Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zachary K. Boswell"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract The Mre11-Rad50 protein complex is an initial responder to sites of DNA double strand breaks. Many studies have shown that ATP binding to Rad50 causes global changes to the Mre11-Rad50 structure, which are important for DNA repair functions.
Externí odkaz:
https://doaj.org/article/9483ddab1c2f42be85f632a0db182db5
Publikováno v:
Nucleic Acids Research
DNA damage is the driving force for mutation and genomic instability, which can both lead to cell death or carcinogenesis. DNA double strand breaks are detected and processed in part by the Mre11–Rad50–Nbs1 protein complex. Although the Mre11–R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba18bcfe1e4ff84a99d2a3021bb72235
https://doi.org/10.1093/nar/gkz1228
https://doi.org/10.1093/nar/gkz1228
Autor:
Zachary K. Boswell, Michael P. Latham
Publikováno v:
Biochemistry. 58:144-155
NMR spectroscopy is particularly adept at site-specifically monitoring dynamic processes in proteins, such as protein folding, domain movements, ligand binding, and side-chain rotations. By coupling the favorable spectroscopic properties of highly dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea449e42ce535234792017b30329202
https://doi.org/10.1021/acs.biochem.8b00953
https://doi.org/10.1021/acs.biochem.8b00953