Zobrazeno 1 - 10
of 43
pro vyhledávání: '"ZNF202"'
Publikováno v:
REPORTS. 2:46-53
Cardiovascular diseases, in particular myocardial infarction, are one of the most common causes of death in the world. To date, the risk assessment strategy infarction and post-infarction complications represent a significant problem sensitivity and
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Endothelial lipase (LIPG) and zinc finger protein 202 (ZNF202) are two pivotal genes in HDL metabolism, and therefore, it is important to understand the impact their sequence variants may have on HDL cholesterol levels. We resequenced the entire both
Externí odkaz:
https://doaj.org/article/2fd0e5af60a54c08bdad71ca6b42bf08
Autor:
Mette Refstrup, Karin M. Hansen, Maja S. Petersen, Vibeke Blaabjerg, Viviana Ystaas, Rolf V. Andersen, Peter B. Nielsen
Publikováno v:
Gene. 507:79-84
Classical hereditary hemochromatosis involves the HFE -gene and diagnostic analysis of the DNA variants HFE p.C282Y (c.845G > A; rs1800562) and HFE p.H63D (c.187C > G; rs1799945). The affected protein alters the iron homeostasis resulting in iron ove
Autor:
Maria C. A. Stene, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Peer Grande, Ruth Frikke-Schmidt, Peter Schnohr
Publikováno v:
Journal of the American College of Cardiology. 52(5):369-377
Objectives This study was designed to test the hypotheses that single nucleotide polymorphisms (SNPs), in zinc finger protein 202 (ZNF202), predict severe atherosclerosis and ischemic heart disease (IHD). Background ZNF202 is a transcriptional repres
Autor:
Rolf Steffensen, Peter Schnohr, Ruth Frikke-Schmidt, Maria C. A. Stene, Børge G. Nordestgaard, Anne Tybjærg-Hansen
Publikováno v:
Atherosclerosis. 188:43-50
Objective Zinc Finger Protein 202 (ZNF202) is a transcriptional repressor of genes affecting the vascular endothelium as well as lipid metabolism. A phenotype associated with genetic variation in ZNF202 is presently unknown. We tested the hypothesis
Autor:
Robert M. Babb, Benjamin R. Bowen
Publikováno v:
Biochemical Journal. 370:719-727
Peroxisome-proliferator-activated receptors (PPARs), members of the nuclear hormone receptor superfamily, play an important role in the regulation of lipid metabolism and energy homoeostasis. In a yeast two-hybrid experiment using the zinc-finger tra
Autor:
Seemann, Andrea Julia
Eine zentrale Rolle bei der Entstehung von Arteriosklerose und ihren Folgeerkrankungen spielen Veränderungen im Lipidstoffwechsel. In diesen Metabolismus greifen eine Vielzahl von Transkriptionsfaktoren, wie zum Beispiel die nukleären Hormonrezepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a00cb91fde2a7e0b7dc1b2041839fb0
Autor:
Benjamin R. Bowen, Patricia Ormonde-Hanson, Mark H. Skolnick, Susanne Wagner, Dennis G. Ballinger, Mike Chen, Robert Kehrer, Michael Beluch, Christian Honer, Mark A. Hess, Michael Frodsham, Christoph Schumacher, Jennifer Malandro, Heping Hu
Publikováno v:
Journal of Biological Chemistry. 275:15685-15690
The ZNF202 gene resides in a chromosomal region linked genetically to low high density lipoprotein cholesterol in Utah families. Here we show that the ZNF202 gene product is a transcriptional repressor that binds to elements found predominantly in ge
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 3 (2012)
Frontiers in Genetics, Vol 3 (2012)
Endothelial lipase (LIPG) and zinc finger protein 202 (ZNF202) are two pivotal genes in high density lipoprotein (HDL metabolism). We sought to determine their genetic contribution to variation in HDL-cholesterol levels by comprehensive resequencing
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