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Toward understanding lipid reorganization in RNA lipid nanoparticles in acidic environments.

Autor: Garaizar A; Drug Discovery Sciences, Bayer Pharmaceuticals, Wuppertal 42113, Germany.; Computational Life Science, Bayer Crop Science, Monheim am Rhein 40789, Germany., Díaz-Oviedo D; Drug Discovery Sciences, Bayer Pharmaceuticals, Wuppertal 42113, Germany., Zablowsky N; Lead Discovery, Nuvisan Innovation Campus Berlin, Berlin 13353, Germany., Rissanen S; Chemical and Pharmaceutical Development, Bayer Pharmaceuticals, Turku 20210, Finland., Köbberling J; Drug Discovery Sciences, Bayer Pharmaceuticals, Wuppertal 42113, Germany., Sun J; Chemical and Pharmaceutical Development, Bayer Pharmaceuticals, Berlin 13353, Germany., Steiger C; Chemical and Pharmaceutical Development, Bayer Pharmaceuticals, Berlin 13353, Germany., Steigemann P; Lead Discovery, Nuvisan Innovation Campus Berlin, Berlin 13353, Germany., Mann FA; Chemical and Pharmaceutical Development, Bayer Pharmaceuticals, Berlin 13353, Germany., Meier K; Drug Discovery Sciences, Bayer Pharmaceuticals, Wuppertal 42113, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 05; Vol. 121 (45), pp. e2404555121. Date of Electronic Publication: 2024 Oct 30.