Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study.

Autor: Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. francesco.massari@aosp.bo.it., Santoni M; Oncology Unit, Macerata Hospital, via Santa Lucia 2, 62100, Macerata, Italy., Takeshita H; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Okada Y; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Tapia JC; Department of Medical Oncology, Institut d'Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Basso U; Medical Oncology 1 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, 35128, Padova, Italy., Maruzzo M; Medical Oncology 1 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, 35128, Padova, Italy., Scagliarini S; UOC di Oncologia, Azienda Ospedaliera di Rilievo Nazionale Cardarelli di Napoli, Naples, Italy., Büttner T; Department of Urology, University Hospital Bonn (UKB), 53127, Bonn, Germany., Fornarini G; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Myint ZW; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536-0293, USA., Galli L; Oncology Unit 2, University Hospital of Pisa, 56126, Pisa, Italy., Souza VC; Hospital São Rafael Oncologia D'Or, Salvador, BA, Brazil.; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil., Pichler R; Department of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria., De Giorgi U; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Gandur N; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Angel Roffo, Buenos Aires, CABA, Argentina., Lam ET; University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Gilbert D; University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Popovic L; Oncology Institute of Vojvodina, Faculty of Medicine, University Novi Sad, Novi Sad, Serbia., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Mammone G; Department of Radiological, Oncological and Anatomo-Pathological Science, 'Sapienza' University of Rome, Viale Regina Elena 324, 00185, Rome, Italy., Berardi R; Department of Medical Oncology, Università Politecnica Delle Marche, AOU Ospedali Riuniti Delle Marche, Ancona, Italy., Crabb SJ; Southampton Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK., Kemp R; Southampton Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Freitas M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Centro de Pesquisas Oncológicas - CEPON, Florianópolis, SC, Brazil., Luz M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Erasto Gaertner, Curitiba, PR, Brazil., Iacovelli R; Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Calabrò F; Department of Oncology, San Camillo Forlanini Hospital, Rome, Italy., Tural D; Department of Medical Oncology, Bakirköy Dr. SadiKonuk Training and Research Hospital, Tevfik Saglam St. No: 11, Zuhuratbaba District, Bakirkoy, Istanbul, Turkey., Atzori F; Unità di Oncologia Medica, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy., Küronya Z; Department of Genitourinary Medical Oncology and Clinical Pharmacology, National Institute of Oncology, Budapest, Hungary., Chiari R; UOC Oncologia, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Fano, Italy., Campos S; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Centro Oncologico Estatal 'Dr José Luis Barrera Franco' del ISSEMYM, Toluca de Lerdo, Mexico., Caffo O; Medical Oncology Unit, Santa Chiara Hospital, Trento, Italy., Fay AP; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Pontificia Universidade Católica do Rio Grande do Sul - PUCRS, Porto Alegre, RS, Brazil., Kucharz J; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Warsaw, Poland., Zucali PA; Department of Oncology, IRCCS Humanitas Research Hospital, Rozzano - Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Rinck JA; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital AC Camargo, São Paulo, SP, Brazil., Zeppellini A; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Bastos DA; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Department of Oncology, Hospital Sírio-Libanês, São Paulo, SP, Brazil., Aurilio G; Division of Cancer Prevention and Genetics, IEO European Institute of Oncology IRCCS, Milan, Italy., Mota A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clínica AMO, Salvador, BA, Brazil., Trindade K; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncologia D'Or, Fortaleza, CE, Brazil., Ortega C; ASLCN2 Alba-Bra, Ospedale Michele E Pietro Ferrero, Verduno, CN, Italy., Sade JP; Instituto Alexander Fleming, Buenos Aires, CABA, Argentina., Rizzo M; Division of Medical Oncology, A.O.U. Consorziale Policlinico Di Bari, Piazza G. Cesare 11, 70124, Bari, Italy., Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Vau N; Urologic Oncology, Champalimaud Clinical Center, 1400-038, Lisbon, Portugal., Giannatempo P; Dipartimento di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy., Barillas