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pro vyhledávání: '"Zachary Gardell"'
Autor:
Amanda J Audesse, Shleshma Dhakal, Lexi-Amber Hassell, Zachary Gardell, Yuliya Nemtsova, Ashley E Webb
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008097 (2019)
Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defect
Externí odkaz:
https://doaj.org/article/fc3e45a40a744edcad46e21a8f4a8f5e
Autor:
Vikas Daggubati, Abrar Choudhury, Akshara Vykunta, Olivier Saulnier, Zachary Gardell, Jeremy Reiter, Michael Taylor, David Raleigh
Publikováno v:
Neuro-Oncology. 24:vii45-vii45
Misactivation of the Hedgehog pathway can cause cancers such as medulloblastomas, the most common malignant brain tumors in children. Hedgehog signals are transmitted through primary cilia, where Hedgehog ligands bind to Patched1 and activate Smoothe
Autor:
Yuliya Nemtsova, Lexi-Amber Hassell, Ashley E. Webb, Shleshma Dhakal, Amanda J Audesse, Zachary Gardell
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008097 (2019)
PLoS Genetics
PLoS Genetics
Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defect