Zobrazeno 1 - 10
of 101
pro vyhledávání: '"ZHIPENG YOU"'
Autor:
Jace Jones-Tabah, Kathy He, Nathan Karpilovsky, Konstantin Senkevich, Ghislaine Deyab, Isabella Pietrantonio, Thomas Goiran, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther del Cid Pellitero, Carol X.-Q. Chen, Wen Luo, Zhipeng You, Narges Abdian, Jamil Ahmad, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Stanley Fahn, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon Hassin-Baer, Roy N. Alcalay, Austen Milnerwood, Thomas M. Durcan, Ziv Gan-Or, Edward A. Fon
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Variants in the CTSB gene encoding the lysosomal hydrolase cathepsin B (catB) are associated with increased risk of Parkinson’s disease (PD). However, neither the specific CTSB variants driving these associations nor the functio
Externí odkaz:
https://doaj.org/article/e2786b44f0ab42b995b54fb1787459cd
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract To use Optical Coherence Tomography (OCT) to measure scleral thickness (ST) and subfoveal choroid thickness (SFCT) in patients with Branch Retinal Vein Occlusion (BRVO) and to conduct a correlation analysis. A cross-sectional study was condu
Externí odkaz:
https://doaj.org/article/9acafd2a3c1448828898c8930fc678bb
Autor:
Peter S. McPherson, Carl Laflamme, Kathleen Southern, Riham Ayoubi, Maryam Fotouhi, Walaa Alshalfie, Harvinder Virk, Zhipeng You, Carolyn Jones, Michael Biddle
Publikováno v:
F1000Research, Vol 12 (2024)
RNA-binding protein Fused-in Sarcoma (FUS) plays an essential role in various cellular processes. Mutations in the C-terminal domain region, where the nuclear localization signal (NLS) is located, causes the redistribution of FUS from the nucleus to
Externí odkaz:
https://doaj.org/article/64d8deecdefb4a53ac5fa2837cb1e422
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The study was intended to confirm whether Pars Plana Vitrectomy (PPV) with Internal Limiting Membrane (ILM) peeling and intravitreal injection mouse Nerve Growth Factor(mNGF) was effective for the treatment of Idiopathic Macular H
Externí odkaz:
https://doaj.org/article/740946442cd547448ef3951caf1b9cd7
Autor:
Zhipeng You, Peter S. McPherson, Carl Laflamme, Kathleen Southern, Riham Ayoubi, Walaa Alshafie
Publikováno v:
F1000Research, Vol 12 (2023)
Superoxide dismutase [Cu-Zn] 1 (SOD1), is an antioxidant enzyme encoded by the gene SOD1, responsible for regulating oxidative stress levels by sequestering free radicals. Identified as the first gene with mutations in Amyotrophic lateral sclerosis (
Externí odkaz:
https://doaj.org/article/17a3eb630f4b4903b846a476afd0743b
Autor:
Peter S. McPherson, Carl Laflamme, Kathleen Southern, Riham Ayoubi, Maryam Fotouhi, Walaa Alshalfie, Zhipeng You
Publikováno v:
F1000Research, Vol 12 (2023)
RNA-binding protein Fused-in Sarcoma (FUS) plays an essential role in various cellular processes. Mutations in the C-terminal domain region, where the nuclear localization signal (NLS) is located, causes the redistribution of FUS from the nucleus to
Externí odkaz:
https://doaj.org/article/04f26f0f204a462ab3f9959ffa5b98de
Autor:
Kangcheng Liu, Hua Zou, Huimin Fan, Hanying Hu, Yanhua Cheng, Jingying Liu, Xiaojian Wu, Bolin Chen, Zhipeng You
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Aldosterone, as a mineralocorticoid of adrenal origin, has effects that are not limited to the urinary tract. As an important regulator in Vasoactive hormone pathways, aldosterone may play an effect in the pathogenesis of diabetic retinopathy (DR) th
Externí odkaz:
https://doaj.org/article/2508b2a9fc414fc9b680a6b0b91cae67
Autor:
Cong Huang, Zhipeng You, Yijie He, Jiran Li, Yang Liu, Chunyan Peng, Zhixiong Liu, Xingan Liu, Jiahang Sun
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundTemporal lobe epilepsy (TLE) is a common chronic episodic illness of the nervous system. However, the precise mechanisms of dysfunction and diagnostic biomarkers in the acute phase of TLE are uncertain and hard to diagnose. Thus, we intende
Externí odkaz:
https://doaj.org/article/dc25f5f37db94ab9b0fda27685ad6078
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112134- (2023)
Summary: A hexanucleotide (GGGGCC)n repeat expansion in C9orf72 causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), eliciting toxic effects through generation of RNA foci, dipeptide repeat proteins, and/or loss of C9orf72 pr
Externí odkaz:
https://doaj.org/article/272697a70a5e473098b0781417cf2bdc
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
It is difficult to get evidence from randomized trials of a causal relationship between steroid hormones produced by the adrenal gland and gonad and retinal neurodegenerative disorders (RND). In this study, genetic variations of aldosterone (Aldo), a
Externí odkaz:
https://doaj.org/article/cec41311ad4f4fe2b5857e5aa94ff4be