A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinicas Medicas Especializadas NUCARE, Guatemala City, Guatemala., Monteiro FSM; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Sirio-Libanês, Brasília, DF, Brazil., Dauster B; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Sao Rafael, Salvador, BA, Brazil., Mennitto A; Department of Medical Oncology, 'Maggiore Della Carità' University Hospital, 28100, Novara, Italy., Nogueira L; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brazil., de Carvalho Fernandes R; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Santa Casa de Sao Paulo, São Paulo, SP, Brazil., Seront E; Department of Medical Oncology, Centre Hospitalier de Jolimont, Haine Saint Paul, Belgium., Aceituno LG; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinica Medica Especializada en Oncologia Medica, Guatemala City, Guatemala., Grillone F; UO Oncologia Azienda Ospedaliera Universitaria Renato Dulbecco PO Pugliese Ciaccio Catanzaro, Catanzaro, Italy., Cutuli HJ; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Sirio Libanes, Buenos Aires, CABA, Argentina., Fernandez M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Fundacion Centro Oncologico de Integracion Regional - COIR, Mendoza, Argentina., Bassanelli M; Medical Oncology 1-IRCCS Regina Elena National Cancer Institute, Rome, Italy., Kopp RM; Clinical Oncology, Sociedad de Oncología y Hematología del Cesar, Valledupar, Colombia., Roviello G; Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy., Abahssain H; Medicine and Pharmacy Faculty, National Institute of Oncology, Medical Oncology Unit, Mohamed V University, Rabat, Morocco., Procopio G; Dipartimento di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.; Oncologia Medica, Ospedale Maggiore di Cremona, Cremona, Italy., Milella M; Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy., Kopecky J; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Martignetti A; Dipartimento Oncologico USL Sud-Est Toscana-Area Senese, Località Campostaggia S.N.C, 53036, Poggibonsi, Italy., Messina C; Oncology Unit, A.R.N.A.S. Civico, Palermo, Italy., Caitano M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital do Câncer Porto Dias - Rede Mater Dei de Saúde, Belém, PA, Brazil., Inman E; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; ONCOR Life Medical Center, Saltillo, Mexico., Kanesvaran R; National Cancer Centre Singapore, Singapore, Singapore., Herchhorn D; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Instituto D'Or de Ensino e Pesquisa, Rio de Janeiro, RJ, Brazil., Santini D; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, University of Rome, SapienzaRome, Italy., Bamias A; 2nd Propaedeutic Department of Internal Medicine, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Bisonni R; UOC Oncologia Medica, Ospedale A. Murri, Fermo, Italy., Mosca A; Oncology, Candiolo Cancer Institute, IRCCS-FPO, 10060, Turin, Italy., Morelli F; Medical Oncology Unit, Gemelli Molise Hospital, Università Cattolica del Sacro Cuore, Campobasso, Italy., Maluf F; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Beneficencia Portuguesa de São Paulo, São Paulo, SP, Brazil., Soares A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Nunes F; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinica de Oncologia - Clion, Salvador, BA, Brazil., Pinto A; Medical Oncology Department, La Paz University Hospital, Madrid, Spain., Zgura A; Department of Oncology-Radiotherapy, Prof. Dr. Alexandru Trestioreanu Institute of Oncology, Carol Davila; University of Medicine and Pharmacy, Bucharest, Romania., Incorvaia L; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Via del Vespro 129, 90127, Palermo, Italy., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates., Zabalza IO; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Landmesser J; Klinik für Urologie, Ratzeburger Allee 160, 23538, Lübeck, Germany., Rizzo A; Struttura Semplice Dipartimentale di Oncologia Medica per la Presa in Carico Globale del Paziente Oncologico 'Don Tonino Bello', I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy., Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Marchetti A; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Rosellini M; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Sorgentoni G; Oncology Unit, Macerata Hospital, via Santa Lucia 2, 62100, Macerata, Italy., Battelli N; Oncology Unit, Macerata Hospital, via Santa Lucia 2, 62100, Macerata, Italy., Buti S; Medical Oncology Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy., Porta C; Chair of Oncology, Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy., Bellmunt J; Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2024 Apr 18; Vol. 73 (6), pp. 106. Date of Electronic Publication: 2024 Apr 18.

