Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zachary Buchan"'
Autor:
Guanghu Tong, Samantha Griffin, Avery Sader, Anna B. Crowell, Ken Beavers, Jerry Watson, Zachary Buchan, Shuming Chen, Ryan A. Shenvi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Minor changes to complex structures can exert major influences on synthesis strategy and functional properties. Here we explore two parallel series of picrotoxinin (PXN, 1) analogs and identify leads with selectivity between mammalian and in
Externí odkaz:
https://doaj.org/article/6e591d0e58514b70af6f7d48884af0c8
Autor:
Guanghu Tong, Samantha Griffin, Avery Sader, Anna Crowell, Ken Beavers, Jerry Watson, Zachary Buchan, Shuming Chen, Ryan Shenvi
Natural product total synthesis enables gain of function through deep-seated modification of structure. Synthetic difficulty can, however, obstruct meaningful optimization campaigns. To simplify access, the complexity of the target (TGT) can be lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f6c04850d60085ab6bcfc881a826074
https://doi.org/10.26434/chemrxiv-2022-0l4nt
https://doi.org/10.26434/chemrxiv-2022-0l4nt
Autor:
Chenglin Yao, Kevin G. Meyer, Zachary Buchan, Ben Nugent, Karla Bravo-Altamirano, Brian Loy, Jared Rigoli, David M. Jones, Jeremy Wilmot, Kyle A. DeKorver, John F. Daeuble, Ron Heemstra, Jessica Herrick, Yu Lu, Johnathan E. Delorbe
Publikováno v:
Bioorganicmedicinal chemistry. 50
Natural products have routinely been used both as sources of and inspiration for new crop protection active ingredients. The natural product UK-2A has potent anti-fungal activity but lacks key attributes for field translation. Post-fermentation conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9447094dbf8fe66a77a48af198b5bda
https://pubmed.ncbi.nlm.nih.gov/34757295
https://pubmed.ncbi.nlm.nih.gov/34757295
Autor:
Y. Abe, Douglas D. Anspaugh, Takao Aoki, Raphael Aponte, Sadayuki Arimori, Gregory Armel, Shinichi Banba, Fabien Barreteau, James Barry, Anika Bartholomaeus, Dave Bartlett, Guillaume Berthon, Pascal Bindschaedler, Judith Blythe, Mohamed Boussemghoune, Peter Bowerman, Karla Bravo-Altamirano, Twyla A. Briddell, Zachary Buchan, A. Buchholz, Ruth Campe, Xiaofeng Cao, Jérôme Cassayre, Fredrik Cederbaum, Kang Chang, Yaning Chang, Lai Chen, Xiulei Chen, Yuzhong Chen, Jiagao Cheng, Thomas S. Churcher, Daniel Cordova, Dongliang Cui, John F. Daeuble, Peter Dahmen, H. Daido, M. Daniels, Kyle DeKorver, Jonathan DeLorbe, Alain De Mesmaeker, Philippe Desbordes, Willem Desmedt, Joachim Dickhaut, Jingao Dong, Myriem El Qacemi, Bernd Essigmann, Zhijin Fan, Marcus Fehr, Michael Flaeschel, A.J. Flemming, Raymonde Fonné-Pfister, Kosuke Fukatsu, Y. Furukawa, Stephanie Gary, Birgit Gockel, C.R. Godfrey, E. Godineau, Edouard Godineau, Aiying Guan, Oliver Gutbrod, Hans Ulrich Haas, Takahiro Hamada, Taku Hamamoto, M. Hamer, Nick Hamon, Hiroto Harayama, Patrick L. Havens, Hong-Wu He, Ron Heemstra, Yewande T. Henry, Katrin Hermann, Rafael Herrera, Jessica Herrick, Kangetsu Hirase, Akihiro Hisamatsu, Patrik Hoegger, Caleb W. Holyoke, M. Hoppé, O. Hueter, Kenneth