Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zachary D. Smith"'
Autor:
Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky, Christina Riemenschneider, Zachary D. Smith, Iftach Nachman, Alexander Meissner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Barriers underlying the inefficiency of reprogramming cells to pluripotency are poorly defined. Here the authors identify a transient interval soon after pluripotency exit that permits high-efficiency reprogramming and is facilitated by OCT4 bound el
Externí odkaz:
https://doaj.org/article/ecff860b9f7e4f0fa81f283c7a870aea
Publikováno v:
Stem Cell Reports, Vol 2, Iss 3, Pp 245-252 (2014)
Pluripotent stem cells retain the ability to differentiate into the three germ layers and germline. As a result, there is a major interest in characterizing regulators that establish and maintain pluripotency. The network of transcription factors con
Externí odkaz:
https://doaj.org/article/9bed8b933f074c97aa3d2607cf1ac465
Autor:
Michael J. Braunagel, W. Ashley Griffith, Robert F. Biek, David B. Hacker, Peter D. Rowley, David H. Malone, Danika Mayback, Tiffany A. Rivera, Zachary Loffer, Zachary D. Smith
Publikováno v:
Geochemistry, Geophysics, Geosystems. 24
Autor:
Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Simon J. Elsässer, Helene Kretzmer, Zachary D. Smith, Alexander Meissner
Publikováno v:
Nature Cell Biology
DNA and Histone 3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals, the majority of the genome is kept in a DNA methylated state, whereas the Polycomb repressive complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d193c70d47a07e4ccd7fa7838357e2d0
https://hdl.handle.net/21.11116/0000-000D-1F8D-321.11116/0000-000D-1F8F-1
https://hdl.handle.net/21.11116/0000-000D-1F8D-321.11116/0000-000D-1F8F-1
Autor:
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz
Publikováno v:
Nature Genetics
Most endogenous retroviruses (ERVs) in mammals are incapable of retrotransposition; therefore, why ERV derepression is associated with lethality during early development has been a mystery. Here, we report that rapid and selective degradation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aacb99499b9548036da3facfd0de18a
https://hdl.handle.net/21.11116/0000-000D-15FB-121.11116/0000-000D-15F9-3
https://hdl.handle.net/21.11116/0000-000D-15FB-121.11116/0000-000D-15F9-3
Autor:
Zachary D. Smith, W. Ashley Griffith
Publikováno v:
Tectonophysics. 838:229471
Publikováno v:
Biophysical Journal. 121:523a-524a
SUMMARYGenomic imprinting and X chromosome inactivation (XCI) require epigenetic mechanisms to direct allele-specific expression. Despite their critical roles in embryonic development, how universal epigenetic regulators coordinate these specific tas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d818d04d8bc7dc643602c09e0e8884a
https://doi.org/10.1101/2021.04.30.442087
https://doi.org/10.1101/2021.04.30.442087
Ulcerative Colitis With Concomitant Serrated Polyposis Syndrome: A Case Report and Literature Review
Publikováno v:
Cureus
Serrated polyposis syndrome (SPS) is a pre-cancerous condition associated with increased risk of developing colorectal cancer (CRC). Its role in inflammatory bowel disease (IBD)-associated CRC remains unknown. Despite the growing understanding and re
Autor:
Ebubekir S. Daglilar, Zachary D. Smith, Naren Nallapeta, Alhareth Al Juboori, Neal Sharma, Ahmed Swi
Publikováno v:
American Journal of Gastroenterology. 116:S558-S559