Use of concomitant proton pump inhibitors, statins or metformin in patients treated with pembrolizumab for metastatic urothelial carcinoma: data from the ARON-2 retrospective study.

Autor: Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital Pilsen, Charles University, Alej Svobody 80, 304 60, Pilsen, Czech Republic. fialao@fnplzen.cz.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic. fialao@fnplzen.cz., Buti S; Department of Medicine and Surgery, University Hospital of Parma, Parma, Italy.; Medical Oncology Unit, University Hospital of Parma, Parma, Italy., Takeshita H; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Okada Y; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Via Albertoni - 15, Bologna, Italy., Palacios GA; Department of Medical Oncology, Institutd' Investigació Biomèdica Sant Pau, Hospital de La Santa Creu I Sant Pau, Barcelona, Spain., Dionese M; Oncology 1 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, 35128, Padua, Italy., Scagliarini S; UOC Di Oncologia, Azienda Ospedaliera Di Rilievo Nazionale Cardarelli Di Napoli, Naples, Italy., Büttner T; Department of Urology, University Hospital Bonn (UKB), 53127, Bonn, Germany., Fornarini G; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Myint ZW; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536-0293, USA., Galli L; Oncology Unit 2, University Hospital of Pisa, 56126, Pisa, Italy., Souza VC; Hospital São Rafael Oncologia D'Or, Salvador, BA, Brazil.; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil., Pichler R; Department of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria., De Giorgi U; Department of Medical Oncology, IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Quiroga MNG; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Angel Roffo, Buenos Aires, CABA, Argentina., Gilbert D; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, CO, USA., Popovic L; Oncology Institute of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Mammone G; Department of Radiological, Oncological and Anatomo-Pathological Science, Sapienza University of Rome, Viale Regina Elena 324, 00185, Rome, Italy., Berardi R; Department of Medical Oncology, Università Politecnica Delle Marche, AOU Ospedali Riuniti Delle Marche, Ancona, Italy., Crabb SJ; Southampton Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón Y Cajal, Madrid, Spain., Freitas M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Centro de Pesquisas Oncológicas - CEPON, Florianópolis, SC, Brazil., Luz M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Erasto Gaertner, Curitiba, PR, Brazil., Iacovelli R; Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Calabrò F; Department of Oncology, San Camillo Forlanini Hospital, Rome, Italy., Tural D; Department of Medical Oncology, Bakirköy Dr. Sadi Konuk Training and Research Hospital, Zuhuratbaba District, Tevfik Saglam St. No: 11, Bakirkoy, Istanbul, Turkey., Atzori F; Unità Di Oncologia Medica, Azienda Ospedaliero Universitaria Di Cagliari, Cagliari, Italy., Küronya Z; Department of Genitourinary Medical Oncology and Clinical Pharmacology, National Institute of Oncology, Budapest, Hungary., Chiari R; UOC Oncologia, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Fano, Italy., Campos S; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Centro Oncologico Estatal 'Dr José Luis Barrera Franco' del ISSEMYM, Toluca de Lerdo, Mexico., Caffo O; Medical Oncology Unit, Santa Chiara Hospital, Trento, Italy., Fay AP; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Pontificia Universidade Católica Do Rio Grande Do Sul - PUCRS, Porto Alegre, RS, Brazil., Kucharz J; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Zucali PA; Department of Oncology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Rinck JA; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital AC Camargo, São Paulo, SP, Brazil., Zeppellini A; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Bastos DA; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Department of Oncology, Hospital Sírio-Libanês, São Paulo, SP, Brazil., Aurilio G; Medical Oncology Division of Urogenital and Head and Neck Tumours, IEO, European Institute of Oncology IRCCS, Milan, Italy., Mota A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clínica AMO, Salvador, BA, Brazil., Trindade K; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncologia D'Or, Fortaleza, CE, Brazil., Ortega C; Division of Oncology, Institute for Cancer Research and Treatment, Asl Cn2 Alba-Brà, 12051, Alba-Brà, Italy., Sade JP; Instituto Alexander Fleming, Buenos Aires, CABA, Argentina., Rizzo M; Division of Medical Oncology, A.O.U. Consorziale Policlinico Di Bari, Piazza G. Cesare 11, 70124, Bari, Italy., Vau