Myeloperoxidase enhances the migration of human choriocarcinoma JEG-3 cells1

Autor: ZN. Mihalic, T. Kloimböck, N. Cosic-Mujkanovic, P. Valadez-Cosmes, K. Maitz, O. Kindler, C. Wadsack, A. Heinemann, G. Marsche, M. Gauster, J. Pollheimer, J. Kargl

Myeloperoxidase (MPO) is one of the most abundant proteins in neutrophil granules. It catalyzes the production of reactive oxygen species, which are important in inflammation and immune defense. MPO also binds to several proteins, lipids, and DNA to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc1002a42f58b2dbc360893986a16e4d
https://doi.org/10.1101/2023.01.28.526039

Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data.

Autor: Einhaus J; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany., Gaudilliere DK; Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Hedou J; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Feyaerts D; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Ozawa MG; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Sato M; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Ganio EA; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tsai AS; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Stelzer IA; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Bruckman KC; Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Amar JN; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Sabayev M; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Bonham TA; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gillard J; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Diop M; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Cambriel A; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Mihalic ZN; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Valdez T; Division of Pediatrics, Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, USA., Liu SY; Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Division of Sleep Surgery, Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, USA., Feirrera L; Department of Oral and Maxillofacial Surgery, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA., Lam DK; Department of Oral and Maxillofacial Surgery, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA., Sunwoo JB; Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, USA., Schürch CM; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany., Gaudilliere B; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Han X; Department of Biomedical Sciences, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA.

Publikováno v: IScience [iScience] 2023 Nov 20; Vol. 26 (12), pp. 108486. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).

Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival.

Autor: Cosic-Mujkanovic N; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Valadez-Cosmes P; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Maitz K; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Lueger A; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Mihalic ZN; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Runtsch MC; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Kienzl M; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria., Davies MJ; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, DK-2200 Copenhagen, Denmark., Chuang CY; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, DK-2200 Copenhagen, Denmark., Heinemann A; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria., Schicho R; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria., Marsche G; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria., Kargl J; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.; BioTechMed-Graz, 8010 Graz, Austria.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Aug 09; Vol. 12 (8). Date of Electronic Publication: 2023 Aug 09.

Myeloperoxidase: Growing importance in cancer pathogenesis and potential drug target.

Autor: Valadez-Cosmes P; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria., Raftopoulou S; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria., Mihalic ZN; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria., Marsche G; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria., Kargl J; Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria. Electronic address: julia.kargl@medunigraz.at.

Publikováno v: Pharmacology & therapeutics [Pharmacol Ther] 2022 Aug; Vol. 236, pp. 108052. Date of Electronic Publication: 2021 Dec 08.

Tumor-Mediated Neutrophil Polarization and Therapeutic Implications.

Autor: Raftopoulou S; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Valadez-Cosmes P; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Mihalic ZN; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Schicho R; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria., Kargl J; Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 16; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 16.