Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Z. Jane Li"'
Autor:
Kathleen S. Zandi, William Kissel, Brian M. Andresen, Chiu Charles K, John Charles Kath, David C. Whritenour, Matthew Frank Brown, Tung Le, Z. Jane Li, Eric Dias, Richard A. Buzon, Michel Couturier, Bryan Li, John L. Tucker, V. John Jasys, Joanna Teresa Negri, Poss Christopher Stanley, Frank J. Urban
Publikováno v:
Organic Process Research & Development. 9:466-471
Process development for the synthesis of 2-quinoxalinecarboxamide, N-[(1S,2S,4R)-4-(aminocarbonyl)-1-[(3-fluorophenyl)methyl]-2,7-dihydroxy-7-methyloctyl] is described. An optimized and streamlined process starting from lactone 2 was developed: Lacto
Publikováno v:
Journal of Pharmaceutical Sciences. 90:1523-1539
The lattice energies of a number of chiral drugs with known crystal structures were calculated using Dreiding II force field. The lattice energies, including van der Waals, Coulombic, and hydrogen-bonding energies, of homochiral and racemic crystals
Autor:
Z. Jane Li, David J.W. Grant
Publikováno v:
International Journal of Pharmaceutics. 137:21-31
A small enantiomeric excess in the crystallization medium during the crystal growth of the racemic compound, (±)-ephedrinium 2-naphthalenesulfonate, (±)-EN, is found to become partially incorporated into the racemic crystals. The small enantiomeric
Publikováno v:
Drug development and industrial pharmacy. 36(12)
Objective: The objective of this study was to investigate the effects of sodium lauryl sulfate (SLS) from different sources on solubilization/wetting, granulation process, and tablet dissolution of BILR 355 and the potential causes. Methods: The part
Autor:
and Ales Medek, Jon Bordner, Jason Albert Leonard, Andrew V. Trask, Z. Jane Li, Yuriy A. Abramov
Publikováno v:
Journal of the American Chemical Society. 128(25)
A cancer candidate, compound 1, is a weak base with two heterocyclic basic nitrogens and five hydrogen-bonding functional groups, and is sparingly soluble in water rendering it unsuitable for pharmaceutical development. The crystalline acid-base pair
Publikováno v:
Journal of pharmaceutical sciences. 88(3)
The identification of the racemic species, as a racemic compound, a racemic conglomerate, or a racemic solid solution (pseudoracemate), is crucial for rationalizing the potential for resolution of racemates by crystallization. The melting points and
Autor:
David J.W. Grant, Z. Jane Li
Publikováno v:
Journal of pharmaceutical sciences. 86(10)
Publikováno v:
CrystEngComm. 12:4231
In order to examine the balance between co-crystallization and proton transfer in a set of acid–base reactions, molecular electrostatic potential (MEP) surface calculations for substituted pyridines were correlated with their ability to communicate
Publikováno v:
CrystEngComm; Dec2010, Vol. 12 Issue 12, p4231-4239, 9p
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