Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zachary A Pfeiffer"'
Autor:
Jan M Bruder, Zachary A Pfeiffer, Jonathan M Ciriello, Diana M Horrigan, Nadine L Wicks, Benjamin Flaherty, Elena Oancea
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43465 (2012)
Melanocytes present in skin and other organs synthesize and store melanin pigment within membrane-delimited organelles called melanosomes. Exposure of human skin to ultraviolet radiation (UV) stimulates melanin production in melanosomes, followed by
Externí odkaz:
https://doaj.org/article/587c24838ab647e3a8e01b3d54b1f4df
Autor:
Susan Madison-Antenucci, Kevin Y. Cheng, Kelly E. Coller, Susan J. Wong, Mark Pope, Thomas P. Leary, George J. Dawson, Christopher C. Marohnic, Alfredo R. Narvaez, Jeffrey R. Fishpaugh, M. Marcinkus, Phillip W. Schultz, Zachary A. Pfeiffer, Alak K. Kar, Janet M. Bergsma, Kathy Otis, Orlando H. Gumbs, James R. Fino, Randee R. Elsing
Publikováno v:
Journal of Clinical Microbiology
The tick-borne protozoan Babesia microti is responsible for more than 200 cases of transfusion-transmitted babesiosis (TTB) infection in the United States that have occurred over the last 30 years. Measures to mitigate the risk of TTB include nucleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e39ab24be8994c72fbd97de165cdecf
https://pubmed.ncbi.nlm.nih.gov/29743308
https://pubmed.ncbi.nlm.nih.gov/29743308
Autor:
Usha Prabhu, Alma N. Guerra, Paul J. Bertics, Zachary A. Pfeiffer, Monica L. Gavala, Mini Aga, David J. Hall, Lindsay M. Hill
Publikováno v:
Free Radical Biology and Medicine. 42:1506-1516
Macrophage activation is critical in the innate immune response and can be regulated by the nucleotide receptor P2X 7 . In this regard, P2X 7 signaling is not well understood but has been implicated in controlling reactive oxygen species (ROS) genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2325100d570611b6a2e576b27e46f984
https://doi.org/10.1016/j.freeradbiomed.2007.02.010
https://doi.org/10.1016/j.freeradbiomed.2007.02.010
Publikováno v:
Journal of Leukocyte Biology. 75:1173-1182
Extracellular nucleotides regulate macrophage function via P2X nucleotide receptors that form ligand-gated ion channels. In particular, P2X7 activation is characterized by pore formation, membrane blebbing, and cytokine release. P2X7 is also linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd6848c31d4be5870d6c7c91947c712
https://doi.org/10.1189/jlb.1203648
https://doi.org/10.1189/jlb.1203648
Autor:
Paul J. Bertics, Jyoti J. Watters, Gregory J. Wiepz, Zachary A. Pfeiffer, Mini Aga, Julie A. Sommer
Publikováno v:
American Journal of Physiology-Cell Physiology. 286:C923-C930
Extracellular nucleotides such as ATP are present in abundance at sites of inflammation and tissue damage, and these agents exert a potent modulatory effect on macrophage/monocyte function via the nucleotide receptor P2X7. In this regard, after expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a521b8f173bc8cb4fa8a095a390a1d0e
https://doi.org/10.1152/ajpcell.00417.2003
https://doi.org/10.1152/ajpcell.00417.2003
Autor:
Zachary A. Pfeiffer, Alma N. Guerra, Usha Prabhu, Jyoti J. Watters, Paul J. Bertics, Julie A. Sommer
Publikováno v:
Journal of Biological Chemistry. 277:9077-9087
Endotoxin (lipopolysaccharide, LPS) is a component of the outer membrane of Gram-negative bacteria and promotes the activation of macrophages and microglia. Although these cells are highly LPS-responsive, they serve unique tissue-specific functions a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697b3cf97ed2b0f19d8776bbaa0b3053