N; Urologic Oncology, Champalimaud Clinical Center, 1400-038, Lisbon, Portugal., Giannatempo P; Dipartimento Di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy., Barillas A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinicas Medicas Especializadas NUCARE, Guatemala City, Guatemala., Monteiro FSM; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Santa Lucia, SHLS 716 Cj. C, Brasília, DF, 70390-700, Brazil., Dauster B; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Sao Rafael, Salvador, BA, Brazil., Cattrini C; Department of Medical Oncology, 'Maggiore Della Carità' University Hospital, 28100, Novara, Italy., Nogueira L; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brazil., de Carvalho Fernandes R; Hospital Santa Casa de Sao Paulo, São Paulo, SP, Brazil., Seront E; Department of Medical Oncology, Centre Hospitalier de Jolimont, Haine Saint Paul, Belgium., Aceituno LG; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinica Medica Especializada en Oncologia Medica, Guatemala City, Guatemala., Grillone F; SOC Oncologia Medica, Azienda Ospedaliera 'Pugliese -Ciaccio', Catanzaro, Italy., Cutuli HJ; Hospital Sirio Libanes, Buenos Aires, CABA, Argentina., Fernandez M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Fundacion Centro Oncologico de Integracion Regional - COIR, Mendoza, Argentina., Bassanelli M; Medical Oncology, 1-IRCCS Regina Elena National Cancer Institute, Rome, Italy., Roviello G; Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy., Abahssain H; Medical Oncology Unit, National Institute of Oncology, Medicine and Pharmacy Faculty, Mohammed V University, Rabat, Morocco., Procopio G; Dipartimento Di Oncologia Medica, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.; Oncologia Medica, Ospedale Maggiore Di Cremona, Cremona, Italy., Milella M; Section of Oncology, Department of Medicine, School of Medicine and Verona University Hospital Trust, University of Verona, Verona, Italy., Kopecky J; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Martignetti A; UOC Oncologia Medica, Ospedale Dell'alta Val D'Elsa - Usl sud est Toscana Area Senese, Poggibonsi, Italy., Messina C; Oncology Unit, A.R.N.A.S. Civico, Palermo, Italy., Caitano M; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital do Câncer Porto Dias - Rede Mater Dei de Saúde, Belém, PA, Brazil., Inman E; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; ONCOR Life Medical Center, Saltillo, Mexico., Kanesvaran R; National Cancer Centre Singapore, Singapore, Republic of Singapore., Herchenhorn D; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Instituto D'Or de Ensino E Pesquisa, Rio de Janeiro, RJ, Brazil., Santini D; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy., Manneh R; Clinical Oncology, Sociedad de Oncología Y Hematología del Cesar, Valledupar, Colombia., Bisonni R; UOC Oncologia Medica, Ospedale A. Murri, Fermo, Italy., Zakopoulou R; 2nd Propaedeutic Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Mosca A; Department of Oncology Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Turin, Italy., Morelli F; Medical Oncology Unit, Gemelli Molise Hospital, Università Cattolica del Sacro Cuore, Campobasso, Italy., Maluf F; Hospital Beneficencia Portuguesa de São Paulo, São Paulo, SP, Brazil.; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Soares A; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.; Centro Paulista de Oncologia/Oncoclinicas, Sao Paulo, Brazil., Nunes F; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Clinica de Oncologia - Clion, Salvador, BA, Brazil., Pinto A; Medical Oncology Department, La Paz University Hospital, Madrid, Spain., Zgura A; Department of Oncology-Radiotherapy, Prof. Dr. Alexandru Trestioreanu Institute of Oncology, University of Medicine and Pharmacy, Bucharest, Romania., Incorvaia L; Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates., Zabalza IO; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Landmesser J; Klinik Für Urologie, Ratzeburger Allee 160, 23538, Lübeck, Germany., Rizzo A; Struttura Semplice Dipartimentale Di Oncologia Medica Per La Presa in Carico Globale del Paziente Oncologico 'Don Tonino Bello', I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy., Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Via Albertoni - 15, Bologna, Italy., Sorgentoni G; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy., Battelli N; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy., Porta C; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy., Bellmunt J; Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Santoni M; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2023 Nov; Vol. 72 (11), pp. 3665-3682. Date of Electronic Publication: 2023 Sep 07.

