Zobrazeno 1 - 10
of 1 940
pro vyhledávání: '"ZHI Xiao"'
Autor:
Xiaoshuang Liu, Dongfang Gu, Yiru Zhang, Yingli Jiang, Zhi Xiao, Rongfang Xu, Ruiying Qin, Juan Li, Pengcheng Wei
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background High-efficiency prime editing (PE) is desirable for precise genome manipulation. The activity of mammalian PE systems can be largely improved by inhibiting DNA mismatch repair by coexpressing a dominant-negative variant of MLH1. H
Externí odkaz:
https://doaj.org/article/6b5a316d38b349c8a7375e4dd156cca6
Autor:
Quan Zheng, Shunqi Mei, Zhi Xiao, Jinyu Yang, Zhen Chen, Qiao Xu, Alexey Guryev, Burial Lygdenov
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 3807-3821 (2024)
The cooling method has a very important effect on the microstructure and properties of the boride layer. In this study, a rare earth-Cr composite boronizing method to prepare boride ceramic coatings on 4Cr5MoSiV1 alloy steel was used. The samples wer
Externí odkaz:
https://doaj.org/article/a0c9d0ce1e2046558d450f5d9b14ad16
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The prognostic value of SII (Systemic Immune-Inflammation Index) in HER-2-positive breast cancer (BC) patients, regardless of whether they receive trastuzumab treatment, and its potential value to distinguish patients who may benefit from tr
Externí odkaz:
https://doaj.org/article/e7fa1837b88e40508a5383c30ac7dd7d
Autor:
Nianhua Ding, Jian Pang, Xuan Liu, Xiongbin He, Wei Zhou, Haiqing Xie, Jianqi Feng, Guo Wang, Jie Tang, Jing Cao, Liying He, Yingjian He, Shouman Wang, Zhi Xiao
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Purpose This study aimed to evaluate the prognostic role of the baseline neutrophil/lymphocyte ratio (NLR) in HER2-positive metastatic breast cancer (MBC) patients treated with trastuzumab/pertuzumab. Experimental design Data from 780 patien
Externí odkaz:
https://doaj.org/article/3479d1ded519474488b5ce32f8c28ae9
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Body sizes and head anatomical characteristics play the major role in the head injuries sustained by vulnerable road users (VRU) in traffic accidents. In this study, in order to study the influence mechanism of body sizes and head anatomical characte
Externí odkaz:
https://doaj.org/article/6596f19f79ca4b2f93ce752a36699cfa
Autor:
Mengjie Chen, Jieying Peng, Guanghao Zhu, Cunhui Qian, Zhi Xiao, Xianmin Song, Haojun Yu, Rushi Huang, Wei Wang, Hongliang Zheng, Yafeng Yu
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308723 (2024)
Fibrosis is a complex pathological process that can lead to the permanent loss of biological function, with P2ry2 playing a crucial role in this process. Long non-coding RNAs (lncRNAs) have been reported to play an critically important role in the fi
Externí odkaz:
https://doaj.org/article/edc0e618679d42c2be1d02c751ca0504
Publikováno v:
Materials Research Express, Vol 11, Iss 11, p 115202 (2024)
In artificial freezing engineering, the freezing temperature is an important factor affecting soil frost heave deformation, and studying its impact is of great significance. The frost heave ratio of soil is a crucial factor for designing and predicti
Externí odkaz:
https://doaj.org/article/03e16b51179844d1959576f80e6f828a
Autor:
Juan Li, Yiyong Wei, Junli Zhou, Helin Zou, Lulin Ma, Chengxi Liu, Zhi Xiao, Xingfeng Liu, Xinran Tan, Tian Yu, Song Cao
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background The noradrenergic neurons of locus coeruleus (LC) project to the spinal dorsal horn (SDH), and release norepinephrine (NE) to inhibit pain transmission. However, its effect on pathological pain and the cellular mechanism in the SD
Externí odkaz:
https://doaj.org/article/c526d344789948029f8aadda0ec180b4
Autor:
Jiang He, Liyu Liu, Feiyu Tang, You Zhou, Huan Liu, Can Lu, Deyun Feng, Hong Zhu, Yitao Mao, Zhi Li, Lu Zhang, Yuemei Duan, Zhi Xiao, Musheng Zeng, Liang Weng, Lun-Quan Sun
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Epstein-Barr virus (EBV) and human papillomavirus (HPV) infection is the risk factors for nasopharyngeal carcinoma and cervical carcinoma, respectively. However, clinical analyses demonstrate that EBV or HPV is associated with improved respo
Externí odkaz:
https://doaj.org/article/37c8cc13b2fc461dbafdcb07de6276b4
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 10, Pp 1395-1403 (2021)
Objective(s): Clinically effective analgesia treatment for patients afflicted with osteocarcinoma lessens the intensity of pain. The midbrain periaqueductal gray (PAG) plays a critical role in pain modulation, and activation of P2X3 receptors in this
Externí odkaz:
https://doaj.org/article/12004276b0944afea4a5d56d909b05b6