Výsledky vyhledávání - "Zachary Grunwald"

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

Autor: Daniel Bernstein, Jing Liu, Pilar Ruiz-Lozano, Victoria N. Parikh, Zachary Grunwald, Alex C.Y. Chang, Ching Shang, Thomas Quertermous, Mingming Zhao, David Charo, Christopher E. Woods, Yong Huang, Philip S. Tsao, Euan A. Ashley, Kinya Seo

Publikováno v: H356
H348

The G protein-coupled receptor APJ is a promising therapeutic target for heart failure. Constitutive deletion of APJ in the mouse is protective against the hypertrophy-heart failure transition via elimination of ligand-independent, β-arrestin-depend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809016950797b069c8b3ca873945e833
https://doi.org/10.1152/ajpheart.00693.2017

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Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs

Autor: Nancy Hun, Christopher L. Moore, Kristin H. Dwyer, Jane Hall, Michael Vrablik, Alexandra Schick, Andrew S. Liteplo, Rachel Liu, Daniel L. Shaw, Rachel M. Haney, Michael B. Stone, James I. Daley, M. Kennedy Hall, Zachary Grunwald

Publikováno v: Academic emergency medicine : official journal of the Society for Academic Emergency MedicineReferences. 26(11)

BACKGROUND Focused cardiac ultrasound (FOCUS) is insensitive for pulmonary embolism (PE). Theoretically, when a clot is large enough to cause vital sign abnormalities, it is more likely to show signs of right ventricular dysfunction on FOCUS, althoug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf3152611bfc955d3f675ab1aed8b76
https://pubmed.ncbi.nlm.nih.gov/31562679

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In Vivo Post–Cardiac Arrest Myocardial Dysfunction Is Supported by Ca 2+ /Calmodulin-Dependent Protein Kinase II–Mediated Calcium Long-Term Potentiation and Mitigated by Alda-1, an Agonist of Aldehyde Dehydrogenase Type 2

Publikováno v: Circulation. 134:961-977

Background: Survival after sudden cardiac arrest is limited by postarrest myocardial dysfunction, but understanding of this phenomenon is constrained by a lack of data from a physiological model of disease. In this study, we established an in vivo mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10f1f3cc4936b61c75426c08f6a12705
https://doi.org/10.1161/circulationaha.116.021618

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Decompressive Craniectomy in Neurocritical Care

Autor: Erik G. Hayman, Zachary Grunwald, David B. Kurland, Kevin N. Sheth, J. Marc Simard, Sebastian Urday

Publikováno v: Seminars in neurology. 36(6)

Neurosurgeons increasingly use decompressive craniectomy (DC) in neurocritical care. In this review, the authors summarize the topic of DC for the neurointensivist. Following a brief overview of the procedure, the major indications for the procedure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9765fbe769a22a7ffffc6cc4f0e0ce03
https://pubmed.ncbi.nlm.nih.gov/27907955

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Abstract WMP88: Perihematomal Edema Expansion Rate Predicts Functional Outcome in Deep Intracerebral Hemorrhage

Autor: Zachary Grunwald, Sebastian Urday, Lauren A Beslow, Anastasia Vashkevich, Alison Ayres, Steven M Greenberg, Joshua N Goldstein, Thomas W Battey, J M Simard, Jonathan Rosand, W T Kimberly, Kevin N Sheth

Publikováno v: Stroke. 47

Introduction: Perihematomal edema (PHE) expansion rate may be an independent predictor of poor functional outcome following spontaneous intracerebral hemorrhage (ICH). We examined whether this association varies by ICH location. Hypothesis: The effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1cca2ccc135f0769c83f311fa479eb6
https://doi.org/10.1161/str.47.suppl_1.wmp88

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In Vivo Post-Cardiac Arrest Myocardial Dysfunction Is Supported by Ca2+/Calmodulin-Dependent Protein Kinase II-Mediated Calcium Long-Term Potentiation and Mitigated by Alda-1, an Agonist of Aldehyde Dehydrogenase Type 2

Publikováno v: Circulation. 134(13)

Survival after sudden cardiac arrest is limited by postarrest myocardial dysfunction, but understanding of this phenomenon is constrained by a lack of data from a physiological model of disease. In this study, we established an in vivo model of cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b745f5360ab3ed26a41fce8520682a9
https://pubmed.ncbi.nlm.nih.gov/27582424

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