Výsledky vyhledávání - "Z. O. Kubinski"

Practical and theoretical aspects of the DCB assay for carcinogenic and other genotoxic agents

Autor: H. Kubinski, Z. O. Kubinski

Publikováno v: Toxicity Assessment. 1:387-406

The DNA-cell binding (DCB) assay grew from our early studies demonstrating that in the presence of carcinogenic chemicals, radioactively labeled nucleic acids attached strongly to isolated cellular membranes and to intact prokaryotic and eucaryotic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0a0d8a62bbdb8c0ed5fece20ab9159b
https://doi.org/10.1002/tox.2540010402

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Increased cotransformation of distant markers and altered patterns of DNA-cell interactions following the exposure of transforming DNA to two carcinogenic and mutagenic alkylating agents, diethyl and dimethyl sulfate

Autor: Z. O. Kubinski, H. Kubinski

Publikováno v: Biochemical genetics. 20(11-12)

Transforming DNA exposed to either diethyl sulfate (diES) or dimethyl sulfate (diMS) is inactivated. The rate of inactivation depends on the marker tested and on the chemical used: diMS is more active than diES. Cotransformation of linked markers is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e5c258c60fb6070bc7005f1acc53a7
https://pubmed.ncbi.nlm.nih.gov/6819858

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Proximity of polyriboguanylic acid-reactive sites in mammalian DNA to portions of DNA preferentially hybridizing with cellular RNA

Autor: P K, Bhattacharya, H, Kubinski, Z O, Kubinski

Publikováno v: Acta biochimica Polonica. 31(1)

Transcribed portions of mouse nuclear DNA are adjacent to sites reacting preferentially with polyriboguanylic acid [poly(G)]. This spatial relationship was suggested by hybridization of radioactively labeled Ehrlich ascites RNA with denatured mouse D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37b275b5465d29db1553b0c3edc29cb2
https://pubmed.ncbi.nlm.nih.gov/6720193

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Alterations in Bacillus subtilis transforming DNA induced by beta-propiolactone and 1,3-propane sultone, two mutagenic and carcinogenic alkylating agents

Autor: H Kubinski, Z O Kubinski

Transforming DNA was exposed to either beta-propiolactone or 1,3-propane sultone and then used for transformation of competent bacteria to nutritional independence from tyrosine and tryptophan (linked markers) and leucine (an unlinked marker). The ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bebe698fb326cc8131de94a20b5fb8
https://europepmc.org/articles/PMC218518/

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Macromolecular complexes produced by chemical carcinogens and ultraviolet radiation

Autor: N R, Morin, P E, Zeldin, Z O, Kubinski, P K, Bhattacharya, H, Kubinski

Publikováno v: Cancer research. 37(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d82e5256a3b79cb4c676981f5c044f5
https://pubmed.ncbi.nlm.nih.gov/332339

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