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Publikováno v:
Journal of Acquired Immune Deficiency Syndromes. 27:389-397
This study addressed the role of T-cell immune activation in determining HIV-1 plasma viral load and CD4+ T-cell blood levels during HIV-1 infection. A decrease of blood CD4 levels and CD4/CD8 ratios and an increase of CD8 levels in both treated (n =
Autor:
Alexander Kalinkovich, Qibin Leng, Z. Weisman, Gadi Borkow, Dawit Wolday, Miguel Stein, Zvi Bentwich
Publikováno v:
Scandinavian Journal of Infectious Diseases. 33:568-571
Helminth infections affect over a quarter of the world's population, especially in the developing countries. These long-lasting parasitic infections cause widespread immune activation and dysregulation, a dominant Th2 cytokine immune profile and an i
Publikováno v:
Journal of Clinical Investigation. 106:1053-1060
Helminthic parasites cause widespread, persistent infections in humans. The immigration of Ethiopians to Israel (a group denoted here by “Eth.”), many of them infested with helminths and in a chronic immune-activation state, enabled us to investi
Publikováno v:
Clinical and Experimental Immunology. 114:414-421
SUMMARYWe have previously reported the presence of marked immune dysregulation with a dominant Th2 profile, in a population of Ethiopian immigrants (ETH) in Israel heavily infected with helminths. In order to characterize better this immune dysregula
Publikováno v:
Scandinavian Journal of Immunology. 43:556-565
NCC recognize a conserved target cell antigen (NKTag) expressed on protozoan parasites and on transformed tumour cells. In the present study, synthetic peptides corresponding to N-terminal, C-terminal and internal NKTag(deduced) amino acid sequences
Publikováno v:
Clinical and Experimental Immunology. 103:239-243
SUMMARY The infectious disease background and particularly the helminth infections that are endemic in Africa could have profound effects on the host immune system. Studies that we have performed on an Ethiopian HIV− immigrant population that has r
Publikováno v:
Immunology Today. 16:187-191
The AIDS epidemic in Africa is very different from the epidemic in the West. As suggested here by Zvi Bentwich, Alexander Kalinkovich and Ziva Weisman, this appears to be primarily a consequence of the over-activation of the immune system in the Afri
Publikováno v:
Clinical Experimental Allergy. 20:389-393
In the present study we assessed the effect of leukotriene C4 on ciliary beat frequency in vitro. Chicken tracheas were sliced into thin rings and ciliary activity was viewed microscopically. Ciliary beat frequency was measured through an optical fib
Autor:
A, Kalinkovich, Z, Weisman, Q, Leng, G, Borkow, M, Stein, Z, Greenberg, S, Zlotnikov, S, Eitan, Z, Bentwich
Publikováno v:
Journal of human virology. 2(5)
This study was undertaken to determine the contribution of HIV co-receptors and beta chemokine secretion to the increased susceptibility for human immunodeficiency virus (HIV) infection of peripheral blood mononuclear cells (PBMC) obtained from HIV-s