Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Z. Kállay"'
Publikováno v:
Radiation and Environmental Biophysics. 30:277-287
The heads of rats were irradiated by 4 MeV electrons in doses 90, 180, and 360 Gy. The observed times of deaths ranged 120-600, 60-420, and 150-370 min after 90, 180, and 360 Gy, respectively. A dose dependent decrease of the brain uptake index of ha
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 9:247-250
An analytical method to study the bioavailability of newly developed pentoxifylline sustained-release tablets has been developed and assessed in experiments on dogs. For the isolation of pentoxifylline and its metabolites from serum solid—liquid ex
Publikováno v:
Biopharmaceutics & Drug Disposition. 12:29-35
A high-performance liquid chromatographic method was developed to determine stobadin pharmacokinetics in dog and man. The relative bioavailability of stobadin dipalmitate compared with dihydrochloride was 46.4 per cent in dog. In man peak serum conce
Autor:
D. Mihalová, Mária Ďurišová, Z. Kállay, Katarína Bauerová, P. Bohov, Štefan Bezek, Tomas Trnovec, V. Faberová, V. Koprda, V. Ščasnár, M. Kukan, L. Šortés
Publikováno v:
Life Sciences. 65:2003-2005
The aim of this paper is to provide a brief overview of most important results of stobadine kinetic studies in rats, dogs, and human volunteers. In these studies, stobadine dihydrochloride and stobadine dipalmitate was used for intravenous and oral a
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:1121-1125
A high-performance gel permeation chromatographic separation method was developed for the isolation and characterisation of high molecular weight [3H]hyaluronic acid. The molecular characteristics of the labelled sample were MW=3.92x105 Da, MW/Mn=1.5
Publikováno v:
Experientia. 46:1017-1020
The passage of 6 model drugs; acetylsalicylic acid, chloramphenicol, ethimizol, carbisocaine, heptacaine, and diazepam, through the blood-brain barrier, was determined in unirradiated control rats and in animals 1, 3, and 7 days after irradiation of
Publikováno v:
Chromatographia. 30:201-204
High-molecular-weight sodium hyaluronate isolated from rooster combs was degraded by ultrasonication. The molecular weight of hyaluronate and its polydispersity was determined by gel-permeation chromatography. During 75-min treatment the molecular we
Publikováno v:
Journal of Antimicrobial Chemotherapy. 25:127-132
Guinea pigs were infected by intranasal administration of Klebsiella pneumoniae on day 7 after irradiation with a dose of 4 Gy and treated on days 8-10 by gentamicin 4 mg/kg bd im or by inhalation leading to estimated systemically absorbed doses of 5
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 525:459-463
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 22(2)