https://doi.org/10.1074/jbc.m104385200
https://doi.org/10.1074/jbc.m104385200
Autor:
Loren C. Denlinger, Usha Prabhu, Alma N. Guerra, Philip L. Fisette, Jyoti J. Watters, Zachary A. Pfeiffer, Mini Aga, Paul J. Bertics, Julie A. Sommer
Publikováno v:
Drug Development Research. 53:91-104
During infection or inflammation, high concentrations of extracellular nucleotides are released into the inflammatory microenvironment, supplying a source of ligand for purinergic receptors that are present on many immune cell types. The P2X 7 recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9470eb192bf5fe55997bae9bc0c091
https://doi.org/10.1002/ddr.1176
https://doi.org/10.1002/ddr.1176
Autor:
Lori J. Sokoll, Frans Martens, Makoto Komori, Kaori Morota, Debra J. Elliott, Zachary A. Pfeiffer, Barry L. Dowell, Annemieke C. Heijboer, Kageaki Kuribayashi, Naoki Watanabe, Daniel W. Chan, Koji Yamada, Shyam V. Vaidya, Ryo Fujinami, Stefan J. Hershberger, Marinus A. Blankenstein
Publikováno v:
Morata, K, Komori, M, Fujinami, R, Yamada, K, Kuribayashi, K, Watanabe, N, Sokoll, L J, Elliott, D, Chan, D W, Martens, F, Heijboer, A C, Blankenstein, M A, Hershberger, S J, Pfeiffer, Z A, Vaidya, S V & Dowell, B L 2012, ' Improvement and multicenter evaluation of the analytical performance of an automated chemiluminescent immunoassay for alpha fetoprotein ', International Journal of Biological Markers, vol. 27, no. 1, pp. 39-46 . https://doi.org/10.5301/JBM.2011.8738
International journal of biological markers, 27(1), 39-46. Wichtig Publishing
International Journal of Biological Markers, 27(1), 39-46. Wichtig Publishing
International journal of biological markers, 27(1), 39-46. Wichtig Publishing
International Journal of Biological Markers, 27(1), 39-46. Wichtig Publishing
Background A new ARCHITECT® alpha fetoprotein (AFP) assay was developed to improve the linearity at the upper end of the calibration curve and to enhance other performance characteristics. In addition, this reformulation eliminated the possibility o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634973b6cd7ddbc9a38035702ccbd7f5
https://research.vumc.nl/en/publications/0d368a78-adb0-48b5-9a71-119dee71af17
https://research.vumc.nl/en/publications/0d368a78-adb0-48b5-9a71-119dee71af17
Autor:
Zachary A. Pfeiffer, Julie A. Sommer, Arturo G. Guadarrama, Beatriz H. Quinchia-Rios, Usha Prabhu, Richard A. Proctor, Sara Abozeid, Loren C. Denlinger, Alma N. Guerra, Paul J. Bertics, Philip L. Fisette, Mini Aga
Publikováno v:
Journal of endotoxin research. 9(4)
Macrophages express several lipopolysaccharide (LPS) binding proteins and are potently activated by LPS to produce inflammatory mediators. Recent studies have shown that receptors for exogenous nucleotides (P2X and P2Y purinergic receptors) can modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a107ebb65f3266c03776dc3623f6a5a
https://pubmed.ncbi.nlm.nih.gov/12935357
https://pubmed.ncbi.nlm.nih.gov/12935357
Autor:
Jyoti J, Watters, Julie A, Sommer, Zachary A, Pfeiffer, Usha, Prabhu, Alma N, Guerra, Paul J, Bertics
Publikováno v:
The Journal of biological chemistry. 277(11)
Endotoxin (lipopolysaccharide, LPS) is a component of the outer membrane of Gram-negative bacteria and promotes the activation of macrophages and microglia. Although these cells are highly LPS-responsive, they serve unique tissue-specific functions a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b648d993f75255711cc6439f6e2e0cf
https://pubmed.ncbi.nlm.nih.gov/11786532
https://pubmed.ncbi.nlm.nih.gov/11786532