Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zachary K. Englander"'
Autor:
Zachary K. Englander, Hong-Jian Wei, Antonios N. Pouliopoulos, Ethan Bendau, Pavan Upadhyayula, Chia-Ing Jan, Eleanora F. Spinazzi, Nina Yoh, Masih Tazhibi, Nicholas M. McQuillan, Tony J. C. Wang, Jeffrey N. Bruce, Peter Canoll, Neil A. Feldstein, Stergios Zacharoulis, Elisa E. Konofagou, Cheng-Chia Wu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Drug delivery in diffuse intrinsic pontine glioma is significantly limited by the blood-brain barrier (BBB). Focused ultrasound (FUS), when combined with the administration of microbubbles can effectively open the BBB permitting the entry of
Externí odkaz:
https://doaj.org/article/e7a089d62acc48338378a525c21513c4
Autor:
Binsheng Zhao, Peter Canoll, Jonathan Yun, Alexander Romanov, Xiaotao Guo, Timothy H. Ung, Jeffrey N. Bruce, Justin A. Neira, Matei A. Banu, Benjamin C. Kennedy, Nikita G. Alexiades, Randy S. D'Amico, Zachary K. Englander, Adam M. Sonabend, Robert J Rothrock
Publikováno v:
J Neurosurg
OBJECTIVEIntracerebral convection-enhanced delivery (CED) has been limited to short durations due to a reliance on externalized catheters. Preclinical studies investigating topotecan (TPT) CED for glioma have suggested that prolonged infusion improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a82b0b1b49ef376813912ddf282509c
https://doi.org/10.3171/2019.3.jns1963
https://doi.org/10.3171/2019.3.jns1963
Autor:
Nicholas McQuillan, Antonios N. Pouliopoulos, Stergios Zacharoulis, Hong-Jian Wei, Ethan Bendau, Elisa E. Konofagou, Zachary K. Englander, Andrea Webster, Nina Yoh, Masih Tazhibi, Cheng-Chia Wu
Publikováno v:
Neuro Oncol
Diffuse midline gliomas (DMG) are pediatric tumors with dismal prognosis. When these tumors emerge in the brainstem, there exists no feasible method of surgical resection or systemic intervention, making ionizing radiation the sole therapeutic avenue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4c1009dd76d6db08cb7d80cc577fc
https://europepmc.org/articles/PMC8598601/
https://europepmc.org/articles/PMC8598601/
Autor:
Elisa E. Konofagou, Zachary K. Englander, Noé Jiménez, Stergios Zacharoulis, Antonios N. Pouliopoulos, Cheng-Chia Wu, Sergio Jiménez-Gambín, Francisco Camarena
Publikováno v:
2021 IEEE International Ultrasonics Symposium (IUS).
Targeted drug delivery to enhance chemotherapy treatments in brain tumors can be achieved by opening the blood-brain barrier in a non-invasive, transient, localized, safe manner by using focused ultrasound (FUS) and microbubbles. However, as brain tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac4c022f60d7b67eeae79c1fae7e5de
https://doi.org/10.1109/ius52206.2021.9593797
https://doi.org/10.1109/ius52206.2021.9593797
Autor:
Stergios Zacharoulis, Cheng-Chia Wu, Antonios N. Pouliopoulos, Neil A. Feldstein, Elisa E. Konofagou, Zachary K. Englander, Nina Yoh, Jeffrey N. Bruce, Tony J. C. Wang, Hong-Jian Wei, Masih Tazhibi, Peter Canoll, Nicholas McQuillan
Publikováno v:
Neuro-Oncology
Background Diffuse intrinsic pontine glioma (DIPG) is a devastating pediatric brain cancer with limited treatment options and poor survival. The delivery of systemic therapies in this disease is severely limited by the blood-brain barrier (BBB). Focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f1965eb36a68f0e81410a0f5cb19c2
http://europepmc.org/articles/PMC8263168
http://europepmc.org/articles/PMC8263168
Autor:
