Li, Natalia de Val, Theresa Guerin, Wendy Bautista, Ahmad Bin Salam, Rushikesh Sable, Juan J. Marugan, Marc Ferrer, Serguei Kozlov, Victoria Nguyen, Monika Mehta, Balasubramanyam Karanam, Ruksana Amin, Mones Abu-Asab, Udo Rudloff, Anju Singh
Publikováno v:
Sci Transl Med
Solid tumors elicit a detectable immune response including the infiltration of tumor-associated macrophages (TAMs). Unfortunately, this immune response is co-opted into contributing toward tumor growth instead of preventing its progression. We seek t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513d18826af0875f5379d90cda6894d2
https://doi.org/10.1126/scitranslmed.aax6337
https://doi.org/10.1126/scitranslmed.aax6337
Autor:
Juan J. Marugan, Samarjit Patnaik, Udo Rudloff, Noel Southall, Debra Gilbert, Sui Huang, Chen Wang, Zachary Knotts, Christopher R. Dextras, Amy Wang, Stephanie Springer, Serguei Kozlov, Catherine Drennan, Marc Ferrer, Tomas Vilimas, Theresa Guerin, Kevin J. Frankowski, Jerome J. Schlomer, Emma Hughes, Marc D. Singleton, Xin Xu, Dandan Li
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Metarrestin is a first-in-class small molecule clinical candidate capable of disrupting the perinucleolar compartment, a subnuclear structure unique to metastatic cancer cells. This study aims to define the pharmacokinetic (PK) profile of met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d846354317011e8cfcff4ac8dd67942
http://europepmc.org/articles/PMC6267684
http://europepmc.org/articles/PMC6267684
Autor:
Abisola Abisoye-Ogunniyan, Jesse M. Jaynes, Clayton Yates, Xia Xu, Zachary Knotts, Theresa Guerin, Jerome J. Schlomer, King C. Chan, Dandan Li, Jeffrey W. Cary, Serguei Kozlov, Maura O'Neill, Kanniah Rajasekaran, Udo Rudloff, Thorkell Andresson
Publikováno v:
J Pharm Biomed Anal
Synthetic host defense peptides (HDP) are a new class of promising therapeutic agents with potential application in a variety of diseases. RP-182 is a 10mer synthetic HDP design, which selectively reduces M2-like tumor associated macrophages via enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938fcbc4f86032c318722258362b7041
https://doi.org/10.1016/j.jpba.2020.113093
https://doi.org/10.1016/j.jpba.2020.113093
Autor:
Zachary Knotts, Susan J. Baserga, Eric Chow, Dandan Li, Udo Rudloff, Samarjit Patnaik, Warren Chen, Charles Long, Frank J. Schoenen, Wei Zheng, Steve Titus, Ming Zhou, Zhaojing Meng, Tomas Vilimas, Yiping Wen, Lesley A. Mathews Griner, Irawati Kandela, Yansong Bian, Marzena Anna Lewandowska, Jinsol Kang, Helen Huang, Jamey Sultan, Christopher R. Dextras, Ojus Khanolkar, Noel Southall, Jeffrey Aubé, John Norton, G. Gary Sahagian, Marc Ferrer, Esthermanya Goldberg, Ali Shilatifard, Kevin J. Frankowski, Min Fang, Katherine I. Farley, Sui Huang, Chen Wang, Yaroslav Teper, Romi Xi, Coral Feldman, Humair S. Quadri, Wei Sun, Juan J. Marugan, Kunio Nagashima, Andrew P. Mazar, Deqing Hu, Hyerim Kim, Astin Powers, Serguei Kozlov
Metastasis remains a leading cause of cancer mortality due to the lack of specific inhibitors against this complex process. To identify compounds selectively targeting the metastatic state, we used the perinucleolar compartment (PNC), a complex nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408d52fb0bfe03039b0f762fbf8f8109
https://europepmc.org/articles/PMC6176865/
https://europepmc.org/articles/PMC6176865/
Autor:
Humair S. Quadri, R. Xi, Y. Bian, Noel Southall, Y. Wen, Juan J. Marugan, Serguei Kozlov, Jeffrey Aubé, Andrew P. Mazar, W. Chen, Christopher R. Dextras, M. Zhou, Astin Powers, E. Chow, Steve Titus, H. R. Kim, H. Huang, W. Zheng, Jamey Sultan, C. Wang, Kevin J. Frankowski, M. Fang, D. Hu, E. Goldberg, Marzena Anna Lewandowska, Irawati Kandela, Frank J. Schoenen, Susan J. Baserga, Samarjit Patnaik, C. Long, Marc Ferrer, G. Gary Sahagian, Z. Meng, Udo Rudloff, W. Sun, J. Kang, O. Khanolkar, Lesley A. Mathews Griner, D. Li, Zachary Knotts, John Norton, Katherine I. Farley, Ali Shilatifard, Yaroslav Teper, Tomas Vilimas, S. Huang, Kunio Nagashima, C. Feldman
Publikováno v:
Biopolymers and Cell. 35:193-193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::977f2cfdbfe4344a9d66e673f667e55e
https://doi.org/10.7124/bc.0009c9
https://doi.org/10.7124/bc.0009c9