Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Zachary D. Tucker"'
1
Akademický článek
Interionic bonding in aqueous phosphonium ionic liquid solutions exhibiting LCST behavior with high phase separation temperatures
Autor: Eva M. Gulotty, Sidharth Sanadhya, Katelyn A. Wendt, Zachary D. Tucker, Saeed S. Moghaddam, Brandon L. Ashfeld
Publikováno v: Journal of Ionic Liquids, Vol 4, Iss 1, Pp 100077- (2024)
Phosphonium-derived ionic liquids have emerged as a powerful class of thermoresponsive materials with sought after Lower Critical Solution Temperature (LCST) phase separation with applications across a broad range of fields. Herein, we report the spe
Externí odkaz: https://doaj.org/article/7af37dcf7bd644b99c8147f5f93ded78
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2
Akademický článek
Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection
Autor: Daniel E. Hammers, Deborah L. Donahue, Zachary D. Tucker, Brandon L. Ashfeld, Victoria A. Ploplis, Francis J. Castellino, Shaun W. Lee
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive human pathogen that employs several secreted and surface-bound virulence factors to manipulate its environment, allowing it to cause a variety of disease outcomes. One such virule
Externí odkaz: https://doaj.org/article/397b7e5730124dff91f61b76073941ea
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3
Akademický článek
Ionic liquid enables highly efficient low temperature desalination by directional solvent extraction
Autor: Jiaji Guo, Zachary D. Tucker, Yu Wang, Brandon L. Ashfeld, Tengfei Luo
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Directional Solvent Extraction is an emerging non-membrane desalination technology for sea water desalination but is limited by throughput and energy efficiency. Here, the authors demonstrate that the production rate and energy efficiency can be incr
Externí odkaz: https://doaj.org/article/908fcf8b42a84fd288981c4e5378393f
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5
(4+1)-Cycloadditions Exploiting the Biphilicity of Oxyphosphonium Enolates and RhII/PdII-Stabilized Metallocarbenes for the Construction of Five-Membered Frameworks
Autor: Brandon L. Ashfeld, Zachary D. Tucker
Publikováno v: Synlett. 32:1157-1168
(4+1)-Cyclizations are an underutilized disconnect for the formation of five-membered heterocyclic and carbocyclic frameworks. Herein we analyze methods employing oxyphosphonium enolates and RhII/PdII-metallocarbenes as C1 synthons in the presence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45bc9b307d534b6200c44feecc771caf
https://doi.org/10.1055/s-0040-1706009
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6
Ionic liquid enables highly efficient low temperature desalination by directional solvent extraction
Autor: Tengfei Luo, Brandon L. Ashfeld, Jiaji Guo, Zachary D. Tucker, Yu Wang
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications
Seawater desalination plays a critical role in addressing the global water shortage challenge. Directional Solvent Extraction (DSE) is an emerging non-membrane desalination technology that features the ability to utilize very low temperature waste he
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e1c99ba5ab300ea597dc4ab14dbd45
https://doaj.org/article/908fcf8b42a84fd288981c4e5378393f
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7
Diverting β-Hydride Elimination of a π-Allyl PdII Carbene Complex for the Assembly of Disubstituted Indolines via a Highly Diastereoselective (4 + 1)-Cycloaddition
Autor: Zachary D. Tucker, Brandon L. Ashfeld, Andrew L. Smith, Harrison M. Hill
Publikováno v: Organic Letters. 22:6605-6609
A Pd0-catalyzed formal (4 + 1)-cycloaddition approach to 2,3-disubstituted dihydroindoles is described. The diastereoselective formation of dihydroindoles that is highlighted by a carbene migratory...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8da9cf5ffd0de334e61a94ac84bb3870
https://doi.org/10.1021/acs.orglett.0c02374
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9
Rational Design and Identification of Harmine-Inspired, N-Heterocyclic DYRK1A Inhibitors Employing a Functional Genomic In Vivo Drosophila Model System
Autor: Francisco J. Huizar, Harrison M. Hill, Emily P. Bacher, Kaitlyn E. Eckert, Eva M. Gulotty, Kevin X. Rodriguez, Zachary D. Tucker, Monimoy Banerjee, Haining Liu, Olaf Wiest, Jeremiah Zartman, Brandon L. Ashfeld
Publikováno v: ChemMedChem. 17(4)
Deregulation of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) plays a significant role in developmental brain defects, early-onset neurodegeneration, neuronal cell loss, dementia, and several types of cancer. Herein, we repor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9114835344c6aca773d9afebe6b94634
https://pubmed.ncbi.nlm.nih.gov/34994084
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