A. Hughes, James S. Hunter, Nikolas Huwyler, Takuya Inoue, Mai Ito, Fukumatsu Iwahashi, M. Iwasa, Atsushi Iwata, Haowu Jia, David Jones, Junji Kadotani, Ryota Kasahara, H. Katsuta, A. Kawahara, So Kiguchi, T. Kikuchi, Jochen Kleemann, D.P. Kloer, Y. Kobayashi, M. Komoda, Christopher Koradin, Toru Koyanagi, Tina Kyndt, Mathilde Lachia, George P. Lahm, Mukul Lal, Clemens Lamberth, Peter Lancashire, Laura A. Laughlin, Robert M. Leighty, BaoJu Li, Honglin Li, Pengfei Li, Wei Li, Yongqiang Li, Zhong Li, Hong-Yan Lin, Changling Liu, Brian A. Loy, Aidang Lu, Yu Lu, Torsten Luksch, Alexandre Lumbroso, Hongjuan Ma, Peter Maienfisch, Sven Mangelinckx, Pamela G. Marrone, Simonetta Masala, M. Matsumoto, Yuichi Matsuzaki, Michael Maue, Stephen F. McCann, Charles Meng, Giovanna Meregalli, Kevin G. Meyer, Anna Michrowska-Pianowska, Thomas Mietzner, T. Mita, S. Mitani, Andrea Molt, Mauricio Morell, Masayuki Morita, M. Muehlebach, Tetsuya Murata, Kenichi Nakamoto, Y. Nakamura, T. Nakao, Jia-Xu Nan, Trevor Newton, Yoshihiko Nokura, M. Nomura, R. Nourani, S. Oliver, Satoshi Ōmura, Kazuhiko Oyama, Thomas F. Pahutski, Sabitha Papineni, Rupesh Patre, Ralph Paulini, Hao Peng, F. Perruccio, Thomas Pitterna, Matthias Pohlman, C. Popp, Aimone Porri, C.S. Prasanna, Xuhong Qian, Ren-Yu Qu, Ramya Rajan, Nancy B. Rankl, Girish Rawal, Stefano Rendine, Peter Renold, Jared Rigoli, Johannes Röckl, Hiroshi Sakaguchi, Vincent L. Salgado, Eikoh Satoh, J. Schaetzer, Hartwig Schröder, Hans-Georg Schwarz, Claudio Screpanti, Thomas Seitz, R. Senn, Guomin Shan, Xusheng Shao, Hongfeng Shen, Ellie Sherrard-Smith, Qinjie Shi, Yanxia Shi, Yoshio Shigematsu, Mamiko Shino, Helge Sierotzki, Anja Simon, R. Slater, Tomas Smejkal, Helmars Smits, Sebastian Soergel, Hongjian Song, D. Stafford, Daniel Stierli, Daniel Strickman, Sarah Sulzer-Mosse, Akiyuki Suwa, Masaki Takahashi, Xiao-song Tan, Helen Tinwell, My-Hanh T. Tong, Masamitsu Tsukamoto, Yoshihisa Tsukamoto, S. Tsukuda, Bartel Vanholme, Russell Viner, F. Vock-Hatt, Juliane Vogt, T. Wakita, Harald Walter, Gaolei Wang, Nick X. Wang, Qingmin Wang, Tao Wang, Ziwen Wang, P. Wege, Monte R. Weimer, J. Wenger, L. Wildsmith, Derek W. Willis, Jeremy Wilmot, Christian Winter, Matthias Witschel, Qiao Wu, Youxin Xiao, Ming Xu, Xiaoyong Xu, Yufang Xu, Zheng Xu, Hiroji Yamada, Yao-Chao Yan, Guang-Fu Yang, Jichun Yang, Wen-Chao Yang, Chenglin Yao, T. Yoneda, Yuya Yoshimoto, David Young, Jun-Lin Yuan, W. Zambach, Jingjing Zhang, Jingwei Zhang, Ruifeng Zhang, Wenming Zhang, Bin Zhao, Zhenjiang Zhao, Cong Zhou, Yuan Zhou, Weiping Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c77cfbc3b2cba7962ef272ee1a88f31
https://doi.org/10.1016/b978-0-12-821035-2.00051-6
https://doi.org/10.1016/b978-0-12-821035-2.00051-6
Autor:
David H. Young, Karla Bravo-Altamirano, Nick X. Wang, Zachary Buchan, Brian Loy, Jared Rigoli, Kyle A. DeKorver, Yu Lu, John F. Daeuble, Chenglin Yao, David M. Jones, Kevin G. Meyer, Jeremy Wilmot, Ron Heemstra, Jessica Herrick, Jonathan DeLorbe
