Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zachary, VanGundy"'
Autor:
Nathan D. Seligson, Xunjie Zhang, Mark C. Zemanek, Jasmine A. Johnson, Zachary VanGundy, Danxin Wang, Mitch A. Phelps, Julianna Roddy, Craig C. Hofmeister, Junan Li, Ming J. Poi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Introduction: Polymorphisms in genes responsible for the metabolism and transport of tacrolimus have been demonstrated to influence clinical outcomes for patients following allogeneic hematologic stem cell transplant (allo-HSCT). However, the clinica
Externí odkaz:
https://doaj.org/article/74d23d0d6a3644e1ac4dd5f599fa8963
Autor:
Melissa Thomas, Junan Li, Kevan King, Avinash K Persaud, Ernest Duah, Zachary Vangundy, Craig C. Hofmeister, Jatinder K. Lamba, Aik Choon Tan, Brooke L. Fridley, Ming J. Poi, Nathan D. Seligson
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Multiple Myeloma (MM) is an incurable plasma cell malignancy often treated by autologous stem cell transplant (ASCT). Clinical response to ASCT has been associated with DNA repair efficiency. Here we interrogated the role of the base excision DNA rep
Externí odkaz:
https://doaj.org/article/7a7b8d3edef349908f93a513689d97de
Autor:
Wolfgang Sadee, Mitch A. Phelps, Ming Jing Poi, Junan Li, Danxing Wang, Xuejie Zhang, Zachary VanGundy, Jasmine A. Johnson, Nathan D. Seligson, Craig C. Hofmeister
Publikováno v:
Anticancer Research. 40:5707-5713
Background/aim Genetic variations of the non-coding RNA gene, ANRIL, have been associated with human diseases including cancer, type-2 diabetes, and atherosclerosis. In the present study, we investigated the potential associations of select ANRIL sin
Publikováno v:
Anticancer Research. 40:67-73
Background/aim Aberrant expression of the SEI1 oncogene has been prevalently found in a variety of human cancers, including oral squamous cell carcinoma (OSCC). Recent studies have shown that cisplatin up-regulates the expression of SEI1 in breast an
Publikováno v:
Anticancer Research. 40:133-141
BACKGROUND/AIM Aberrant expression of the BMI1 oncogene has been prevalently found in a variety of human cancers, including cervical cancer. Recent studies have shown that PTC209, a specific BMI1 inhibitor, exhibits high potency in inhibiting the gro
Autor:
Junan, Li, Nathan, Seligson, Xuejie, Zhang, Jasmine, Johnson, Zachary, Vangundy, Danxing, Wang, Mitch, Phelps, Craig, Hofmeister, Wolfgang, Sadee, Ming Jing, Poi
Publikováno v:
Anticancer research. 40(10)
Genetic variations of the non-coding RNA gene, ANRIL, have been associated with human diseases including cancer, type-2 diabetes, and atherosclerosis. In the present study, we investigated the potential associations of select ANRIL single nucleotide
Autor:
Zachary VanGundy, Junan Li, Douglas W. Sborov, Misty Lamprecht, Mitch A. Phelps, Craig C. Hofmeister, Yu Kyoung Cho, Ming Poi, Flavia Pichiorri
Publikováno v:
Molecular Carcinogenesis. 56:1722-1732
Multiple myeloma (MM) is a hematologic malignancy characterized by clonal proliferation of plasma cells and overproduction of monoclonal immunoglobins. Treatment with melphalan is currently standard of care for younger and fit patients when followed
Publikováno v:
Anticancer research. 40(1)
Aberrant expression of the SEI1 oncogene has been prevalently found in a variety of human cancers, including oral squamous cell carcinoma (OSCC). Recent studies have shown that cisplatin up-regulates the expression of SEI1 in breast and bladder cance
Autor:
Ernest Duah, Zachary VanGundy, Yong Li, Ming Poi, Avinash K. Persaud, Nicholas E. Long, Thomas J. Magliery
Publikováno v:
Bioanalysis. 11(6)
Aim: To develop and validate a reliable, robust and efficient assay to detect and quantify biologic compounds in vitro and in vivo during early stage of a biotherapeutic agent discovery. Methodology & results: An enrichment-free immunoassay method wa
Autor:
Naveen Kanthamneni, Zachary VanGundy, Kevin J. Peine, Tracey L. Papenfuss, D. Probst, Priscilla W. Lee, Eric M. Bachelder, Yuhong Yang, Mary Severin, Kristy M. Ainslie, Amy E. Lovett-Racke, Haiyan Peng, Mireia Guerau-de-Arellano
Publikováno v:
Molecular Pharmaceutics
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system that can cause loss of motor function and is thought to result, in part, from chronic inflammation due to an antigen-specific T cell immune response. Curren