Expert Consensus on the Diagnosis and Treatment of FGFR Gene-Altered Solid Tumors

Autor: Chunwei Xu, Bin Lian, Juanjuan Ou, Qian Wang, Wenxian Wang, Ke Wang, Dong Wang, Zhengbo Song, Aijun Liu, Jinpu Yu, Wenzhao Zhong, Zhijie Wang, Yongchang Zhang, Jingjing Liu, Shirong Zhang, Xiuyu Cai, Anwen Liu, Wen Li, Lili Mao, Ping Zhan, Hongbing Liu, Tangfeng Lv, Liyun Miao, Lingfeng Min, Yu Chen, Jingping Yuan, Feng Wang, Zhansheng Jiang, Gen Lin, Long Huang, Xingxiang Pu, Rongbo Lin, Weifeng Liu, Chuangzhou Rao, Dongqing Lv, Zongyang Yu, Xiaoyan Li, Chuanhao Tang, Chengzhi Zhou, Junping Zhang, Junli Xue, Hui Guo, Qian Chu, Rui Meng, Jingxun Wu, Rui Zhang, Jin Zhou, Zhengfei Zhu, Yongheng Li, Hong Qiu, Fan Xia, Yuanyuan Lu, Xiaofeng Chen, Rui Ge, Enyong Dai, Yu Han, Weiwei Pan, Fei Pang, Jintao Huang, Kai Wang, Fan Wu, Bingwei Xu, Liping Wang, Youcai Zhu, Li Lin, Yanru Xie, Xinqing Lin, Jing Cai, Ling Xu, Jisheng Li, Xiaodong Jiao, Kainan Li, Jia Wei, Huijing Feng, Lin Wang, Yingying Du, Wang Yao, Xuefei Shi, Xiaomin Niu, Dongmei Yuan, Yanwen Yao, Jianhui Huang, Yue Feng, Yinbin Zhang, Pingli Sun, Hong Wang, Mingxiang Ye, Zhaofeng Wang, Yue Hao, Zhen Wang, Bin Wan, Donglai Lv, Zhanqiang Zhai, Shengjie Yang, Jing Kang, Jiatao Zhang, Chao Zhang, Lin Shi, Yina Wang, Bihui Li, Zhang Zhang, Zhongwu Li, Zhefeng Liu, Nong Yang, Lin Wu, Huijuan Wang, Gu Jin, Guansong Wang, Jiandong Wang, Meiyu Fang, Yong Fang, Yuan Li, Xiaojia Wang, Jing Chen, Yiping Zhang, Xixu Zhu, Yi Shen, Shenglin Ma, Biyun Wang, Lu Si, Yuanzhi Lu, Ziming Li, Wenfeng Fang, Yong Song

Publikováno v: Global Medical Genetics, Vol 11, Iss 04, Pp 330-343 (2024)

The fibroblast growth factor receptor (FGFR) is a crucial receptor tyrosine kinase involved in essential biological processes, including growth, development, and tissue repair. However, FGFR gene mutations, including amplification, fusion, and mutati

Externí odkaz: https://doaj.org/article/d6d893b96da4470f8696347abc7c0079

Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical study

Autor: Zhijie Wang, Zixuan He, Rong Lin, Zhijie Feng, Xiuling Li, Xiangyu Sui, Lun Gu, Tian Xia, Dihan Zhou, Bali Zhao, Yanqing Li, Zhaoshen Li, Yu Bai

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)

Abstract Background A blood-based diagnostic test is a promising strategy for colorectal cancer (CRC). The MethyDT test (IColohunter), which detects methylation levels of NTMT1 and MAP3K14 -AS1, exhibited potential in discriminating CRC, but its clin

Externí odkaz: https://doaj.org/article/9221a2d2a8214fc6a2d58e94483008e0

Prediction performance comparison of biomarkers for response to immune checkpoint inhibitors in advanced non‐small cell lung cancer

Autor: Jie Zhao, Wei Zhuang, Boyang Sun, Hua Bai, Zhijie Wang, Jia Zhong, Rui Wan, Lihui Liu, Jianchun Duan, Jie Wang

Publikováno v: Thoracic Cancer, Vol 15, Iss 13, Pp 1050-1059 (2024)

Abstract Background The aim of the present study was to compare the predictive accuracy of PD‐L1 immunohistochemistry (IHC), tissue or blood tumor mutation burden (tTMB, bTMB), gene expression profile (GEP), driver gene mutation, and combined bioma

Externí odkaz: https://doaj.org/article/4d82365c7869466fbf311b8a9bb541db

Boron Neutron Capture Therapy‐Derived Extracellular Vesicles via DNA Accumulation Boost Antitumor Dendritic Cell Vaccine Efficacy

Autor: Linwen Lv, Junzhe Zhang, Yujiao Wang, Haojun Liang, Qiuyang Liu, Fan Hu, Hao Li, Wenxi Su, Junhui Zhang, Ranran Chen, Ziteng Chen, Zhijie Wang, Jiacheng Li, Ruyu Yan, Mingxin Yang, Ya‐nan Chang, Juan Li, Tianjiao Liang, Gengmei Xing, Kui Chen

Publikováno v: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

Abstract Radiated tumor cell‐derived extracellular vesicles (RT‐EVs) encapsulate abundant DNA fragments from irradiated tumor cells, in addition to acting as integrators of multiple tumor antigens. Accumulating evidence indicates these DNA fragme

Externí odkaz: https://doaj.org/article/f9357274b19e45459d5bb9e71baecaaa

Causal effects between personality and psychiatric traits and lung cancer: a bidirectional two-sample Mendelian randomization and bibliometric study

Autor: Siyuan Chen, Zhijuan Du, Yuhui Qin, Yanan Li, Yu Pan, Yu Qiao, Juan Chen, Zhengyang Hou, Shuai Jin, Haitao Tao, Heying Yu, Jiapei Qin, Mingzhen Zhu, Zhijie Wang, Zhefeng Liu

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

IntroductionThe causality between personality and psychiatric traits and lung cancer (LC) remains unclear. Therefore, we aimed to elucidate the causality between these traits and LC.MethodsBidirectional two-sample Mendelian randomization (MR) and bib

Externí odkaz: https://doaj.org/article/b28129a59ff249468a39865ed565279c