Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Z. Sheng Guo"'
Autor:
Zuqiang Liu, Yan Ge, Haiyan Wang, Congrong Ma, Mathilde Feist, Songguang Ju, Z. Sheng Guo, David L. Bartlett
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
IL-2 is used systemically for cancer therapy but it is associated with severe toxicity. Here, the authors design a recombinant vaccinia virus expressing membrane-bound IL-2 that shows therapeutic efficacy alone or in combination with checkpoint inhib
Externí odkaz:
https://doaj.org/article/bf8c62b2e7b9492694731295e94b4d6e
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Anti-PD-L1 therapy often fails in cancers with minimal lymphocytic infiltrates and low PD-L1 expression. Here, the authors show that an oncolytic virus increases PD-L1 expression in cancer models and that the combination with an anti-PD-L1 antibody e
Externí odkaz:
https://doaj.org/article/08d52995317b46989e958cc19d18bdfc
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 192K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3fef22da95b84c57bcb8fc06439680
https://doi.org/10.1158/0008-5472.22394370
https://doi.org/10.1158/0008-5472.22394370
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
Oncolytic virotherapy using vaccinia virus (Vv) has shown some encouraging antitumor responses in mouse models and patients, but the breadth of efficacy in clinical trials has been somewhat limited. Given that antitumor effects have correlated with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24ed971887f3363375d20f897255dd7
https://doi.org/10.1158/0008-5472.c.6504012.v1
https://doi.org/10.1158/0008-5472.c.6504012.v1
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 322K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451c8ae4ef7563d27881149ae3e9f261
https://doi.org/10.1158/0008-5472.22394373.v1
https://doi.org/10.1158/0008-5472.22394373.v1
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 94K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc99e1da177319cdc731fd3454ba104d
https://doi.org/10.1158/0008-5472.22394358
https://doi.org/10.1158/0008-5472.22394358
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120ba74b6f75df9877256b3e9bbce6f1
https://doi.org/10.1158/0008-5472.22394364
https://doi.org/10.1158/0008-5472.22394364
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 110K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365fe039ef1c0c6d7cff8da865e7a0cc
https://doi.org/10.1158/0008-5472.22394361
https://doi.org/10.1158/0008-5472.22394361
Autor:
Phillip K. Darcy, Michael H. Kershaw, Mark J. Smyth, David L. Bartlett, Z. Sheng Guo, Jenny A. Westwood, Trina J. Stewart, Connie P. Duong, Christel Devaud, Alison C. West, Jacqueline K. Flynn, Linda J. Howland, Liza B. John
PDF file - 182K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73081a85bc8cb9e12e6673316c8ca6da
https://doi.org/10.1158/0008-5472.22394367
https://doi.org/10.1158/0008-5472.22394367
Autor:
Yan Ge, Jinghua Ren, Weilin Liu, Hongqi Chen, Congrong Ma, David L. Bartlett, Junjie Ye, Enyong Dai, Haiyan Wang, Zuqiang Liu, Lingjuan Chen, Songguang Ju, Z. Sheng Guo
Publikováno v:
Theranostics
Background: Newly emerging cancer immunotherapy has led to significant progress in cancer treatment; however, its efficacy is limited in solid tumors since the majority of them are “cold” tumors. Oncolytic viruses, especially when properly armed,