Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zachary K. Ford"'
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Cannabinoid receptors have been identified as potential targets for analgesia from studies on animal physiology and behavior, and from human clinical trials. Here, we sought to improve translational understanding of the mechanisms of cannabinoid-medi
Externí odkaz:
https://doaj.org/article/3ac35d44880a441bbd55fbb7a9d55a1a
Autor:
Zachary K. Ford, Adam J. Dourson, Xiaohua Liu, Peilin Lu, Kathryn J. Green, Renita C. Hudgins, Michael P. Jankowski
Publikováno v:
IBRO Reports, Vol 6, Iss , Pp 111-121 (2019)
Injury during early postnatal life causes acute alterations in afferent function and DRG gene expression, which in addition to producing short-term sensitivity has the potential to influence nociceptive responses in adulthood. We recently discovered
Externí odkaz:
https://doaj.org/article/fbe918ec375840c99ee260460f6bf6bb
Autor:
Yonghui Zhao, Hongzhen Hu, Changxiong J. Guo, Oshri Avraham, Aaron M. Ver Heul, Jing Feng, Asima Badic, Dean W. Coble, Jennifer Alexander-Brett, Brian S. Kim, Masato Kubo, Zachary K. Ford, Masato Tamari, Satoru Joshita, Landon K. Oetjen, Carina Dehner, Steve Davidson, Anna M. Trier, Avery Fredman, Madison R. Mack, Valeria Cavalli, Robert W. Gereau, Qin Liu
Publikováno v:
J Allergy Clin Immunol
Background Chronic pruritus, or itch, is common and debilitating, but the neuroimmune mechanisms that drive chronic itch are only starting to be elucidated. Recent studies demonstrate that the IL-33 receptor (IL-33R) is expressed by sensory neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fc16774cfd88db5ee2f11812d52786
https://europepmc.org/articles/PMC8934751/
https://europepmc.org/articles/PMC8934751/
Autor:
Xiaohua Liu, Kathryn J. Green, Renita C. Hudgins, Michael P. Jankowski, Peilin Lu, Adam J. Dourson, Zachary K. Ford
Publikováno v:
IBRO Reports, Vol 6, Iss, Pp 111-121 (2019)
IBRO Reports
IBRO Reports
Highlights • Systemic GHD causes behavioral hypersensitivity at P7 and P14, but not P21. • Primary afferent sensitization is observed in GHRHr KOs. • Knockout of GHRHr changes DRG gene expression that is observed throughout development.
In
In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c654b4a30cba9021ed2ad3e651de5b
http://www.sciencedirect.com/science/article/pii/S2451830119300020
http://www.sciencedirect.com/science/article/pii/S2451830119300020
Autor:
Renita C. Hudgins, Aaron T. Shank, Peilin Lu, Xiaohua Liu, Kathryn J. Green, Frank B Lee, Zachary K. Ford, Jessica L. Ross, Luis F. Queme, Michael P. Jankowski
Publikováno v:
Pain. 158(2)
Cutaneous inflammation alters the function of primary afferents and gene expression in the affected dorsal root ganglia (DRG). However, specific mechanisms of injury-induced peripheral afferent sensitization and behavioral hypersensitivity during dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdefa511a7c30738aa4bbad7accff38
https://pubmed.ncbi.nlm.nih.gov/28514789
https://pubmed.ncbi.nlm.nih.gov/28514789
Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination
Autor:
Brian Ayee, Michael P. Jankowski, Chuntao Zhao, Liguo Zhang, Jincheng Wang, Zachary K. Ford, Q. Richard Lu, An Zwijsen, Haibo Wang, Patrice Maurel, Christiane Zweier, Danny Huylebroeck, Andrea Conidi, Lai Man Natalie Wu, Jonah R. Chan
Publikováno v:
Nature Neuroscience, 19(8), 1060-+. Nature Publishing Group
Nature neuroscience
Nature neuroscience
The mechanisms that coordinate and balance a complex network of opposing regulators to control Schwann cell (SC) differentiation remain elusive. Here we demonstrate that zinc-finger E-box-binding homeobox 2 (Zeb2, also called Sip1) transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3dab7449cf72f933a581a744186fd9
https://pure.eur.nl/en/publications/33b95ae2-7a08-4944-9df6-38896a5108b5
https://pure.eur.nl/en/publications/33b95ae2-7a08-4944-9df6-38896a5108b5
Autor:
Xiaohua Liu, Megan C. Hofmann, Luis F. Queme, Peilin Lu, Zachary K. Ford, Renita C. Hudgins, Michael P. Jankowski
Publikováno v:
Molecular Pain
The upregulation of various channels and receptors classically linked to sensory transduction from the periphery tightly correspond with changes in the responsiveness of specific subpopulations of primary afferents to mechanical and heat stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d463292d801d4f01163da398d96fd7b7
https://doi.org/10.1177/1744806917730255
https://doi.org/10.1177/1744806917730255