Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zachary Franklin Zimmerman"'
Autor:
Lynley V. Marshall, Brenda J. Weigel, G. Lesa, Joe McDonough, Malcolm A. Smith, Gudrun Schleiermacher, Nick Bird, Franca Ligas, Elly Barry, Yael P. Mosse, D Valteau, Eric J. Lowe, Nicholas Richardson, François Doz, Meredith S. Irwin, Zachary Franklin Zimmerman, Toby Trahair, Koen Norga, Sonia Singh, Martha Donoghue, Steven G. DuBois, Susan L. Weiner, Michela Casanova, Giovanni Selvaggi, Andrew D.J. Pearson, Dominik Karres, Yousif Matloub, Keith D. Wilner, Teresa de Rojas, Nicole Scobie, Rajkumar Venkatramani, Gilles Vassal, H.N. Caron, Amar Gajjar, Amy Barone, Patricia Blanc, Margret Merino, Diana Bradford, Gregory H. Reaman, Willi Woessmann, Elizabeth Fox, Vickie Buenger, Julie Park, Karsten Nysom
Publikováno v:
European Journal of Cancer. 157:198-213
The first (2017) and sixth (2021) multistakeholder Paediatric Strategy Forums focused on anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies. ALK is an important oncogene and target in several paediatric tumours (anaplastic large c
Autor:
Shiraj Sen, Lyudmilla Bazhenova, Le, X.[Le, X.], Je-Ho Lee, Mariano Ponz-Sarvise, Xuan, D.[Xuan, D.], Zachary Franklin Zimmerman, Rebecca S. Heist, David S. Hong, Junming, Z.[Junming, Z.], Byoung Chul Cho
Publikováno v:
European Journal of Cancer. 138:S1
Autor:
Xin Zhang, Vivek Subbiah, Evan Rogers, Dayong Zhai, Laura Rodon, Brion W. Murray, Wei Deng, Dong Lee, Armin Graber, Ung Jane, Alexander Drilon, Zachary Franklin Zimmerman
Publikováno v:
Journal of Clinical Oncology. 38:3616-3616
3616 Background: RET fusions/mutations drive oncogenesis in lung and thyroid cancers, and several other malignancies. Selective RET inhibitors (selpercatinib/pralsetinib) are active in patients with these cancers; unfortunately, resistance often occu
Autor:
Shiraj Sen, Zachary Franklin Zimmerman, Haeseong Park, Rebecca S. Heist, Shirish M. Gadgeel, David S. Hong, Lyudmila Bazhenova
Publikováno v:
Journal of Clinical Oncology. 38:TPS3663-TPS3663
TPS3663 Background: Alterations in the MET gene, including amplifications, chromosomal translocations, and activating mutations (kinase domain [KD] or exon 14 [Δex14]), occur across various tumors and may function as oncogenic drivers. SRC family ki
Autor:
T. Hu, H. Zhuang, Zachary Franklin Zimmerman, Dong Lee, Vivek Subbiah, Armin Graber, Jeffrey P. Whitten, J. Jean Cui, Ung Jane, Y. Lu, Dayong Zhai, Wei Deng, J. Liu, R. Xin, Zhongdong Huang, Han Zhang, Evan Rogers, Xin Zhang, A. Drilon
Publikováno v:
Annals of Oncology. 30:v190-v191
Background Oncogenic activation of the receptor tyrosine kinase (RTK) RET via point mutation or genomic rearrangement has been identified in multiple cancers, including medullary and papillary thyroid cancers, and non-small cell lung cancer (NSCLC).
Autor:
Amandeep Godara, John A. Thompson, Sylvia Lee, Zachary Franklin Zimmerman, Amila Patel, Anna Brown, Kim Margolin, Jason K. Rockhill, Jon Smith, Barry E. Storer, Scott S. Tykodi, Shailender Bhatia
Publikováno v:
Journal of Clinical Oncology. 31:e20048-e20048
e20048 Background: Ipi (anti-CTLA4 antibody) is associated with improved survival and durable responses in a subset of melanoma pts. However, the optimal dose and schedule remain unclear and an unmet need to identify predictors of clinical benefit ex