Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Z. Peter Wang"'
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Alzheimer’s disease (AD) is a chronic progressive degenerative disease of the nervous system. Its pathogenesis is complex and is related to the abnormal expression of the amyloid β (Aβ), APP, and Tau proteins. Evidence has demonstrated t
Externí odkaz:
https://doaj.org/article/03ffefa1947844c387a1cfab8400f731
The Emerging Role of Sperm-Associated Antigen 6 Gene in the Microtubule Function of Cells and Cancer
Autor:
Da-Fang Zheng, Qi Wang, Jing-Ping Wang, Zheng-Qi Bao, Shi-Wu Wu, Li Ma, Da-Min Chai, Z. Peter Wang, Yi-Sheng Tao
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss , Pp 101-107 (2019)
Accumulated evidence shows that sperm-associated antigen 6 (SPAG6) gene has multiple biological functions. It maintains the normal function of a variety of cells including ciliary/flagellar biogenesis and polarization, neurogenesis, and neuronal migr
Externí odkaz:
https://doaj.org/article/e1c1aaf25652484b927fe44ab7090954
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 583-592 (2019)
Emerging evidence has demonstrated that miR-223 is critically involved in the progression of pancreatic cancer (PC); however, the underlying mechanisms are not fully elucidated. In the present study, we explored the molecular basis of miR-223-mediate
Externí odkaz:
https://doaj.org/article/732a21edd1e44a98a8a50f55620d7469
Autor:
Da-Min Chai, Yan-Zi Qin, Shi-Wu Wu, Li Ma, Yuan-Yuan Tan, Xiang Yong, Xiao-Li Wang, Z. Peter Wang, Yi-Sheng Tao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Backgrounds Emerging evidence has demonstrated that WISP2 is critically involved in cell proliferation, migration, invasion and metastasis in cancers. However, the function of WISP2 in esophageal squamous cell carcinoma (ESCC) is largely unc
Externí odkaz:
https://doaj.org/article/4c619a14244b48a2af504f573f0d74d4
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Accumulated evidence has demonstrated that WNT1 inducible signaling pathway protein (WISP) genes, which belong to members of the CCN growth factor family, play a pivotal role in tumorigenesis and progression of a broad spectrum of human canc
Externí odkaz:
https://doaj.org/article/6c1d38e88b2e401ea589322f6a5ac70e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 241-250 (2019)
Cervical cancer is one of the common malignancies in women worldwide. Exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal for development of effective treatment for this disease. Recently, systems biology approaches base
Externí odkaz:
https://doaj.org/article/36063bc775f44f4f8d6abda06587cd51
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 121-132 (2018)
Extensive research has suggested that miR-7 plays a critical role in cancer progression. However, the biological function of miR-7 in pancreatic cancer (PC) progression is poorly understood. Therefore, in the present study, we investigated the functi
Externí odkaz:
https://doaj.org/article/3731ec000cec4186901216147dfc7c69
Publikováno v:
Seminars in Cancer Biology. 85:219-233
Mounting evidence has demonstrated that a myriad of developmental signaling pathways, such as the Wnt, Notch, Hedgehog and Hippo, are frequently deregulated and play a critical role in regulating cancer stem cell (CSC) activity in human cancers, incl
Publikováno v:
Seminars in Cancer Biology. 67:171-179
Chemotherapeutic strategy has been widely used for treating malignance by targeting irregular expressed or mutant proteins with small molecular inhibitors (SMIs) or monoclonal antibodies (mAbs). However, most intracellular proteins lack of active sit
Publikováno v:
Journal of Cancer
Nitidine chloride (NC), a quaternary ammonium alkaloid, exhibits multiple biological activities, including antimalarial, antifungal, and antiangiogenesis. Recently, NC has been characterized to perform antitumor activity in a variety of malignancies.