Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Z. Hošťálek"'
Publikováno v:
Folia microbiologica. 36(5)
The surface layer, considered to be glycocalyx according to electron-microscopic observations, was separated from a low-production strain of Streptomyces aureofaciens by solubilization with urea and subsequent sonication. The isolation procedure was
Publikováno v:
Biotechnology advances. 8(1)
Biosynthesis of chlortetracycline is localized differently under low- and high-production conditions (standard low-production strain and its high-production variant). The experimental evidence was based on the assay of anhydrotetracycline oxygenase i
Publikováno v:
Transactions of the British Mycological Society. 62:377-389
Comparisons between submerged batch and chemostat fermentations of Gibberellafujikuroi show that major features of batch culture development relate directly to the degree of limiting substrate depletion and the corresponding growth rate. So-called se
Publikováno v:
Folia Microbiologica. 27:153-158
ATP diphosphohydrolase activity and inorganic pyrophosphatase reached two maxima during cultivation of the low- and high-producing variant of Streptomyces aureofaciens under conditions of phosphate limitation, i.e. after 30 and 70 h of cultivation. I
Effect of tetracycline derivatives and some cations on the activity of anhydrotetracycline oxygenase
Publikováno v:
Biotechnology Letters. 5:537-542
Anhydrotetracycline oxygenase was partially purified on a Sephadex G-25 column and DEAE-cellulose. The purified enzyme was inhibited by tetracycline derivatives added to the reaction mixture. Certain concentrations of calcium and magnesium ions stimu
Autor:
J. Neužil, Z. Hošťálek
Publikováno v:
Folia Microbiologica. 31:402-421
Enzymes participating in the biosynthesis of macrolide antibiotics are reviewed. Enzyme activities are known to play a pivotal role in the formation of biologically active compounds. Hence it is essential to understand these enzymes, their properties
Publikováno v:
Folia Microbiologica. 23:249-254
When improving Streptomyces coeruleorubidus JA 10092, a producer of antibiotics of the daunomycinone complex, the most active variants were found among isolates of morphological types bld-1 (with a suppressed production of the aerial mycelium on orga
Publikováno v:
Folia Microbiologica. 21:131-138
The activity of ATP-glucokinase and of polyphosphate glucokinase was examined during growth of the actinomycete Streptomyces aureofaciens 8425 under conditions of intense chlortetracycline (CTC) synthesis. ATP-glucokinase was active in the strain onl
Publikováno v:
Folia Microbiologica. 20:137-141
The process of isolation and purification of malate dehydrogenase (decarboxylating) (EC 1.1.1.40) from the mycelium of the actinomycete Streptomyces aureofaciens has been worked out. The enzyme was purified 35 fold. The kinetic characters of the puri
Publikováno v:
Folia Microbiologica. 24:128-135
Cosynthesis of anthracycline compounds was followed in five phenotypic groups of mutants ofStreptomyces coeruleorubidus (A - E), blocked in the biosynthesis of the daunomycine complex, and in two mutant types ofStreptomyces galilaeus (F, G) blooked i