Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis

Autor: Datta, Harish K, Kringen, Marianne K, Tuck, Stephen P, Salpingidou, Georgia, Olstad, Ole K, Gautvik, Kaare M, Cockell, Simon J, Gautvik, Vigdis T, Prediger, Michael, Wu, Jun Jie, Birch, Mark A, Reppe, Sjur

Publikováno v: International journal of molecular sciences, 2022, Vol.23(6), pp.2957 [Peer Reviewed Journal]
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 2957

Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of the cerebellum 1 (ZIC1) is markedly increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9964391db26f33e0c6dee0673db9adac
http://dro.dur.ac.uk/36397/1/36397.pdf