Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zach Bjornson"'
Autor:
Kenneth Kim, C. Josefina Martinez, Nima Aghaeepour, Nilanjan Mukherjee, Han Chen, Bonnie Bock, Neda Hajiakhoond Bidoki, Sean N. Tucker, David R. McIlwain, David Liebowitz, Jiang Sizun, Julien Hedou, Garry P. Nolan, Nikita S. Kolhatkar, Melton Affrime, Brice Gaudilliere, Zainab Rahil, Zach Bjornson, Angelica Trejo, Christian M. Schürch
Publikováno v:
Cell Host Microbe
Developing new influenza vaccines with improved performance and easier administration routes hinges on defining correlates of protection. Vaccine-elicited cellular correlates of protection for influenza in humans have not yet been demonstrated. A pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ccb802c6affaf4c91aa166c7326aa6
https://europepmc.org/articles/PMC8665113/
https://europepmc.org/articles/PMC8665113/
Autor:
Kayla G. Barnes, Nadine M. Khoury, Brian Sellers, Jonathan R. Kurtz, Nancy Tran, Marc H. Wadsworth, Siddharth S. Raju, Zach Bjornson, Nilanjan Mukherjee, John L. Rinn, Richard S. Bennett, Han Chen, Travis K. Hughes, David R. McIlwain, Aaron E. Lin, Alex K. Shalek, Stephen F. Schaffner, Ricky Adams, Pardis C. Sabeti, James Logue, Gordon Adams, Marta Melé, Bonnie Dighero-Kemp, Dylan Kotliar, Matthew R. Bauer, Lisa E. Hensley, Garry P. Nolan
Publikováno v:
Cell
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Summary Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to the challenge of experimentation in high-containment and outbreak settings. Here, we used single-cell transcriptomics and CyTOF-based single-cell protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6232a6425ab44c6176dbf3f417e4cc21
https://hdl.handle.net/2117/346631
https://hdl.handle.net/2117/346631
Autor:
Shannon R. Christensen, Garry P. Nolan, Nima Aghaeepour, Nilanjan Mukherjee, Sizun Jiang, Zainab Rahil, Han Chen, Jennifer Yo, Zach Bjornson-Hooper, Salil S. Bhate, Brice Gaudilliere, Matthew H. Spitzer, David R. McIlwain, Gabriela K. Fragiadakis, Pier Federico Gherardini, Rebecca Leylek, Nelson Kim, Scott E. Hensley, Kenneth Kim, Christian M. Schürch, Bonnie Bock, Juliana Idoyaga, Melton Affrime
Publikováno v:
J Clin Invest
Influenza is a significant cause of morbidity and mortality worldwide. Here we show changes in the abundance and activation states of more than 50 immune cell subsets in 35 individuals over 11 time points during human A/California/2009 (H1N1) virus c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aea9e327a93703d4165dacb1fd4a218
https://europepmc.org/articles/PMC7598057/
https://europepmc.org/articles/PMC7598057/
Autor:
Travis K. Hughes, Brian Sellers, Siddharth S. Raju, Matthew R. Bauer, David R. McIlwain, John L. Rinn, James Logue, Marta Melé, Zach Bjornson, Bonnie Dighero-Kemp, Ricky Adams, Marc H. Wadsworth, Garry P. Nolan, Han Chen, Nadine M. Khoury, Aaron E. Lin, Nilanjan Mukherjee, Pardis C. Sabeti, Richard S. Bennett, Nancy Tran, Gordon Adams, Lisa E. Hensley, Kayla G. Barnes, Jonathan R. Kurtz, Alex K. Shalek, Dylan Kotliar
SummaryEbola virus (EBOV) causes epidemics with high case fatality rates, yet remains understudied due to the challenge of experimentation in high-containment and outbreak settings. To better understand EBOV infection in vivo, we used single-cell tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed4f8495e224e520f18c1139209e9f66
https://doi.org/10.1101/2020.06.12.148957
https://doi.org/10.1101/2020.06.12.148957
Autor:
Stuart T. Nichol, Han Chen, David R. Mcllwain, Nilanjan Mukherjee, Garry P. Nolan, Rama Akondy, Anita K. McElroy, Christina F. Spiropoulou, Aneesh K. Mehta, Zach Bjornson-Hooper
Publikováno v:
JCI Insight
A complete understanding of human immune responses to Ebola virus infection is limited by the availability of specimens and the requirement for biosafety level 4 (BSL-4) containment. In an effort to bridge this gap, we evaluated cryopreserved PBMCs f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1287ba47e2002737491095f43fb851
https://europepmc.org/articles/PMC7259516/
https://europepmc.org/articles/PMC7259516/
Autor:
Matthew H. Spitzer, David R. McIlwain, Gabriela K. Fragiadakis, Garry P. Nolan, Zach Bjornson-Hooper, Deepthi Madhireddy
Animal models are an integral part of the drug development and evaluation process. However, they are unsurprisingly imperfect reflections of humans, and the extent and nature of many immunological differences are unknown. With the rise of targeted an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08297f565f9bcce0868c69db8b915d4
Autor:
Garry P. Nolan, Sean C. Bendall, Zach Bjornson-Hooper, Karen Sachs, Deepthi Madhireddy, Matthew H. Spitzer, Gabriela K. Fragiadakis
Assessing the health and competence of the immune system is central to evaluating vaccination responses, autoimmune conditions, cancer prognosis and treatment. With an increasing number of studies examining immune dysregulation, there is a growing ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7ec0c7b40421ce4ebaffdc4045b9d1
Autor:
Aaron E. Lin, Brian F. Niemeyer, Garry P. Nolan, Kambez H. Benam, David R. McIlwain, Sizun Jiang, Zach Bjornson, Jeffrey Solomon, Jens H. Kuhn, James Logue, Gustavo Palacios
Publikováno v:
Global Virology III: Virology in the 21st Century ISBN: 9783030290214
Risk Group 4 pathogens are a group of often lethal human viruses for which there are no widely available vaccines or therapeutics. These viruses are endemic to specific geographic locations and typically cause relatively infrequent, self-limiting, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5323f9ee9d67268c76fdd4614d3a622a
https://doi.org/10.1007/978-3-030-29022-1_15
https://doi.org/10.1007/978-3-030-29022-1_15
Autor:
Thomas Hart, Sean C. Bendall, Zach Bjornson, Peng Qiu, Michael D. Linderman, Benedict Anchang, Sylvia K. Plevritis, Garry P. Nolan
Publikováno v:
Nature Protocols. 11:1264-1279
High-throughput single-cell technologies provide an unprecedented view into cellular heterogeneity, yet they pose new challenges in data analysis and interpretation. In this protocol, we describe the use of Spanning-tree Progression Analysis of Densi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb29fed8a17842069b45f868485c462
https://doi.org/10.1038/nprot.2016.066
https://doi.org/10.1038/nprot.2016.066
Autor:
Marco Prinz, Bahareh Ajami, Wendy J. Fantl, Garry P. Nolan, Zach Bjornson, Peter Wieghofer, Lawrence Steinman, Andrea Crotti, Nikolay Samusik, Peggy P. Ho
Publikováno v:
Nat Neurosci
Neuroinflammation and neurodegeneration may represent two polarities of brain pathology. Brain myeloid cells, particularly microglia, play key roles in these conditions. Here, we employed single-cell mass cytometry (CyToF) to compare myeloid cell pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df96b4c3ebed1f9d75bde987a52968f
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/89762
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/89762