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Autor:
Z. Wiesenfeld-Hallin, Jing-Xia Hao, X.-J. Xu, John Shine, Tiina P. Iismaa, Jacqueline N. Crawley, Arie S. Jacoby, Karin Hygge Blakeman
Publikováno v:
Neuroscience. 117:221-227
The neuropeptide galanin may have a role in modulation of nociception, particularly after peripheral nerve injury. The effect of galanin is mediated by at least three subtypes of receptors. In the present study, we assessed the nociceptive sensitivit
Publikováno v:
Experimental Brain Research. 139:354-358
The release of the neuropeptide galanin was measured with microdialysis in the dorsal horn of the rat spinal cord. Recovery of unlabeled galanin-like immunoreactivity (GAL-LI) in vitro was measured with radioimmunoassay (RIA) and was found to be 1.4-
Publikováno v:
Neuroscience. 95:197-207
In order to further investigate the interaction between the octapeptide cholecystokinin and opioid analgesia in the spinal cord we used double-colour immunofluorescence to examine the anatomical distribution of cholecystokinin and μ-opioid receptors
Publikováno v:
Acta Anaesthesiologica Scandinavica. 43:1027-1034
Background: Increased response to mechanical or cold stimulation of hind paws was observed in rats with partial sciatic nerve injury as a result of photochemically induced ischemia. The present study examined the effects of intrathecal morphine, clon
Publikováno v:
Neuropeptides. 32:73-78
The effects of intrathecal (i.t) administration of cholecystokinin (CCK) on the hindlimb flexor withdrawal reflex were compared in decerebrate, spinalized, unanaesthetized rats with intact sciatic nerves or 14–26 days after unilateral transection o
Publikováno v:
Neuropeptides. 31:287-291
The effects of RB 101 {N-[(R,S)-2-benzyl-3[(S)(2-amino-4-methylthio)butyl dithio]-1-oxo-propyl]-L-phenylalanine benzyl ester}, a complete inhibitor of enkephalin-degrading enzymes and CI 988, a selective antagonist of the cholecystokinin (CCK)-B rece
Publikováno v:
Neuropeptides. 30:203-206
The interaction between morphine and L740,093, a newly developed highly potent antagonist of cholecystokinin-B receptors, was examined in electrophysiological and behavioural studies. Intravenous L740, 093 at 0.01 mg/kg had no effect on its own, but
Publikováno v:
Brain Research. 707:180-188
The effect of axotomy (3, 10 and 21 days) on the expression of some neuronal markers was analysed in dorsal root ganglia and spinal cord of guinea-pigs using immunohistochemistry. Three weeks following injury, substance P-like immunoreactivity (-LI)
Publikováno v:
Neuroscience. 68:1219-1227
The effect of moderate and high intrathecal doses of clonidine, an α2 adrenoceptor agonist, or a high dose of morphine on sciatic nerve section-induced expression of c-Fos-like immunoreactivity was studied in laminae I and II of the dorsal horn and