Zobrazeno 1 - 10
of 132
pro vyhledávání: '"ZONG-GEN PENG"'
Autor:
Hu Li, Xue-Kai Wang, Mei Tang, Lei Lei, Jian-Rui Li, Han Sun, Jing Jiang, Biao Dong, Hong-Ying Li, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTGut microbiota plays an essential role in the progression of nonalcoholic fatty liver disease (NAFLD), making the gut-liver axis a potential therapeutic strategy. Bacteroides genus, the enriched gut symbionts, has shown promise in treating fa
Externí odkaz:
https://doaj.org/article/ab3b458b8c954c298ea7473b9b368c59
Autor:
Han Sun, Xue-Kai Wang, Jian-Rui Li, Mei Tang, Hu Li, Lei Lei, Hong-Ying Li, Jing Jiang, Jia-Yu Li, Biao Dong, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The cell adhesion between leukocytes and endothelial cells plays an important balanced role in the pathophysiological function, while excessive adhesion caused by etiological agents is associated with the occurrence and development of many acute and
Externí odkaz:
https://doaj.org/article/591629a84ae74f238cc4a416a08f0d00
Autor:
Hu Li, Nan-Nan Liu, Jian-Rui Li, Biao Dong, Mei-Xi Wang, Jia-Li Tan, Xue-Kai Wang, Jing Jiang, Lei Lei, Hong-Ying Li, Han Sun, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nonalcoholic fatty liver disease (NAFLD), ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), is a liver disease worldwide without approved therapeutic drugs. Anti-inflammatory and hepatoprotective drug bicyclol and multi-pharmacolo
Externí odkaz:
https://doaj.org/article/e6cbf5bb267341f4972f2dfeb692ca96
Autor:
Xue-Kai Wang, Zong-Gen Peng
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Nonalcoholic fatty liver disease (NAFLD), especially its advanced stage nonalcoholic steatohepatitis (NASH), has become a threatened public health problem worldwide. However, no specific drug has been approved for clinical use to treat patients with
Externí odkaz:
https://doaj.org/article/64e8b028415043e1887fd5fcdd6bfa5a
Publikováno v:
BMJ Open, Vol 10, Iss 12 (2020)
Objective Non-alcoholic fatty liver disease (NAFLD) is a global epidemic without effective therapeutic agents in the clinic. This meta-analysis aimed to assess the efficacy of the marketed hepatoprotectant bicyclol at improving blood biomarkers in pa
Externí odkaz:
https://doaj.org/article/a7a24027dd294fa7a76968ae32782122
Autor:
Sheng Tang, Zong-Gen Peng, Ying-Hong Li, Xin Zhang, Tian-Yun Fan, Jian-Dong Jiang, Yan-Xiang Wang, Dan-Qing Song
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-13 (2017)
Abstract Background 12N-benzyl matrinic acid analogues had been identified to be a novel scaffold of anti-HCV agents with a specific mechanism, and the representative compound 1 demonstrated a moderate anti-HCV activity. The intensive structure–act
Externí odkaz:
https://doaj.org/article/3d38c76e33cd4b5ab6cb5f49deb458c4
Autor:
Hu Li, Jian-Rui Li, Meng-Hao Huang, Jin-Hua Chen, Xiao-Qin Lv, Li-Li Zou, Jia-Li Tan, Biao Dong, Zong-Gen Peng, Jian-Dong Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Treatment with direct-acting antivirals (DAAs) cures most patients infected with hepatitis C virus (HCV) in the real world. However, some patients, especially those with the underlying advanced liver disease, have a limited reduction of liver injury
Externí odkaz:
https://doaj.org/article/b94f0029016a49858255646f895beb5a
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Autophagy-related 10 (ATG10) is essential for autophagy since it promotes ATG5-ATG12 complex formation. Our previous study found that there are two isoforms of the ATG10 protein, ATG10 (a longer one) and ATG10S, which have identical sequences except
Externí odkaz:
https://doaj.org/article/9683e3ce7abb4a13a0a20c0fa0ef9f3b
Autor:
Mei-Xi Wang, Zong-Gen Peng
Publikováno v:
Pharmacology & Therapeutics. 246:108428
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0d8b913495506a5ecb044abe556a0a
https://doi.org/10.1016/j.pharmthera.2023.108428
https://doi.org/10.1016/j.pharmthera.2023.108428
Autor:
Da-Jun Zhang, Wen-Fang Sun, Zhao-Jin Zhong, Rong-Mei Gao, Hong Yi, Yu-Huan Li, Zong-Gen Peng, Zhuo-Rong Li
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 925-939 (2014)
A series of novel unsaturated five-membered benzo-heterocyclic amine derivatives were synthesized and assayed to determine their in vitro broad-spectrum antiviral activities. The biological results showed that most of our synthesized compounds exhibi
Externí odkaz:
https://doaj.org/article/3c9910e844af4218b4e5c2c3d9b06fa2