Angeliki Mela, Tony J. C. Wang, Xu Zhang, Jeffrey N. Bruce, Pavan S. Upadhyayula, Elisa E. Konofagou, Peter Canoll, Zachary K. Englander, Antonios N. Pouliopoulos, Cheng-Chia Wu, Hong-Jian Wei, Chia-Ing Jan, Stergios Zacharoulis, Neil A. Feldstein, Jia Guo, Zhiguo Zhang
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Glioblastoma (GBM) is a devastating disease. With the current treatment of surgery followed by chemoradiation, outcomes remain poor, with median survival of only 15 months and a 5-year survival rate of 6.8%. A challenge in treating GBM is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ede9f9c41859fde6a2943d6521ffb8
https://pubmed.ncbi.nlm.nih.gov/33346092
https://pubmed.ncbi.nlm.nih.gov/33346092
Autor:
Peter Chang, Stephen G Bowden, George Zanazzi, Jeffrey N. Bruce, Craig I Horenstein, Jack Grinband, Brian J A Gill, Peter Canoll, Jorge Samanamud, Zachary K. Englander, Angela Lignelli
Publikováno v:
American Journal of Neuroradiology. 39:507-514
BACKGROUND AND PURPOSE: Malignant glioma is a highly infiltrative malignancy that causes variable disruptions to the structure and function of the cerebrovasculature. While many of these structural disruptions have known correlative histopathologic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e737221712f55fb97e9a291d084a1b78
https://doi.org/10.3174/ajnr.a5526
https://doi.org/10.3174/ajnr.a5526
Autor:
Dominic Higgins, Alexis B. Maddocks, James Garvin, Rebecca J. Zylber, Jeffrey N. Bruce, Peter Canoll, Neil A. Feldstein, Eileen Stark, Chankrit Sethi, Stergios Zacharoulis, Zachary K. Englander, Steve Dammnett, Craig Cook, ZhenZhen Jin, Luca Szalontay
Publikováno v:
Neuro-Oncology
Convection-enhanced delivery (CED, the infusion of drugs under controlled pressure to the brain parenchyma via targeted micro-catheters, allows accurate anatomical targeting and delivery of higher (therapeutic) drug concentrations through clinically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc45c83ef99a300751a0afa7b99c5fe7
http://europepmc.org/articles/PMC7715104
http://europepmc.org/articles/PMC7715104
Autor:
Moshe Praver, Neil A. Feldstein, Jorge Samanamud, Peter Canoll, Jeffrey N. Bruce, Guy M. McKhann, Alfred T. Ogden, Jennifer S. Sims, George Zanazzi, Paul C. Mccormick, Michael B. Sisti, Zachary K. Englander, Randy S. D'Amico
Publikováno v:
World Neurosurgery. 107:451-463
Objective Subependymomas are infrequent, low-grade gliomas associated with the ventricular system and the spinal cord. Little is known about the origin and natural history of these slow-growing lesions. Methods We identified all patients with patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8f88e0b1699848df9510dea6b5b8c9
https://doi.org/10.1016/j.wneu.2017.08.009
https://doi.org/10.1016/j.wneu.2017.08.009
Autor:
Peter Canoll, George Zanazzi, Jeffrey N. Bruce, Stephen G Bowden, Randy S. D'Amico, Zachary K. Englander, Brian J A Gill, Jorge Samanamud, Jack Grinband, Timothy H. Ung, Guy M. McKhann, Sameer A. Sheth, Michael B. Sisti, Justin A. Neira, Peter Chang
Publikováno v:
Neurosurgery. 82:719-727
BACKGROUND Accurate tissue sampling in nonenhancing (NE) gliomas is a unique surgical challenge due to their intratumoral histological heterogeneity and absence of contrast enhancement as a guide for intraoperative stereotactic guidance. Instead, T2/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa0e1ca7890a5e9d9e3c9ad2439d15b
https://doi.org/10.1093/neuros/nyx271
https://doi.org/10.1093/neuros/nyx271