Real-world effectiveness of pembrolizumab as first-line therapy for cisplatin-ineligible patients with advanced urothelial carcinoma: the ARON-2 study.

Autor: Santoni M; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy. mattymo@alice.it., Myint ZW; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536-0293, USA., Büttner T; Department of Urology, University Hospital Bonn (UKB), 53127, Bonn, Germany., Takeshita H; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Okada Y; Department of Urology, Saitama Medical Center, Saitama Medical University, Saitama, Japan., Lam ET; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, CO, USA., Gilbert D; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, CO, USA., Küronya Z; Department of Genitourinary Medical Oncology and Clinical Pharmacology, National Institute of Oncology, Budapest, Hungary., Tural D; Department of Medical Oncology, Bakirköy Dr. Sadi Konuk Training and Research Hospital, Zuhuratbaba District, Tevfik Saglam St. No: 11, Bakirkoy, Istanbul, Turkey., Pichler R; Department of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Crabb SJ; Southampton Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK., Kemp R; Southampton Experimental Cancer Medicine Centre, University of Southampton, Southampton, UK., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Via Albertoni - 15, Bologna, Italy., Scagliarini S; UOC di Oncologia, Azienda Ospedaliera di Rilievo Nazionale Cardarelli di Napoli, Naples, Italy., Iacovelli R; Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Vau N; Urologic Oncology, Champalimaud Clinical Center, 1400-038, Lisbon, Portugal., Basso U; Medical Oncology 1 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, 35128, Padua, Italy., Maruzzo M; Medical Oncology 1 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, 35128, Padua, Italy., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Galli L; Oncology Unit 2, University Hospital of Pisa, 56126, Pisa, Italy., Bamias A; 2nd Propaedeutic Department of Internal Medicine, School of Medicine, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece., De Giorgi U; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Zucali PA; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Department of Oncology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Rizzo M; Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Piazza G. Cesare 11, 70124, Bari, Italy., Seront E; Department of Medical Oncology, Centre Hospitalier de Jolimont, Haine Saint Paul, Belgium., Popovic L; Oncology Institute of Vojvodina, Faculty of Medicine, University Novi Sad, Novi Sad, Serbia., Caffo O; Medical Oncology Unit, Santa Chiara Hospital, Trento, Italy., Buti S; Medical Oncology Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy., Kanesvaran R; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Kopecky J; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Kucharz J; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Zeppellini A; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Landmesser J; Klinik für Urologie, Ratzeburger Allee 160, 23538, Lübeck, Germany., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates., Giannatempo P; Dipartimento di Oncologia Medica, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Rizzo A; Struttura Semplice Dipartimentale di Oncologia Medica per la Presa in Carico Globale del Paziente Oncologico 'Don Tonino Bello', I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Bari, Italy., Zabalza IO; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Monteiro FSM; Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Santa Lucia, SHLS 716 Cj. C, Brasília, DF, 70390-700, Brazil., Battelli N; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy., Calabrò F; Department of Oncology, San Camillo Forlanini Hospital, Rome, Italy., Porta C; Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Piazza G. Cesare 11, 70124, Bari, Italy.; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2023 Sep; Vol. 72 (9), pp. 2961-2970. Date of Electronic Publication: 2023 May 29.

Global Real-World Outcomes of Patients Receiving Immuno-Oncology Combinations for Advanced Renal Cell Carcinoma: The ARON-1 Study.

