Preparation and evaluation of radioiodinated (iodophenyl)cholines and their morpholinium and piperidinium analogs as myocardial perfusion imaging agents

Autor: Hunter Dh, Chamberlain Mj, Driedger Aa, Zabel Pl, Morrissey G, Y. Zea-Ponce, G. W. Brown

Publikováno v: Journal of Medicinal Chemistry. 29:757-764

A series of nine radioiodinated quaternary ammonium salts related to phenylcholine were synthesized, characterized, and radiolabeled by exchange. These compounds were evaluated as myocardial perfusion imaging agents in mice, pigs, and humans. Mice bi

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https://doi.org/10.1021/jm00155a028

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Cysteine rhenium colloid: a novel radiocolloid for identifying sentinel lymph nodes in breast cancer surgery.

Autor: Kidane B; Department of Surgery, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada., Zabel PL; Department of Medical Imaging, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada; Department of Nuclear Medicine, London Health Sciences Centre, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada., Gupta V; Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom., Whiston C; Department of Surgery, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada; Department of Medical Imaging, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada., Wright F; Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada., Brackstone M; Department of Surgery, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada; Department of Surgery, London Health Sciences Centre, London, Ontario, Canada. Electronic address: muriel.brackstone@lhsc.on.ca.

Publikováno v: Clinical breast cancer [Clin Breast Cancer] 2015 Feb; Vol. 15 (1), pp. e41-5. Date of Electronic Publication: 2014 Aug 15.