Výsledky vyhledávání - "Zachariah, Mupila"

Akademický článek

Nasopharyngeal Dysbiosis Precedes the Development of Lower Respiratory Tract Infections in Young Infants, a Longitudinal Infant Cohort Study [version 2; peer review: 1 approved, 2 approved with reservations]

Autor: William Evan Johnson, Daniel Segrè, Christopher J Gill, William MacLeod, Donald M Thea, Tyler Faits, Rotem Lapidot, Mushal Allam, Arshad Ismail, Geoffrey Kwenda, Lawrence Mwananyanda, Zamantungwak Khumalo, Ruth Nakazwe, Zachariah Mupila

Publikováno v: Gates Open Research, Vol 6 (2024)

Background Infants suffering from lower respiratory tract infections (LRTIs) have distinct nasopharyngeal (NP) microbiome profiles that correlate with severity of disease. Whether these profiles precede the infection or are a consequence of it, is un

Externí odkaz: https://doaj.org/article/593df2dd23314435a3beaaabc6804abd

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Akademický článek

What is the prevalence of COVID-19 detection by PCR among deceased individuals in Lusaka, Zambia? A postmortem surveillance study

Publikováno v: BMJ Open, Vol 12, Iss 12 (2022)

Objectives To determine the prevalence of COVID-19 postmortem setting in Lusaka, Zambia.Design A systematic, postmortem prevalence study.Setting A busy, inner-city morgue in Lusaka.Participants We sampled a random subset of all decedents who transite

Externí odkaz: https://doaj.org/article/7ef49b34ff0f4b2d8060279cfc60fbb2

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Akademický článek

Antimicrobial Resistance Patterns and Risk Factors Associated with ESBL-Producing and MDR Escherichia coli in Hospital and Environmental Settings in Lusaka, Zambia: Implications for One Health, Antimicrobial Stewardship and Surveillance Systems

Autor: Maisa Kasanga, Geoffrey Kwenda, Jian Wu, Maika Kasanga, Mark J. Mwikisa, Raphael Chanda, Zachariah Mupila, Baron Yankonde, Mutemwa Sikazwe, Enock Mwila, Doreen M. Shempela, Benjamin B. Solochi, Christabel Phiri, Steward Mudenda, Duncan Chanda

Publikováno v: Microorganisms, Vol 11, Iss 8, p 1951 (2023)

Antimicrobial resistance (AMR) is a public health problem threatening human, animal, and environmental safety. This study assessed the AMR profiles and risk factors associated with Escherichia coli in hospital and environmental settings in Lusaka, Za

Externí odkaz: https://doaj.org/article/90b21f4d7c654269a1e06821185fffa2

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Akademický článek

Sequence Diversity of Tp1 and Tp2 Antigens and Population Genetic Analysis of Theileria parva in Unvaccinated Cattle in Zambia’s Chongwe and Chisamba Districts

Autor: Walter Muleya, David Kalenzi Atuhaire, Zachariah Mupila, Victor Mbao, Purity Mayembe, Sydney Kalenga, Paul Fandamu, Boniface Namangala, Jeremy Salt, Antony Jim Musoke

Publikováno v: Pathogens, Vol 11, Iss 2, p 114 (2022)

East Coast Fever (ECF), caused by Theileria parva, is a major constraint to improved livestock keeping in east and central Africa, including Zambia. To understand the dynamics and determine the candidates for immunization in Zambia’s Chongwe and Ch

Externí odkaz: https://doaj.org/article/14f08626a8c3484aaafb4333c916887b

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Association of Respiratory Syncytial Virus Infection and Underlying Risk Factors for Death Among Young Infants Who Died at University Teaching Hospital, Lusaka Zambia

Autor: Geoffrey Kwenda, Zachariah Mupila, Charles Chimoga, William B. MacLeod, Benard Ngoma, Baron Yankonde, Rachel Pieciak, Caitriona Murphy, Lawrence Mwananyanda, Donald M. Thea, Chilufya Chikoti, Leah S Forman, Christopher J. Gill

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Background Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections and child mortality. While RSV disease burden is highest in low- and middle-income countries, most knowledge about risk factors for fatal RSV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad7ddad4f458c214baa4f5f05b140d9
https://doi.org/10.1093/cid/ciab466

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Risk Factors for Respiratory Syncytial Virus–Associated Community Deaths in Zambian Infants

Autor: Rachel Pieciak, William B. MacLeod, Lawrence Mwananyanda, Zachariah Mupila, Baron Yankonde, Leah S Forman, Donald M. Thea, Caitriona Murphy, Bernard Ngoma, Chilufya Chikoti, Christopher J. Gill, Geoffrey Kwenda, Charles Chimoga

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Background Respiratory syncytial virus (RSV) is a major cause of infant deaths. Its epidemiology in low- and middle-income countries is poorly understood. Risk factors associated with RSV-associated infant deaths that occur in community settings are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b86b0c5a248dcd4b335910395d89648
http://europepmc.org/articles/PMC8411252

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Young Zambian infants with symptomatic RSV and pertussis infections are frequently prescribed inappropriate antibiotics

Autor: Zachariah Mupila, Christopher J. Gill, Christian E. Gunning, Pejman Rohani, Lawrence Mwananyanda, Geoffrey Kwenda

Pediatric community-acquired pneumonia (CAP) remains a pressing global health concern, particulary in low-resource settings where diagnosis and treatment rely on empiric, symptoms-based guidelines such as the WHO’s Integrated Management of Childhoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::094d35190a23261ed43a6705d131505b
https://doi.org/10.1101/2021.09.21.21263905

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