Zobrazeno 1 - 10
of 77
pro vyhledávání: '"ZHENGHANG ZHAO"'
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1657 (2023)
Recent studies have shown that FMS-like receptor tyrosine kinase 3 (Flt3) has a beneficial effect on cardiac maladaptive remodeling. However, the role and mechanism of Flt3 in mitochondrial dynamic imbalance under cardiac stress remains poorly unders
Externí odkaz:
https://doaj.org/article/a8edf3eb5de6426daf7a510c1af1415e
Autor:
Xianglan Wei, Siyao Li, Tingting Li, Longzhu Liu, Yuan Liu, Hao Wang, Yong Zhou, Fanfan Liang, Xiaojiang Yu, Weijin Zang, Ming Zhao, Zhenghang Zhao
Publikováno v:
Journal of Functional Foods, Vol 65, Iss , Pp 103712- (2020)
Hepatic fibrosis is a chronic process characterized by excessive production of extracellular matrix in response to liver injury, which eventually leads to cirrhosis and even death. Growing evidence has demonstrated that pomegranate could efficiently
Externí odkaz:
https://doaj.org/article/20831e75333e42a1bed8029bafad5614
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background and Purpose: Store-operated calcium entry (SOCE) is an important physiological phenomenon that extensively mediates intracellular calcium ion (Ca2+) load. It has been previously found in myocytes isolated from neonatal or diseased hearts.
Externí odkaz:
https://doaj.org/article/5cf32a4dbba14f27afd9c212fdafef6c
Autor:
Lumin Wang, Xiangyun Meng, Zhiguang Yuchi, Zhenghang Zhao, Dehui Xu, David Fedida, Zhuren Wang, Chen Huang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 6, Pp 2250-2262 (2015)
Background: Brugada syndrome (BrS) is a genetically determined cardiac electrical disorder, characterized by typical electrocardiography (ECG) alterations, and it is an arrhythmogenic syndrome that may lead to sudden cardiac death. The most common ge
Externí odkaz:
https://doaj.org/article/d9da9229cbd44cdcad6f1f4d0ac3c718
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80574 (2013)
Recent studies have suggested that mitochondria may play important roles in the Ca(2+) homeostasis of cardiac myocytes. However, it is still unclear if mitochondrial Ca(2+) flux can regulate the generation of Ca(2+) waves (CaWs) and triggered activit
Externí odkaz:
https://doaj.org/article/2811fc0e503445b5a258f91a5f4ba970
Autor:
Sabine M. Neumayer, Zhenghang Zhao, Andrew O’Hara, Michael A. McGuire, Michael A. Susner, Sokrates T. Pantelides, Petro Maksymovych, Nina Balke
Publikováno v:
ACS Nano. 16:2452-2460
Autor:
Xixi Jiang, Kaina Zhang, Chenying Gao, Wenzhuo Ma, Mengqing Liu, Xinyu Guo, Gaowa Bao, Bing Han, Hao Hu, Zhenghang Zhao
Publikováno v:
The FASEB Journal. 36
FMS-like receptor tyrosine kinase 3 (Flt3) expression was reported to increase in the heart in response to pathological stress, but the role of Flt3 activation and its underlying mechanisms remain poorly elucidated. This study was designed to investi
Autor:
Hao Huang, Maolin Zhang, Kuo-Wei Huang, Dalaver H. Anjum, Jr-Hau He, Zedong Zhang, Dingsheng Wang, Zhenghang Zhao
Publikováno v:
ACS Catalysis. 11:11103-11108
This work was supported by King Abdullah University of Science and Technology. The authors thank the BL14W1 station for XAFS measurement in the Shanghai Synchrotron Radiation Facility (SSRF)
Publikováno v:
Toxicology. 481
Sorafenib (Sor), a novel multi-target anticancer drug also induces severe toxicity in heart, while the mechanism of its cardiotoxicity remains to be fully elucidated. Dysregulation of autophagy and mitochondrial dynamics imbalance have been implicate
Publikováno v:
Pflugers Arch
Hibernation allows animals to enter an energy conserving state to survive severe drops in external temperatures and a shortage of food. It has been observed that the heart of mammalian hibernators exhibits intrinsic protection against ischemia-reperf