Zobrazeno 1 - 10
of 63
pro vyhledávání: '"ZNF521"'
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37528- (2024)
Zinc finger protein 521 (ZNF521) participates in the self-renewal of hematopoietic stem cells, and its abnormal expression has been implicated to promote leukemia. However, the specific role of ZNF521 in leukemia has not been fully understood. In thi
Externí odkaz:
https://doaj.org/article/009a8c07fc6f41c6b84ed0837f1b9ed5
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 3, Pp 244-253 (2023)
Abstract Although the incidence and death rates of gastric cancer (GC) are decreasing, approximately one million new cases and 800,000 GC‐related deaths were reported worldwide in 2018. Currently, the oncogenesis of GC remains unclear, and the dema
Externí odkaz:
https://doaj.org/article/86832054458e4287a295fda36f02c681
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14755 (2023)
The human zinc finger protein 521 (ZNF521) is a co-transcriptional factor with multiple recognized regulatory functions in a range of normal, cancer and stem cell compartments. ZNF521 regulates proliferation, progression and CSC (cancer stem cell) co
Externí odkaz:
https://doaj.org/article/a8d68d981b49409291467022982c98dd
Autor:
Emanuela Chiarella, Annamaria Aloisio, Stefania Scicchitano, Heather Mandy Bond, Maria Mesuraca
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8461 (2021)
Powerful bioinformatics tools have provided a wealth of novel miRNA–transcription factor networks crucial in controlling gene regulation. In this review, we focus on the biological functions of miRNAs targeting ZNF521, explaining the molecular mech
Externí odkaz:
https://doaj.org/article/344167d770ba4321bf84c1419435894b
Akademický článek
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Akademický článek
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Autor:
Emanuela Chiarella, Annamaria Aloisio, Stefania Scicchitano, Valeria Lucchino, Ylenia Montalcini, Olimpio Galasso, Manfredi Greco, Giorgio Gasparini, Maria Mesuraca, Heather M. Bond, Giovanni Morrone
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 4095 (2018)
Human adipose-derived stem cells (hADSCs) are multipotent mesenchymal cells that can differentiate into adipocytes, chondrocytes, and osteocytes. During osteoblastogenesis, the osteoprogenitor cells differentiate into mature osteoblasts and synthesiz
Externí odkaz:
https://doaj.org/article/c125e41d4ad34745901eb8fdbce9f57c
Publikováno v:
Journal of Cancer
Zinc finger protein 521 (ZNF521) plays an important role in the tumor development and process. However, its regulatory role in hepatocellular carcinoma (HCC) remains unclear. In this study, we demonstrated for the first time that ZNF521 mRNA and prot
Autor:
Giovanni Morrone, Fabrizio Bianchi, Bruna Codispoti, Enrico De Smaele, Heather M. Bond, Valeria Lucchino, Pietro Zoppoli, Annamaria Aloisio, Valentina Melocchi, Stefania Scicchitano, Emanuela Chiarella, Ylenia Montalcini, Marco Giordano, Maria Mesuraca
Publikováno v:
Cell Death and Disease, Vol 10, Iss 10, Pp 1-16 (2019)
Cell Death & Disease
Cell death & disease 10(10), 715 (2019). doi:10.1038/s41419-019-1946-x
Cell Death & Disease
Cell death & disease 10(10), 715 (2019). doi:10.1038/s41419-019-1946-x
ZNF521 is a transcription co-factor with recognized regulatory functions in haematopoietic, osteo-adipogenic and neural progenitor cells. Among its diverse activities, ZNF521 has been implicated in the regulation of medulloblastoma (MB) cells, where