Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zachary B Gillespie"'
Autor:
Matthew R Marunde, Harrison A Fuchs, Jonathan M Burg, Irina K Popova, Anup Vaidya, Nathan W Hall, Ellen N Weinzapfel, Matthew J Meiners, Rachel Watson, Zachary B Gillespie, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Sarah A Howard, Katherine Novitzky, Eileen T McAnarney, Krzysztof Krajewski, Martis W Cowles, Marcus A Cheek, Zu-Wen Sun, Bryan J Venters, Michael-C Keogh, Catherine A Musselman
Publikováno v:
eLife, Vol 13 (2024)
Histone post-translational modifications (PTMs) play a critical role in chromatin regulation. It has been proposed that these PTMs form localized ‘codes’ that are read by specialized regions (reader domains) in chromatin-associated proteins (CAPs
Externí odkaz:
https://doaj.org/article/bb8066ecda624cd69e4af12da10f5a2d
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas L Young, Michael-Christopher Keogh, Brian D Strahl
Publikováno v:
eLife, Vol 12 (2023)
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://doaj.org/article/4578fc571e78426c9ad347f2e09aa9c9
Autor:
Douglas Barrows, Matthew R. Marunde, C. David Allis, Xiao Chen, Cynthia Horth, Phillip Rosenbaum, Michael-Christopher Keogh, Daniel N. Weinberg, Irina K. Popova, Chao Lu, Jacek Majewski, Zachary B. Gillespie
Publikováno v:
Nat Genet
Precise deposition of CpG methylation is critical for mammalian development and tissue homeostasis and is often dysregulated in human diseases. The localization of de novo DNA methyltransferase DNMT3A is facilitated by its PWWP domain recognizing his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a78d76b60034f02c0ddcd6a8fa163a
https://doi.org/10.1038/s41588-021-00856-5
https://doi.org/10.1038/s41588-021-00856-5
Autor:
Zachary B. Gillespie, Neil L. Kelleher, Jonathan D. Licht, Marcus A. Cheek, Amin Sobh, Sarah A. Howard, Michael-Christopher Keogh, Luis F. Schachner, Kevin Jooß, Matthew J. Meiners, Rachel Watson
Publikováno v:
Anal Chem
We report a novel platform [native capillary zone electrophoresis–top-down mass spectrometry (nCZE–TDMS)] for the separation and characterization of whole nucleosomes, their histone subunits, and post-translational modifications (PTMs). As the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac31269a410e4f0c34ce0d226a6478e
https://doi.org/10.1021/acs.analchem.0c04975
https://doi.org/10.1021/acs.analchem.0c04975
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas Young, Michael-C Keogh, Brian D Strahl
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56293051dfd39cb6a2645e19d0fa20ad
https://doi.org/10.1101/2022.02.28.482307
https://doi.org/10.1101/2022.02.28.482307
Autor:
Marcus A. Cheek, Michael-Christopher Keogh, Kevin Jooss, Sarah A. Howard, Rachel Watson, Matthew J. Meiners, Jonathan D. Licht, Zachary B. Gillespie, Luis F. Schachner, Neil L. Kelleher
We report a novel platform (native capillary zone electrophoresis – top-down mass spectrometry; nCZE-TDMS) for the separation and characterization of whole nucleosomes, their histone subunits, and PTMs. As the repeating unit of chromatin, mononucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844f8f087ef381857f938cc8e0e24cfc
https://doi.org/10.1101/2020.11.25.398925
https://doi.org/10.1101/2020.11.25.398925