Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zachary I. Imam"'
Publikováno v:
RSC Advances. 10:42810-42815
The gliding motility of microtubule filaments has been used to study the biophysical properties of kinesin motors, as well as being used in a variety of nanotechnological applications. While microtubules are generally stabilized in vitro with paclita
Autor:
Carl C. Hayden, Zachary I. Imam, Jeanne C. Stachowiak, Morgan Mendicino, Andrea N. Trementozzi
Publikováno v:
Langmuir
Most small molecule chemotherapeutics must cross one or more cellular membrane barriers to reach their biochemical targets. Owing to the relatively low solubility of chemotherapeutics in the lipid membrane environment, high doses are often required t
Publikováno v:
RSC advances. 10(70)
The gliding motility of microtubule filaments has been used to study the biophysical properties of kinesin motors, as well as being used in a variety of nanotechnological applications. While microtubules are generally stabilized
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Dynamic instability of microtubules is characterized by stochastically alternating phases of growth and shrinkage and is hypothesized to be controlled by the conformation and nucleotide state of tubulin dimers within the microtubule lattice. Specific
Autor:
Zachary I. Imam, Laura E. Kenyon, Grant Ashby, Fatema Nagib, Morgan Mendicino, Chi Zhao, Avinash K. Gadok, Jeanne C. Stachowiak
Publikováno v:
Cellular and Molecular Bioengineering
From viruses to organelles, fusion of biological membranes is used by diverse biological systems to deliver macromolecules across membrane barriers. Membrane fusion is also a potentially efficient mechanism for the delivery of macromolecular therapeu
Autor:
George D. Bachand, Zachary I. Imam
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 35(49)
Cytoskeletal filaments and motor proteins are critical components in the transport and reorganization of membrane-based organelles in eukaryotic cells. Previous studies have recapitulated the microtubule-kinesin transport system in vitro to dynamical
Autor:
Laura E. Kenyon, Chi Zhao, Jeanne C. Stachowiak, Morgan Mendicino, Grant Ashby, Fatema Nagib, Avinash K. Gadok, Zachary I. Imam
Publikováno v:
Cellular and molecular bioengineering. 10(6)
From viruses to organelles, fusion of biological membranes is used by diverse biological systems to deliver macromolecules across membrane barriers. Membrane fusion is also a potentially efficient mechanism for the delivery of macromolecular therapeu
Autor:
Virginia VanDelinder, Haneen Martinez, Erik David Spoerke, Zachary I. Imam, George D. Bachand
Publikováno v:
Nanoscale. 11(24)
Structural defects can determine and influence various properties of materials, and many technologies rely on the manipulation of defects (e.g., semiconductor industries). In biological systems, management of defects/errors (e.g. DNA repair) is criti
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Kinesin motors and their associated filaments, microtubules, are essential to many biological processes. The motor and filament system can be reconstituted in vitro with the surface-adhered motors transporting the filaments along the surface. In this
Autor:
Laura E. Kenyon, Jeanne C. Stachowiak, Zachary I. Imam, Isai Espinoza, Fatema Nagib, Adelita Carrillo
Publikováno v:
Langmuir. 32:3774-3784
Lipid rafts are thought to be key organizers of membrane-protein complexes in cells. Many proteins that interact with rafts have bulky polymeric components such as intrinsically disordered protein domains and polysaccharide chains. Therefore, underst