Autor: Santoni M; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy. mattymo@alice.it., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, Bologna, Italy., Myint ZW; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536-0293, USA., Iacovelli R; Oncologia Medica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Pichler M; Division of Oncology, Department of Internal Medicine, Medical University of Graz, Augenbruggerplatz 15, 8010, Graz, Austria., Basso U; Oncology 3 Unit, Department of Oncology, Istituto Oncologico Veneto IOV IRCCS, Padua, Italy., Kopecky J; Department of Clinical Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Kucharz J; Department of Uro-oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Buti S; Medical Oncology Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy., Rizzo M; Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Piazza G. Cesare 11, 70124, Bari, Italy., Galli L; Oncology Unit 2, University Hospital of Pisa, 56126, Pisa, Italy., Büttner T; Department of Urology, University Hospital Bonn (UKB), 53127, Bonn, Germany., De Giorgi U; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Kanesvaran R; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Zucali PA; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Department of Oncology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Fornarini G; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bourlon MT; Hematology and Oncology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Scagliarini S; UOC di Oncologia, Azienda Ospedaliera di Rilievo Nazionale Cardarelli di Napoli, Naples, Italy., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Aurilio G; Medical Oncology Division of Urogenital and Head and Neck Tumours, IEO, European Institute of Oncology IRCCS, Milan, Italy., Matrana MR; Department of Internal Medicine, Hematology/Oncology, Ochsner Medical Center, New Orleans, LA, USA., Pichler R; Department of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria., Cattrini C; Department of Medical Oncology, 'Maggiore della Carità' University Hospital, 28100, Novara, Italy., Büchler T; Department of Oncology, First Faculty of Medicine, Charles University, Thomayer University Hospital, 14059, Prague, Czech Republic., Seront E; Department of Medical Oncology, Centre Hospitalier de Jolimont, Haine Saint Paul, Belgium., Calabrò F; Department of Oncology, San Camillo Forlanini Hospital, Rome, Italy., Pinto A; Medical Oncology Department, La Paz University Hospital, Madrid, Spain., Berardi R; Department of Medical Oncology, Università Politecnica delle Marche, AOU Ospedali Riuniti delle Marche, Ancona, Italy., Zgura A; Department of Oncology-Radiotherapy, Prof. Dr. Alexandru Trestioreanu Institute of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Mammone G; Department of Radiological, Oncological and Anatomo-Pathological Science, 'Sapienza' University of Rome, Viale Regina Elena 324, 00185, Rome, Italy., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates., Atzori F; Unità di Oncologia Medica, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy., Chiari R; UOC Oncologia, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Tuscany, Italy., Bamias A; 2nd Propaedeutic Department of Internal Medicine, School of Medicine, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Caffo O; Medical Oncology Unit, Santa Chiara Hospital, Trento, Italy., Procopio G; Dipartimento di Oncologia Medica, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Oncologia Medica, Ospedale Maggiore di Cremona, Cremona, Italy., Bassanelli M; Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Merler S; Section of Oncology, Department of Medicine, University of Verona School of Medicine, Verona University Hospital Trust, Verona, Italy., Messina C; Oncology Unit, A.R.N.A.S. Civico, Palermo, Italy., Küronya Z; Department of Genitourinary Medical Oncology and Clinical Pharmacology, National Institute of Oncology, Budapest, Hungary., Mosca A; Oncology, Candiolo Cancer Institute, IRCCS-FPO, 10060, Turin, Italy., Bhuva D; Department of Medical Oncology, Army Hospital Research and Referral, New Delhi, India., Vau N; Urologic Oncology, Champalimaud Clinical Center, 1400-038, Lisbon, Portugal., Incorvaia L; Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy., Rebuzzi SE; Medical Oncology, Ospedale San Paolo, 17100, Savona, Italy.; Department of Internal Medicine and Medical Specialties (Di.M.I.), University of Genoa, Genoa, Italy., Roviello G; Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy., Zabalza IO; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Rizzo A; Struttura Semplice Dipartimentale di Oncologia Medica per la Presa in Carico Globale del Paziente Oncologico 'Don Tonino Bello', I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124, Bari, Italy., Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, Bologna, Italy., Sorgentoni G; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy., Monteiro FSM; Latin American Cooperative Oncology Group-LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Santa Lucia, SHLS 716 Cj. C, Brasília, DF, 70390-700, Brazil., Montironi R; Molecular Medicine and Cell Therapy Foundation, Polytechnic University of the Marche Region, 60126, Ancona, Italy., Battelli N; Oncology Unit, Macerata Hospital, Via Santa Lucia 2, 62100, Macerata, Italy., Porta C; Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Piazza G. Cesare 11, 70124, Bari, Italy.; Chair of Oncology, Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.

Publikováno v: Targeted oncology [Target Oncol] 2023 Jul; Vol. 18 (4), pp. 559-570. Date of Electronic Publication: 2023 Jun 27.

Statins and renal cell carcinoma: Antitumor activity and influence on cancer risk and survival.

Autor: Santoni M; Oncology Unit, Macerata Hospital, via Santa Lucia 2, 62100 Macerata, Italy. Electronic address: mattymo@alice.it., Monteiro FSM; Latin American Cooperative Oncology Group - LACOG, Brazil; Oncology and Hematology Department, Hospital Santa Lucia, SHLS 716 Cj. C, Brasília, DF 70390-700, Brazil., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni - 15, Bologna, Italy., Abahssain H; Medicine and Pharmacy Faculty, National Institute of Oncology, Medical Oncology Unit, Mohamed V University, Rabat, Morocco., Aurilio G; Medical Oncology Division of Urogenital and Head and Neck Tumours, IEO, European Institute of Oncology IRCCS, Milan, Italy., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Myint ZW; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536-0293, USA; Division of Medical Oncology, University of Kentucky, Lexington, KY, USA., Zabalza IO; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Battelli N; Oncology Unit, Macerata Hospital, via Santa Lucia 2, 62100 Macerata, Italy., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain.

Publikováno v: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2022 Aug; Vol. 176, pp. 103731. Date of Electronic Publication: 2022 Jun 17.