Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Zabrina L Brumme"'
Autor:
Aniqa Shahid, Bradley R Jones, Julia S W Yang, Winnie Dong, Tawimas Shaipanich, Kathryn Donohoe, Chanson J Brumme, Jeffrey B Joy, Janice M Leung, Zabrina L Brumme
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010613 (2022)
The lung is an understudied site of HIV persistence. We isolated 898 subgenomic proviral sequences (nef) by single-genome approaches from blood and lung from nine individuals on long-term suppressive antiretroviral therapy (ART), and characterized ge
Externí odkaz:
https://doaj.org/article/b8375e0e10134f47b56087abcbfb4199
Autor:
Tomohiro Akahoshi, Hiroyuki Gatanaga, Nozomi Kuse, Takayuki Chikata, Madoka Koyanagi, Naoki Ishizuka, Chanson J Brumme, Hayato Murakoshi, Zabrina L Brumme, Shinichi Oka, Masafumi Takiguchi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009177 (2020)
HIV-1 strains harboring immune escape mutations can persist in circulation, but the impact of selection by multiple HLA alleles on population HIV-1 dynamics remains unclear. In Japan, HIV-1 Reverse Transcriptase codon 135 (RT135) is under strong immu
Externí odkaz:
https://doaj.org/article/cf317fa4c7d4460eb38d3f3929d01091
Autor:
Joanna A Warren, Shuntai Zhou, Yinyan Xu, Matthew J Moeser, Daniel R MacMillan, Olivia Council, Jennifer Kirchherr, Julia M Sung, Nadia R Roan, Adaora A Adimora, Sarah Joseph, JoAnn D Kuruc, Cynthia L Gay, David M Margolis, Nancie Archin, Zabrina L Brumme, Ronald Swanstrom, Nilu Goonetilleke
Publikováno v:
eLife, Vol 9 (2020)
HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus-infected cells. We investigated the patterns of T cell escape varia
Externí odkaz:
https://doaj.org/article/a3918d4bf49a4fd09760d0e0944dc9eb
Autor:
Steven W Jin, Francis M Mwimanzi, Jaclyn K Mann, Mwebesa Bosco Bwana, Guinevere Q Lee, Chanson J Brumme, Peter W Hunt, Jeff N Martin, David R Bangsberg, Thumbi Ndung'u, Zabrina L Brumme, Mark A Brockman
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008813 (2020)
HIV Nef counteracts cellular host restriction factors SERINC3 and SERINC5, but our understanding of how naturally occurring global Nef sequence diversity impacts these activities is limited. Here, we quantify SERINC3 and SERINC5 internalization funct
Externí odkaz:
https://doaj.org/article/478d6961fecb493d9420cae6678958f6
Autor:
Kelsie Brooks, Bradley R Jones, Dario A Dilernia, Daniel J Wilkins, Daniel T Claiborne, Samantha McInally, Jill Gilmour, William Kilembe, Jeffrey B Joy, Susan A Allen, Zabrina L Brumme, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008378 (2020)
The HIV-1 reservoir consists of latently infected cells that persist despite antiretroviral therapy (ART). Elucidating the proviral genetic composition of the reservoir, particularly in the context of pre-therapy viral diversity, is therefore importa
Externí odkaz:
https://doaj.org/article/13bf90a11ad542a4b717846ef1e5870e
Autor:
Nathaniel D Bachtel, Gisele Umviligihozo, Suzanne Pickering, Talia M Mota, Hua Liang, Gregory Q Del Prete, Pramita Chatterjee, Guinevere Q Lee, Rasmi Thomas, Mark A Brockman, Stuart Neil, Mary Carrington, Bosco Bwana, David R Bangsberg, Jeffrey N Martin, Esper G Kallas, Camila S Donini, Natalia B Cerqueira, Una T O'Doherty, Beatrice H Hahn, R Brad Jones, Zabrina L Brumme, Douglas F Nixon, Richard Apps
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007257 (2018)
HIV-1 can downregulate HLA-C on infected cells, using the viral protein Vpu, and the magnitude of this downregulation varies widely between primary HIV-1 variants. The selection pressures that result in viral downregulation of HLA-C in some individua
