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Autor:
Z Spolarics
Publikováno v:
Hepatology. 24:691-696
Autor:
Charles H. Lang, M. E. Gelato, Wansong Pan, Jie Fan, A. J. Kolasa, C. S. Patlak, Z. Spolarics, D. Char, S. R. Maitra
Publikováno v:
Scopus-Elsevier
Lipopolysaccharide (LPS) produces a rapid and sustained reduction in the circulating concentration of insulin-like growth factor I (IGF-I), which may be responsible, in part, for the alterations in protein metabolism observed in these animals. The pu
Autor:
Z Spolarics
Publikováno v:
Hepatology. 13:277-281
Publikováno v:
Journal of leukocyte biology. 70(2)
The presence of dysfunctional/damaged red blood cells (RBCs) has been associated with adverse clinical effects during the inflammatory response. The aim of this study was to elucidate whether oxidatively modified, autologous RBCs modulate monocyte cy
Publikováno v:
American journal of hematology. 63(3)
Autor:
Z. Spolarics
Publikováno v:
The American journal of physiology. 270(4 Pt 1)
Reactive oxygen species (ROS) are mediators of cellular injury and play a putative role in the onset of hepatic damage during endotoxemia or sepsis. It has been suggested that induction of glucose-6-phosphate (G-6-P) dehydrogenase, the key enzyme of
Publikováno v:
Hepatology (Baltimore, Md.). 17(5)
Neutrophils and macrophages play an important role in the body's microbicidal defense and have been implicated in the induction of tissue injury in reperfusion, endotoxemia and septic shock. Cellular host defense is accompanied by enhanced glucose us
Publikováno v:
Hepatology (Baltimore, Md.). 17(5)
The role of neutrophil CD11b/CD18 (Mac-1) adhesion proteins in the pathogenesis of hepatic reperfusion injury was investigated in an experimental model. Male Fischer rats were treated with a CD11b monoclonal antibody or an isotype-matched IgM control
Publikováno v:
The American journal of physiology. 264(4 Pt 1)
The hypothesis that complement factors may be involved in the postischemic activation of Kupffer cells (KC) and polymorphonuclear neutrophils (PMN) was investigated in a model of hepatic ischemia (45 min) and reperfusion in male Fischer rats in vivo.