Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Z. N. Nikiforova"'
Autor:
V. E. Shevchenko, Z. N. Nikiforova, T. I. Kushnir, I. A. Kudryavtsev, A. A. Mitrofanov, A. Kh. Bekyashev, N. E. Arnotskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 3, Pp 60-68 (2022)
Introduction. Treatment of glioblastoma multiforme remains little effective due to the rapidly developing recurrence of the tumor, due to its high tumorigenic potential, resistance to chemoradiation therapy and increased dissemination of glioma stem
Externí odkaz:
https://doaj.org/article/4ed35bbddfe14f3d9a46750dd338e922
Autor:
V. E. Shevchenko, A. S. Bryukhovetskiy, M. V. Filatov, V. S. Burdakov, Z. N. Nikiforova, I. S. Bryukhovetskiy, Yu. D. Vasilets, T. I. Kushnir, N. E. Arnotskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 5, Iss 1, Pp 60-69 (2018)
Background. Multiple myeloma (MM) is a hematologic malignancy of plasma cells. The microenvironment plays a key role in MM cell survival and drug resistance through release of soluble factors, expression of adhesion molecules and release of exosomes
Externí odkaz:
https://doaj.org/article/ab53387211b74acbb314daf245e97323
Autor:
V. E. Shevchenko, I. S. Bryukhovetskiy, Z. N. Nikiforova, S. V. Kovalev, I. A. Kudryavtsev, N. E. Arnotskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 3, Pp 67-74 (2017)
Background. The transforming growth factor beta 1 (TGF-β1) is one of the most important tissue factors secreted by the development of epithelial tumors. Increased expression of TGF-β1 in lung tumors promotes cancer cells survival enhancing their gr
Externí odkaz:
https://doaj.org/article/6f3b40dc61e849f7bcb302a3e8ac2ee8
Autor:
V. E. Shevchenko, S. V. Kovalev, N. E. Arnotskaya, Z. N. Nikiforova, I. A. Kudryavtsev, E. A. Savchenko, I. S. Bryukhovetskiy
Publikováno v:
Успехи молекулярной онкологии, Vol 3, Iss 2, Pp 50-59 (2016)
Background. Increased expression of transforming growth factor beta-1 (TGF-β1) in malignant brain tumors promotes cancer cells survival enhancing their growth, migration, invasion, angiogenesis, immune system suppression.Objective is to study molecu
Externí odkaz:
https://doaj.org/article/a08540554faf42d081d5e4f04cf5c892
Autor:
Z. N. Nikiforova, I. A. Kudryavtsev, N. E. Arnotskaya, I. S. Bryukhovetskiy, V. E. Shevchenko
Publikováno v:
Успехи молекулярной онкологии, Vol 3, Iss 2, Pp 26-33 (2016)
Glioblastoma multiforme, a World Health Organization grade IV malignant glioma, is the most common and lethal primary brain tumor with the median survival of approximately 15–25 months after treatment. Glioblastoma multiforme has been shown to be r
Externí odkaz:
https://doaj.org/article/f0a3b2b07c7440ba8132662675ad82c5
Publikováno v:
Опухоли женской репродуктивной системы, Vol 11, Iss 2, Pp 8-18 (2015)
Breast malignancies hold the lead in the pattern of cancers among women worldwide. Currently used methods for the instrumental diagnosis of breast cancer (BC) and their related diagnostic procedures are not sophisticated. The common constraint of ins
Externí odkaz:
https://doaj.org/article/7b17eeed209648babf3fdc6baf262981
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 1, Pp 8-14 (2014)
The expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential. The role of these factors in the regulation of the metastatic potential o
Externí odkaz:
https://doaj.org/article/7b9639f9facc474699651d72d2cd6ab9
Autor:
V. E. Shevchenko, M. A. Taipov, S. V. Kovalev, N. E. Arnotskaya, O. M. Pavlova, I. A. Kudryavtsev, Z. N. Nikiforova
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 19-28 (2014)
The proteome of lysates of the breast tumor cell lines MCF-7, BT-474, and ZR-75-1 was mapped, resulting in the sequence of 340 proteins. The proteins associated with the biosynthesis of PGE2 and with the regulation of cyclooxygenase-2 expression were
Externí odkaz:
https://doaj.org/article/2c37c8b863e74eb88f93c0677d76d243
Autor:
V. E. Shevchenko, M. A. Taipov, S. V. Kovalev, N. E. Arnotskaya, O. M. Pavlova, I. A. Kudryavtsev, Z. N. Nikiforova
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 2, Pp 4-10 (2014)
Mass spectrometric mapping of proteomic lysate of a MCF-7 cancer cell line was carried out, which identified 153 proteins having molecular weights of 5000 to 630000 Da, a high proportion of which was cytoplasmic and nuclear proteins. The latter accou
Externí odkaz:
https://doaj.org/article/2843f70f632b4c52b0ac271e7ea0f673
Autor:
M. A. Taipov, Z. N. Nikiforova, O. M. Pavlova, I. A. Kudryavtsev, N. Ye. Arnotskaya, V. Ye. Shevchenko
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 2, Pp 16-22 (2014)
This paper analyzes 15-PGDH gene expression in the human breast cancer (BC) cell liness and describes the molecular principles through which the expression of the enzyme 15-PGDH is controlled in the tumor cells with a varying metastatic potential. Th
Externí odkaz:
https://doaj.org/article/49f49b51047549a08734e93a9df53120