Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Zachary Demko"'
Autor:
George Osuchukwu, MD, Alexa Trevino, CMA, Sarah McCormick, PhD, Navchetan Kaur, PhD, Brittany Prigmore, MSc, Nour Al Haj Baddar, PhD, Michelle S. Bloom, PhD, Zachary Demko, PhD, Philippe Gauthier, MD, MBA
Publikováno v:
Transplantation Direct, Vol 10, Iss 4, p e1610 (2024)
Background. Immunosuppression therapy (IST) is required for allograft survival but can cause significant adverse effects. Donor-derived cell-free DNA (dd-cfDNA) is a validated noninvasive biomarker for active rejection in kidney transplant (KTx). Evi
Externí odkaz:
https://doaj.org/article/90c4906985ab44aeaa206d9759190914
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 16, p 4760 (2022)
Non-invasive prenatal testing (NIPT) for trisomies 21, 18, 13 and monosomy X is widely utilized with massively parallel shotgun sequencing (MPSS), digital analysis of selected regions (DANSR), and single nucleotide polymorphism (SNP) analyses being t
Externí odkaz:
https://doaj.org/article/f781896840c542d594b2b7cca0378b73
Autor:
Eser Kirkizlar, Bernhard Zimmermann, Tudor Constantin, Ryan Swenerton, Bin Hoang, Nicholas Wayham, Joshua E. Babiarz, Zachary Demko, Robert J. Pelham, Stephanie Kareht, Alexander L. Simon, Kristine N. Jinnett, Matthew Rabinowitz, Styrmir Sigurjonsson, Matthew Hill
Publikováno v:
Translational Oncology, Vol 8, Iss 5, Pp 407-416 (2015)
We demonstrate proof-of-concept for the use of massively multiplexed PCR and next-generation sequencing (mmPCR-NGS) to identify both clonal and subclonal copy-number variants (CNVs) in circulating tumor DNA. This is the first report of a targeted met
Externí odkaz:
https://doaj.org/article/7d066fbaf8d04bb1b6461ca5636564b1
Autor:
Wendy DiNonno, Zachary Demko, Kimberly Martin, Paul Billings, Melissa Egbert, Susan Zneimer, Dianne Keen-Kim, Peter Benn
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 9, p 1311 (2019)
Non-invasive prenatal screening (NIPS) based on the analysis of cell-free DNA in maternal plasma has been shown to have high sensitivity and specificity. We gathered follow-up information for pregnancies in women with test-positive NIPS results from
Externí odkaz:
https://doaj.org/article/52e8a101183a437b8ae61d3e86d3dc80
Autor:
Carole Samango-Sprouse, Eser Kırkızlar, Megan P Hall, Patrick Lawson, Zachary Demko, Susan M Zneimer, Kirsten J Curnow, Susan Gross, Andrea Gropman
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161045 (2016)
X&Y chromosomal aneuploidies are among the most common human whole-chromosomal copy number changes, but the population-based incidence and prevalence in the child-bearing population is unclear.This retrospective analysis of prospectively collected da
Externí odkaz:
https://doaj.org/article/d12ae733980340c5ad68455cfc4b9385
Autor:
Megan P Hall, Matthew Hill, Bernhard Zimmermann, Styrmir Sigurjonsson, Margaret Westemeyer, Jennifer Saucier, Zachary Demko, Matthew Rabinowitz
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96677 (2014)
PURPOSE:To determine how a single nucleotide polymorphism (SNP)- and informatics-based non-invasive prenatal aneuploidy test performs in detecting trisomy 13. METHODS:Seventeen trisomy 13 and 51 age-matched euploid samples, randomly selected from a l
Externí odkaz:
https://doaj.org/article/5845311b4bc8454aacf11836f7a23bb9
Autor:
Mary E. Norton, Cora MacPherson, Zachary Demko, Melissa Egbert, Fergal Malone, Ronald J. Wapner, Ashley S. Roman, Asma Khalil, Revital Faro, Rajeevi Madankumar, Noel Strong, Sina Haeri, Robert Silver, Nidhi Vohra, Jon Hyett, Kimberly Martin, Matthew Rabinowitz, Bo Jacobsson, Pe’er Dar
Publikováno v:
American Journal of Obstetrics and Gynecology.
Autor:
Mark Fajardo, Meenakshi Malhotra, Y. Qazi, Philippe Gauthier, Hossein Tabriziani, Anup M. Patel, Paul Billings, Ebad Ahmed, Gordon Fehringer, Zachary Demko, Sarah McCormick
Publikováno v:
Transplantation Proceedings. 53:2866-2872
Background Donor-derived cell-free DNA (dd-cfDNA) in plasma is an established noninvasive biomarker for allograft injury and rejection. A single-nucleotide polymorphism (SNP)–based massively multiplexed polymerase chain reaction methodology can be
Autor:
Philip F. Halloran, Jeff Reeve, Katelynn S. Madill-Thomsen, Zachary Demko, Adam Prewett, Philippe Gauthier, Paul Billings, Christopher Lawrence, Dave Lowe, Luis G. Hidalgo
Publikováno v:
Transplantation.
Trifecta (ClinicalTrials.gov #NCT04239703) is a prospective trial defining relationships between donor-derived cell-free DNA (dd-cfDNA), donor-specific antibody (DSA), and molecular findings in kidney transplant biopsies. Previous analyses of double
Autor:
Kimberly Martin, Pe’er Dar, Cora MacPherson, Melissa Egbert, Zachary Demko, Sheetal Parmar, Katelyn Hashimoto, Sina Haeri, Fergal Malone, Ronald J. Wapner, Ashley S. Roman, Asma Khalil, Revital Faro, Rajeevi Madankumar, Noel Strong, Robert M. Silver, Nidhi Vohra, Jon Hyett, Matt Rabinowitz, Charlly Kao, Hakon Hakonarson, Bo Jacobsson, Mary E. Norton
Publikováno v:
Genetics in Medicine. :100879