Zobrazeno 1 - 10
of 21
pro vyhledávání: '"ZALDIVAR COMENGES JOSE'"'
Publikováno v:
In International Journal of Production Economics 2008 114(2):631-645
Autor:
Bessems, Jos G., Loizou, George, Krishnan, Kannan, Clewell, Harvey J., III, Bernasconi, Camilla, Bois, Frederic, Coecke, Sandra, Collnot, Eva-Maria, Diembeck, Walter, Farcal, Lucian Romeo, Geraets, Liesbeth, Gundert-Remy, Ursula, Kramer, Nynke, Küsters, Gabriele, Leite, Sofia B., Pelkonen, Olavi R., Schröder, Klaus, Testai, Emanuela, Wilk-Zasadna, Iwona, Zaldívar-Comenges, José-Manuel
Publikováno v:
In Regulatory Toxicology and Pharmacology February 2014 68(1):119-139
Publikováno v:
In Developments in Environmental Modelling 2012 25:51-71
Autor:
ZALDIVAR COMENGES Jose', MENNECOZZI MILENA, MACKO Peter, RODRIGUES Robim, BOUHIFD Mounir, BARAIBAR FENTANES Joaquin
There is a need to extrapolate from in vitro concentrations to in vivo dose. To do this extrapolation it is necessary to be able to calculate free concentrations in both systems and then compare them. Concerning the in vitro side, in the first part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::57fa1b01e65a69461ecba9b944e13f93
http://publications.jrc.ec.europa.eu/repository/handle/JRC63686
http://publications.jrc.ec.europa.eu/repository/handle/JRC63686
Autor:
ZALDIVAR COMENGES Jose', STROZZI F.
Many biological oscillators consist of a positive plus a negative feedback loop even though a negative feedback loop is enough to generate oscillations. In this work, we have analyzed from the point of view of the divergence of the system and, and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::c19cb88a3cfff519d00bd87c3a487cc1
http://publications.jrc.ec.europa.eu/repository/handle/JRC65766
http://publications.jrc.ec.europa.eu/repository/handle/JRC65766
In vitro neuronal networks are a simplified and accessible model of the central nervous system. Moreover, they exhibit morphological and physiological properties and activity-dependent path-specific synaptic modification similar to the in vivo tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::4345b560a0f4f499a9784e7f3a22a27d
http://publications.jrc.ec.europa.eu/repository/handle/JRC66327
http://publications.jrc.ec.europa.eu/repository/handle/JRC66327
Autor:
ZALDIVAR COMENGES Jose', STROZZI F.
Chemical toxicity in most of the cases has a metabolic component and metabolic pathways are the most studied biochemical reactions. For these reasons we have started to analyze modelling approaches for studying toxicity at molecular level using the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::fc51e9dea953355e7fb579d751d63da4
http://publications.jrc.ec.europa.eu/repository/handle/JRC61087
http://publications.jrc.ec.europa.eu/repository/handle/JRC61087
Autor:
DAGINNUS Klaus, GOTTARDO Stefania, MOSTRAG-SZLICHTYNG A., WILKINSON Helen, WHITEHOUSE Paul, PAYA PEREZ Ana, ZALDIVAR COMENGES Jose'
A model-based prioritization exercise that considers two aspects, i.e. the hazard of a certain chemical and its exposure levels, and focuses on aquatic ecosystems has been carried out for the Water Framework Directive (WFD) implementation. The exerci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::ed43fc84c73a3980a174d9e66d7b750f
http://publications.jrc.ec.europa.eu/repository/handle/JRC57344
http://publications.jrc.ec.europa.eu/repository/handle/JRC57344
There is a need to integrate existing in vitro dose-response data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would contribute towards the reduction of animal use in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::2137417cff0fc28608b4e5c325238d65
http://publications.jrc.ec.europa.eu/repository/handle/JRC58506
http://publications.jrc.ec.europa.eu/repository/handle/JRC58506
Autor:
ZALDIVAR COMENGES Jose'
With the implementation of the Water Framework Directive and the daughter directive on Environmental Quality Standards (EQS), the development of EQS values for biota has become an important issue. However, for certain hydrophobic compounds, bioaccumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1739::3d85e3ae0f5bb1891021f60e7d6af0b4
http://publications.jrc.ec.europa.eu/repository/handle/JRC54064
http://publications.jrc.ec.europa.eu/repository/handle/JRC54064