Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Zachariah J Hoell"'
Autor:
Huarui Cui, Anand Divakaran, Zachariah J. Hoell, Mikael O. Ellingson, Cole R. Scholtz, Huda Zahid, Jorden A. Johnson, Elizabeth C. Griffith, Clifford T. Gee, Amani L. Lee, Shalil Khanal, Ke Shi, Hideki Aihara, Vijay H. Shah, Richard E. Lee, Daniel A. Harki, William C. K. Pomerantz
Publikováno v:
J Med Chem
Chemical probes for epigenetic proteins are essential tools for dissecting the molecular mechanisms for gene regulation and therapeutic development. The bromodomain and extra-terminal (BET) proteins are master transcriptional regulators. Despite prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b7a4c86e5079b9c8290b3133b80308
https://pubmed.ncbi.nlm.nih.gov/35007061
https://pubmed.ncbi.nlm.nih.gov/35007061
Autor:
Anand Divakaran, Jorden A. Johnson, Ke Shi, Huarui Cui, Hideki Aihara, Daniel A. Harki, Anil K. Pandey, Mikael O Ellingson, Huda Zahid, William C. K. Pomerantz, Zachariah J Hoell
Publikováno v:
Angew Chem Int Ed Engl
Bromodomain and extra-terminal (BET) family proteins, BRD2-4 and T, are important drug targets; however, the biological functions of each bromodomain remain ill-defined. Chemical probes that selectively inhibit a single BET bromodomain are lacking, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b79da71e3806f7d8c1a0a9ceab6903e
https://pubmed.ncbi.nlm.nih.gov/32975004
https://pubmed.ncbi.nlm.nih.gov/32975004