Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zacharie Nickens"'
Autor:
James S Testa, Vivekananda Shetty, Julie Hafner, Zacharie Nickens, Shivali Kamal, Gomathinayagam Sinnathamby, Ramila Philip
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48484 (2012)
Influenza virus infection and the resulting complications are a significant global public health problem. Improving humoral immunity to influenza is the target of current conventional influenza vaccines, however, these are generally not cross-protect
Externí odkaz:
https://doaj.org/article/8106d4993fcc43cfa92772bf3e17a563
Autor:
Vivekananda Shetty, Julie Hafner, Marti Jett, Xianchao Zhang, Gomathinayagam Sinnathamby, Ramila Philip, Zacharie Nickens, James Testa, Shivali Kamal
Publikováno v:
The Journal of Infectious Diseases. 205:647-655
Dengue fever and dengue hemorrhagic fever are significant global public health problems, and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Liv
Autor:
Zacharie Nickens, Vivekananda Shetty, Ramila Philip, Anand Mehta, Gomathinayagam Sinnathamby, Pooja Jain
Publikováno v:
OMICS: A Journal of Integrative Biology. 15:705-717
The analysis of plasma samples from HIV-1/HCV mono- and coinfected individuals by quantitative proteomics is an efficient strategy to investigate changes in protein abundances and to characterize the proteins that are the effectors of cellular functi
Autor:
Zacharie Nickens, Gordana Vlahovic, Ramila Philip, Gomathinayagam Sinnathamby, Julie Hafner, Punit Shah, Lisa Mariello, Michael A. Morse, H. Kim Lyerly, Shivali Kamal, Vivekananda Shetty
Publikováno v:
Journal of Proteomics. 74:728-743
The development of potent cancer vaccines for common malignancies such as lung cancer requires identification of suitable target antigens. We hypothesized that peptide epitopes naturally presented by MHC class I molecules on the surface of cancer cel
Autor:
Ramila Philip, Zacharie Nickens, Gomathinayagam Sinnathamby, Punit Shah, O. John Semmes, Vivekananda Shetty
Publikováno v:
Analytical Chemistry. 82:9201-9210
The accuracy in quantitative analysis of N-linked glycopeptides and glycosylation site mapping in cancer is critical to the fundamental question of whether the aberration is due to changes in the total concentration of glycoproteins or variations in
Autor:
Zacharie Nickens, Gomathinayagam Sinnathamby, James Testa, Vivekananda Shetty, Shivali Kamal, Ramila Philip, Julie Hafner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e48484 (2012)
PLoS ONE, Vol 7, Iss 11, p e48484 (2012)
Influenza virus infection and the resulting complications are a significant global public health problem. Improving humoral immunity to influenza is the target of current conventional influenza vaccines, however, these are generally not cross-protect
Autor:
Pooja Jain, Ramila Philip, Jordana Grazziela Coelho-dos-Reis, Punit Shah, Vivekananda Shetty, Andrew H. Talal, Nawal M. Boukli, Zacharie Nickens, Luis A. Cubano, Martha Ricaurte
Publikováno v:
Clinical Proteomics, Vol 9, Iss 1, p 11 (2012)
Clinical proteomics
Clinical proteomics
Background Pathogenesis of liver damage in patients with HIV and HCV co-infection is complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is increasing little is known about the pathophysiology that mediates the rapi
Autor:
Vivekananda Shetty, Zacharie Nickens, Gomathinayagam Sinnathamby, Julie Hafner, James Testa, Ramila Philip
Publikováno v:
Journal of proteomics. 75(11)
Platinum-based chemotherapy is widely used to treat various cancers including ovarian cancer. However, the mortality rate for patients with ovarian cancer is extremely high, largely due to chemo-resistant progression in patients who respond initially
Autor:
Amy Hobeika, Michael A. Morse, Herbert Kim Lyerly, Jennifer Zerfass, Zacharie Nickens, Ramila Philip, Julie Hafner, Peter Block, Gomathinayagam Sinnathamby, Angeles Alvarez Secord
Summary Selection of suitable antigens is critical for the development of cancer vaccines. Most desirable are over-expressed cell surface proteins that may serve as targets for both antibodies and T cells, thus maximizing a concerted immune response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22bb0e9805d24043de67044382bcc32
https://europepmc.org/articles/PMC3048615/
https://europepmc.org/articles/PMC3048615/
Autor:
Zacharie Nickens, Amy Hobeika, Ramila Philip, Gomathinayagam Sinnathamby, Angeles Alvarez Secord, Peter Block, Julie Hafner, Michael A. Morse, H. Kim Lyerly, Jennifer Zerfass
Publikováno v:
Journal of Clinical & Cellular Immunology. 2
Selection of suitable antigens, preferably targets for cell mediated and humoral immune response is a critical step in the development of cancer vaccines. Cell surface proteins that are over-expressed in cancer cells thus constitute a very attractive