Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Zachary F Mainen"'
Publikováno v:
eLife, Vol 13 (2024)
The ability to persist toward a desired objective is a fundamental aspect of behavioral control whose impairment is implicated in several behavioral disorders. One of the prominent features of behavioral persistence is that its maturation occurs rela
Externí odkaz:
https://doaj.org/article/ace5cf85581e46029177f2f5282a515a
Autor:
International Brain Laboratory, Valeria Aguillon, Dora E Angelaki, Hannah Bayer, Niccolo Bonacchi, Matteo Carandini, Fanny Cazettes, Gaelle Chapuis, Anne K Churchland, Yang Dan, Eric Dewitt, Mayo Faulkner, Hamish Forrest, Laura Haetzel, Michael Häusser, Sonja B Hofer, Fei Hu, Anup Khanal, Christopher Krasniak, Ines Laranjeira, Zachary F Mainen, Guido Meijer, Nathaniel Miska, Thomas D Mrsic-Flogel, Masayoshi Murakami, Jean-Paul Noel, Alejandro Pan-Vazquez, Cyrille Rossant, Joshua Sanders, Karolina Socha, Rebecca Terry, Anne E Urai, Hernando Vergara, Miles Wells, Christian Wilson, Ilana B Witten, Lauren Wool, Anthony M Zador
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/80fd4519b0bd4d0693ae16b89abbd5f7
Autor:
André G. Mendonça, Jan Drugowitsch, M. Inês Vicente, Eric E. J. DeWitt, Alexandre Pouget, Zachary F. Mainen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Here, the authors show that rats’ performance on olfactory decision tasks is best explained by a Bayesian model that combines reinforcement-based learning with accumulation of uncertain sensory evidence. The results suggest that learning is a criti
Externí odkaz:
https://doaj.org/article/cdd0caa3d0de4532b42841435d503f3e
Autor:
The International Brain Laboratory, Valeria Aguillon-Rodriguez, Dora Angelaki, Hannah Bayer, Niccolo Bonacchi, Matteo Carandini, Fanny Cazettes, Gaelle Chapuis, Anne K Churchland, Yang Dan, Eric Dewitt, Mayo Faulkner, Hamish Forrest, Laura Haetzel, Michael Häusser, Sonja B Hofer, Fei Hu, Anup Khanal, Christopher Krasniak, Ines Laranjeira, Zachary F Mainen, Guido Meijer, Nathaniel J Miska, Thomas D Mrsic-Flogel, Masayoshi Murakami, Jean-Paul Noel, Alejandro Pan-Vazquez, Cyrille Rossant, Joshua Sanders, Karolina Socha, Rebecca Terry, Anne E Urai, Hernando Vergara, Miles Wells, Christian J Wilson, Ilana B Witten, Lauren E Wool, Anthony M Zador
Publikováno v:
eLife, Vol 10 (2021)
Progress in science requires standardized assays whose results can be readily shared, compared, and reproduced across laboratories. Reproducibility, however, has been a concern in neuroscience, particularly for measurements of mouse behavior. Here, w
Externí odkaz:
https://doaj.org/article/0607a5000b744a54a235fb64586a4ba3
Autor:
Fanny Cazettes, Luca Mazzucato, Masayoshi Murakami, Joao P. Morais, Elisabete Augusto, Alfonso Renart, Zachary F. Mainen
Publikováno v:
Nat Neurosci
In any given situation, the environment can be parsed in different ways to yield decision variables (DVs) defining strategies useful for different tasks. It is generally presumed that the brain only computes a single DV defining the current behaviora
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Serotonin (5-HT) plays many important roles in reward, punishment, patience and beyond, and optogenetic stimulation of 5-HT neurons has not crisply parsed them. The authors report a novel analysis of a reward-based decision-making experiment, and sho
Externí odkaz:
https://doaj.org/article/d7bc3de7103a474cb12f9bf2b53a8a92
Autor:
Eran Lottem, Dhruba Banerjee, Pietro Vertechi, Dario Sarra, Matthijs oude Lohuis, Zachary F. Mainen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Serotonin (5-HT) has been suggested to promote waiting through behavioral inhibition. Here, the authors use an active foraging task and optogenetic activation of 5-HT neurons to show that rather than passivity, these neurons enhance persistence in th
Externí odkaz:
https://doaj.org/article/8a5975b23d504b71bf9c4db21d860cf5
Autor:
Fuat Balci, Suliann Ben Hamed, Thomas Boraud, Sébastien Bouret, Thomas Brochier, Cédric Brun, Jeremiah Y. Cohen, Etienne Coutureau, Marc Deffains, Valérie Doyère, Georgia G. Gregoriou, J. Alexander Heimel, Bjørg Elisabeth Kilavik, Daeyeol Lee, Eric C. Leuthardt, Zachary F. Mainen, Mackenzie Mathis, Ilya E. Monosov, Jérémie Naudé, Amy L. Orsborn, Camillo Padoa-Schioppa, Emmanuel Procyk, Bernardo Sabatini, Jérôme Sallet, Carmen Sandi, Jeffrey D. Schall, Alireza Soltani, Karel Svoboda, Charles R.E. Wilson, Jan Zimmermann
Publikováno v:
Neuron
Neuron, 2023, 111 (5), pp.604-605. ⟨10.1016/j.neuron.2023.02.009⟩
Neuron, 111(5), 604-605. Cell Press
Neuron, 2023, 111 (5), pp.604-605. ⟨10.1016/j.neuron.2023.02.009⟩
Neuron, 111(5), 604-605. Cell Press
International audience; The article ‘In vitro neurons learn and exhibit sentience when embodied in a simulated game-world’ by Kagan et al. triggered a wave of positive mainstream and scientific media coverage as well as a widespread negative reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e09fe363e92fb93c38eeef8e052117
https://hal.science/hal-04012408
https://hal.science/hal-04012408
Publikováno v:
eLife, Vol 6 (2017)
Serotonin is implicated in mood and affective disorders. However, growing evidence suggests that a core endogenous role is to promote flexible adaptation to changes in the causal structure of the environment, through behavioral inhibition and enhance
Externí odkaz:
https://doaj.org/article/f4a9288154454057bbc022165afa1be9
Autor:
Patrícia A Correia, Eran Lottem, Dhruba Banerjee, Ana S Machado, Megan R Carey, Zachary F Mainen
Publikováno v:
eLife, Vol 6 (2017)
Serotonin (5-HT) is associated with mood and motivation but the function of endogenous 5-HT remains controversial. Here, we studied the impact of phasic optogenetic activation of 5-HT neurons in mice over time scales from seconds to weeks. We found t
Externí odkaz:
https://doaj.org/article/5bf608e47fe34554b06807242fb574ad