Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zachariah I Carter"'
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0312743 (2024)
T7 RNA Polymerase (RNAP) is a widely used enzyme with recent applications in the production of RNA vaccines. For over 50 years denaturing sequencing gels have been used as key analysis tools for probing the nucleotide addition mechanisms of T7 RNAP a
Externí odkaz:
https://doaj.org/article/c2176722597144369060404416d7f971
Autor:
Sahar Foroutannejad, Lydia L. Good, Changfan Lin, Zachariah I. Carter, Mahlet G. Tadesse, Aaron L. Lucius, Brian R. Crane, Rodrigo A. Maillard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Characterizing folding pathways of large proteins that bind complex cofactors is challenging. The authors use optical tweezers to study the 542-residue FAD-binding lightsensor protein dCRY, identifying several intermediates and cofactor binding steps
Externí odkaz:
https://doaj.org/article/30dd6d9302b84ee08c76dff6d29b567b
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105306- (2022)
Summary: Eukaryotes express three nuclear RNA polymerases (Pols I, II, and III) that are essential for cell survival. Despite extensive investigation of the three Pols, significant knowledge gaps regarding their biochemical properties remain because
Externí odkaz:
https://doaj.org/article/0134558c08134004b14bd60fea5e3d26
Publikováno v:
Biochemistry. 62(1)
Eukaryotic RNA polymerase II (Pol II) is an essential enzyme that lies at the core of eukaryotic biology. Due to its pivotal role in gene expression, Pol II has been subjected to a substantial number of investigations. We aim to further our understan
Autor:
Ruth Q. Jacobs, Kaila B. Fuller, Stephanie L. Cooper, Zachariah I. Carter, Marikki Laiho, Aaron L. Lucius, David A. Schneider
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5544
Cancer cells require robust ribosome biogenesis to maintain rapid cell growth during tumorigenesis. Because RNA polymerase I (Pol I) transcription of the ribosomal DNA (rDNA) is the first and rate-limiting step of ribosome biogenesis, it has emerged