Externí odkaz:
https://doaj.org/article/fd77a141723449b993740096f7b2aca0
Autor:
Genevieve Rocheleau, Conrado Franco-Villalobos, Natalia Oliveira, Zabrina L Brumme, Melanie Rusch, Jeannie Shoveller, Chanson J Brumme, P Richard Harrigan
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184848 (2017)
Sociodemographic correlates of engagement in human immunodeficiency virus (HIV) care are well studied, however the association with accessing drug resistance testing (DRT) and the development of drug resistance have not been characterized. Between 19
Externí odkaz:
https://doaj.org/article/bf1007ebedc5467e8e2cbe4a42750d0d
Autor:
Damien C Tully, Colin B Ogilvie, Rebecca E Batorsky, David J Bean, Karen A Power, Musie Ghebremichael, Hunter E Bedard, Adrianne D Gladden, Aaron M Seese, Molly A Amero, Kimberly Lane, Graham McGrath, Suzane B Bazner, Jake Tinsley, Niall J Lennon, Matthew R Henn, Zabrina L Brumme, Philip J Norris, Eric S Rosenberg, Kenneth H Mayer, Heiko Jessen, Sergei L Kosakovsky Pond, Bruce D Walker, Marcus Altfeld, Jonathan M Carlson, Todd M Allen
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005619 (2016)
Due to the stringent population bottleneck that occurs during sexual HIV-1 transmission, systemic infection is typically established by a limited number of founder viruses. Elucidation of the precise forces influencing the selection of founder viruse
Externí odkaz:
https://doaj.org/article/247cdda96dd244d4b3f4719243dd631e
Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population.
Autor:
Jiro Katoh, Ai Kawana-Tachikawa, Akihisa Shimizu, Dayong Zhu, Chungyong Han, Hitomi Nakamura, Michiko Koga, Tadashi Kikuchi, Eisuke Adachi, Tomohiko Koibuchi, George F Gao, Zabrina L Brumme, Aikichi Iwamoto
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150397 (2016)
HIV-1 escape from CTL is predictable based on the Human Leukocyte Antigen (HLA) class I alleles expressed by the host. As such, HIV-1 sequences circulating in a population of hosts will harbor escape mutations specific to the HLA alleles of that popu
Externí odkaz:
https://doaj.org/article/9050394358c8447f8a758264c7c84f14
Autor:
Soo-Yon Rhee, Jose Luis Blanco, Michael R Jordan, Jonathan Taylor, Philippe Lemey, Vici Varghese, Raph L Hamers, Silvia Bertagnolio, Tobias F Rinke de Wit, Avelin F Aghokeng, Jan Albert, Radko Avi, Santiago Avila-Rios, Pascal O Bessong, James I Brooks, Charles A B Boucher, Zabrina L Brumme, Michael P Busch, Hermann Bussmann, Marie-Laure Chaix, Bum Sik Chin, Toni T D'Aquin, Cillian F De Gascun, Anne Derache, Diane Descamps, Alaka K Deshpande, Cyrille F Djoko, Susan H Eshleman, Herve Fleury, Pierre Frange, Seiichiro Fujisaki, P Richard Harrigan, Junko Hattori, Africa Holguin, Gillian M Hunt, Hiroshi Ichimura, Pontiano Kaleebu, David Katzenstein, Sasisopin Kiertiburanakul, Jerome H Kim, Sung Soon Kim, Yanpeng Li, Irja Lutsar, Lynn Morris, Nicaise Ndembi, Peng N G Kee, Ramesh S Paranjape, Martine Peeters, Mario Poljak, Matt A Price, Manon L Ragonnet-Cronin, Gustavo Reyes-Terán, Morgane Rolland, Sunee Sirivichayakul, Davey M Smith, Marcelo A Soares, Vincent V Soriano, Deogratius Ssemwanga, Maja Stanojevic, Mariane A Stefani, Wataru Sugiura, Somnuek Sungkanuparph, Amilcar Tanuri, Kok Keng Tee, Hong-Ha M Truong, David A M C van de Vijver, Nicole Vidal, Chunfu Yang, Rongge Yang, Gonzalo Yebra, John P A Ioannidis, Anne-Mieke Vandamme, Robert W Shafer
Publikováno v:
PLoS Medicine, Vol 12, Iss 6, p e1001845 (2015)
Externí odkaz:
https://doaj.org/article/3f1bb08eae2c4266baaa277a93e2465e