The natural product UK-2A was transformed postfermentation to fenpicoxamid (InatreqTM active), a new crop protection active ingredient for disease control in wheat and bananas. A second-generation molecule inspired by UK-2A necessitates a nonmacrocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec140808d4a75d1c36ec7c79a4b59f7
https://doi.org/10.1016/b978-0-12-821035-2.00030-9
https://doi.org/10.1016/b978-0-12-821035-2.00030-9
Publikováno v:
Chemical Science
A new method for the intramolecular glycosylation of alcohols is described.
A new method for the intramolecular glycosylation of alcohols is described. Utilizing carbohydrate-derived silanes, the catalytic dehydrogenative silylation of alcohols
A new method for the intramolecular glycosylation of alcohols is described. Utilizing carbohydrate-derived silanes, the catalytic dehydrogenative silylation of alcohols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce14c71faca4fd3212369461ba194bc1
https://doi.org/10.1039/c5sc00810g
https://doi.org/10.1039/c5sc00810g
Autor:
Scott J. Bader, Christopher E. Taylor, John Montgomery, Zachary Buchan, Katherine M. Partridge
Publikováno v:
Angewandte Chemie International Edition. 52:13647-13650
Multipurpose sugar silanes Carbohydrate-derived silane reagents are utilized as the reductant for nickel-catalyzed aldehyde-alkyne reductive couplings, followed immediately by intramolecular glycosylation of the newly formed protected hydroxyl The ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab24c833c8317cc1eadef4d845cedc8e
https://doi.org/10.1002/anie.201307680
https://doi.org/10.1002/anie.201307680
Publikováno v:
Angewandte Chemie International Edition. 48:4840-4844
Gettin' a little sugar-no alcohol required: A procedure for the direct glycosylation of ketones without a hydroxy intermediate enables the site-selective glycosylation of hydroxyketones at the ketone or the alcohol functionality without the use of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ba7bb43ab281f141f1a9e6449d467f
https://doi.org/10.1002/anie.200901666
https://doi.org/10.1002/anie.200901666
Autor:
David J. Gonthier, Kenneth L. Brown, T. J. Sullivan, Benjamin Wurtzel, Thomas L. Bultman, Rasheed Lawal, Kenny VandenOever, Zachary Buchan
Publikováno v:
Oikos. 117:629-633
Fungal endophyte-grass associations are diverse and complex. Some endophytes (e.g. Neotyphodium spp.) reproduce asexually by growing vegetatively into host seeds and many of these vertically-transmitted endophytes form mutualisms with their hosts by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c858bed941ca36618ed3d5077f00d797
https://doi.org/10.1111/j.0030-1299.2008.16483.x
https://doi.org/10.1111/j.0030-1299.2008.16483.x
Publikováno v:
ChemInform. 40
Gettin' a little sugar-no alcohol required: A procedure for the direct glycosylation of ketones without a hydroxy intermediate enables the site-selective glycosylation of hydroxyketones at the ketone or the alcohol functionality without the use of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeefebcb0e6d00e70eda13455aed9bf5
https://doi.org/10.1002/chin.200942188
https://doi.org/10.1002/chin.200942188