Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Z. Ireland"'
Autor:
S. M. Sullivan, Paul B. Colditz, S. Tracey Bjorkman, Stephanie M. Miller, Kirat K. Chand, Z. Ireland
Publikováno v:
Journal of Neurochemistry. 139:471-484
Seizures are a common manifestation of hypoxic-ischaemic brain injury in the neonate. In status epilepticus models alterations to GABAAR subunit expression have been suggested to contribute to 1) abnormal development of the GABAergic system, 2) why s
Autor:
E. Pereleshina, Stacey J. Ellery, Peter Temple-Smith, Hayley Dickinson, David Walker, Domenic A. LaRosa, Rodney J. Snow, Z. Ireland
Publikováno v:
Pediatric Research. 74:479-483
Autor:
Rodney J. Snow, Z. Ireland, David W. Walker, Domenic A. LaRosa, Stacey J. Ellery, Bree Aimee O'Connell, Hayley Dickinson
Publikováno v:
Reproductive Sciences. 20:1096-1102
We have previously reported that maternal creatine supplementation protects the neonate from hypoxic injury. Here, we investigated whether maternal creatine supplementation altered expression of the creatine synthesis enzymes (arginine:glycine amidin
Autor:
Helena C. Parkington, Harold A. Coleman, Bobbi Fleiss, David W. Walker, Margie Castillo-Melendez, Z. Ireland
Publikováno v:
International Journal of Developmental Neuroscience. 29:757-766
Studies of human neonates, and in animal experiments, suggest that birth asphyxia results in functional compromise of the hippocampus, even when structural damage is not observable or resolves in early postnatal life. The aim of this study was to det
Publikováno v:
Developmental Neuroscience. 33:99-109
The principal function of the γ-aminobutyric acid (GABA) system in the adult brain is inhibition; however, in the neonatal brain, GABA provides much of the excitatory drive. As the brain develops, transmembrane chloride gradients change and the inhi
Publikováno v:
Neonatology. 97:45-51
We have previously developed a model of near-term intra-uterine hypoxia producing significant neonatal mortality (37%) in a small laboratory animal – the spiny mouse – which has precocial offspring at birth. The aim of the present study was to de
Publikováno v:
Developmental Neuroscience. 31:437-451
Birth asphyxia is associated with disturbed development of the neonatal brain. In this study, we determined if low-dose melatonin (0.1 mg/kg/day), administered to the mother over 7 days at the end of pregnancy, could protect against the effects of bi
Autor:
Margie Castillo-Melendez, Lisa Cathleen Hutton, Hayley Dickinson, David Walker, A. Shields, Z. Ireland
Publikováno v:
Journal of Paediatrics and Child Health. 43:A12-A77
Background: In 2005, the RCOG’s “Why Mothers Die” report showed that substandard care was a factor in nearly 70% of maternal deaths from direct causes, and nearly 40% of maternal deaths from indirect causes1. The failure of communication betwee
Autor:
Kit C.B. Roes, Willem M. van der Wal, Paul B. Colditz, Cacha Peeters-Scholte, S. Tracey Bjorkman, Z. Ireland, Xiyong Fan
Publikováno v:
Stroke. 44:809-811
Background and Purpose— To determine the optimal dose of 2-iminobiotin (2-IB) for the treatment of moderate to severe asphyxia in a neonatal piglet model of hypoxia-ischemia. Methods— Newborn piglets were subjected to a 30-minute hypoxia-ischemia
Autor:
Rodney J. Snow, David W. Walker, Hayley Dickinson, Z. Ireland, Michelle M Kett, Stacey J. Ellery
Publikováno v:
Pediatric research. 73(2)
Acute kidney injury (AKI) is a major complication for infants following an asphyxic insult at birth. We aimed to determine if kidney structure and function were affected in an animal model of birth asphyxia and if maternal dietary creatine supplement