Zobrazeno 1 - 10
of 168
pro vyhledávání: '"ZACHARY FREYBERG"'
Autor:
BaDoi N. Phan, Madelyn H. Ray, Xiangning Xue, Chen Fu, Robert J. Fenster, Stephen J. Kohut, Jack Bergman, Suzanne N. Haber, Kenneth M. McCullough, Madeline K. Fish, Jill R. Glausier, Qiao Su, Allison E. Tipton, David A. Lewis, Zachary Freyberg, George C. Tseng, Shelley J. Russek, Yuriy Alekseyev, Kerry J. Ressler, Marianne L. Seney, Andreas R. Pfenning, Ryan W. Logan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal dysfunction is linked to psychiatric disorders, including opioid use disorder (OUD). Striatal subregions are divided based on neuroanato
Externí odkaz:
https://doaj.org/article/82f5489316cf4dc69335f0d491c9b09c
Autor:
Jiwon Lee, Xiangning Xue, Emily Au, William B. McIntyre, Roshanak Asgariroozbehani, Kristoffer Panganiban, George C. Tseng, Maria Papoulias, Emily Smith, Jonathan Monteiro, Divia Shah, Kateryna Maksyutynska, Samantha Cavalier, Emril Radoncic, Femin Prasad, Sri Mahavir Agarwal, Robert Mccullumsmith, Zachary Freyberg, Ryan W. Logan, Margaret K. Hahn
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Antipsychotic (AP)-naive first-episode psychosis (FEP) patients display early dysglycemia, including insulin resistance and prediabetes. Metabolic dysregulation may therefore be intrinsic to psychosis spectrum disorders (PSDs), independent o
Externí odkaz:
https://doaj.org/article/9a100fe7544345238becc07220eee009
Autor:
Ariel M. Lyons-Warren, Evelyne K. Tantry, Elizabeth H. Moss, Mikhail Y. Kochukov, Benjamin D.W. Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R. Arenkiel
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113471- (2023)
Summary: Co-transmission of multiple neurotransmitters from a single neuron increases the complexity of signaling information within defined neuronal circuits. Superficial short-axon cells in the olfactory bulb release both dopamine and γ-aminobutyr
Externí odkaz:
https://doaj.org/article/d426480f99f24a6a8a652cb6c1443abd
Autor:
Najibul Haque Sarker, Zaber Abdul Hakim, Ali Dabouei, Mostofa Rafid Uddin, Zachary Freyberg, Andy MacWilliams, Joshua Kangas, Min Xu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
In this work, we address the problem of detecting anomalies in a certain laboratory automation setting. At first, we collect video images of liquid transfer in automated laboratory experiments. We mimic the real-world challenges of developing an anom
Externí odkaz:
https://doaj.org/article/205aa24d6bc94c7f902cd8a172f72e1b
Autor:
Karis Kosar, Pamela Cornuet, Sucha Singh, Elizabeth Lee, Silvia Liu, Jenesis Gayden, Toshifumi Sato, Zachary Freyberg, Gavin Arteel, Kari Nejak‐Bowen
Publikováno v:
Hepatology Communications, Vol 5, Iss 12, Pp 2019-2034 (2021)
We previously identified an up‐regulation of specific Wnt proteins in the cholangiocyte compartment during cholestatic liver injury and found that mice lacking Wnt secretion from hepatocytes and cholangiocytes showed fewer proliferating cholangiocy
Externí odkaz:
https://doaj.org/article/c151200c32814023a236e26d6f6575c4
Autor:
Mackenzie C. Gamble, Benjamin R. Williams, Navsharan Singh, Luca Posa, Zachary Freyberg, Ryan W. Logan, Stephanie Puig
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Despite the prevalence of opioid misuse, opioids remain the frontline treatment regimen for severe pain. However, opioid safety is hampered by side-effects such as analgesic tolerance, reduced analgesia to neuropathic pain, physical dependence, or re
Externí odkaz:
https://doaj.org/article/585f4542de6e47da906dfef65e3d5feb
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/6e682d5df03a45348843ad23006f16d6
Autor:
Despoina Aslanoglou, Suzanne Bertera, Laura Friggeri, Marta Sánchez-Soto, Jeongkyung Lee, Xiangning Xue, Ryan W. Logan, J. Robert Lane, Vijay K. Yechoor, Peter J. McCormick, Jens Meiler, R. Benjamin Free, David R. Sibley, Rita Bottino, Zachary Freyberg
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104771- (2022)
Summary: Bromocriptine is approved as a diabetes therapy, yet its therapeutic mechanisms remain unclear. Though bromocriptine’s actions have been mainly attributed to the stimulation of brain dopamine D2 receptors (D2R), bromocriptine also targets
Externí odkaz:
https://doaj.org/article/073b353a30d149d4b39ba15b63d8a932
Autor:
Kelly Barko, Micah Shelton, Xiangning Xue, Yvette Afriyie-Agyemang, Stephanie Puig, Zachary Freyberg, George C. Tseng, Ryan W. Logan, Marianne L. Seney
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Microglia are resident macrophages of the brain, performing roles related to brain homeostasis, including modulation of synapses, trophic support, phagocytosis of apoptotic cells and debris, as well as brain protection and repair. Studies assessing m
Externí odkaz:
https://doaj.org/article/427602fb66db42469bb726d111f3fb39
Autor:
Tarun Gupta, Xuehai He, Mostofa Rafid Uddin, Xiangrui Zeng, Andrew Zhou, Jing Zhang, Zachary Freyberg, Min Xu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Macromolecular structure classification from cryo-electron tomography (cryo-ET) data is important for understanding macro-molecular dynamics. It has a wide range of applications and is essential in enhancing our knowledge of the sub-cellular environm
Externí odkaz:
https://doaj.org/article/e68ba90dbdbe4c4d915a8d55cd97f284