Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Z. HASNAIN"'
Publikováno v:
Planta Daninha, Vol 38 (2020)
ABSTRACT: The study aimed to highlight the impact of naphthalene acetic acid (NAA) and irrigation regimes on the productivity of coarse rice under agro-ecological conditions of Dera Ismail Khan, Pakistan. The experiment was comprised of two factors w
Externí odkaz:
https://doaj.org/article/b74fb8c7ac9f412fa13b56e268088ec2
Autor:
Haressh Sajiir, Sahar Keshvari, Kuan Yau Wong, Danielle J. Borg, Frederik J. Steyn, Christian Fercher, Karin Taylor, Breten Taylor, Ross T. Barnard, Alexandra Müller, Md Moniruzzaman, Gregory Miller, Ran Wang, Amelia Fotheringham, Veronika Schreiber, Yong Hua Sheng, Janelle Louise Hancock, Dorothy Loo, Lucy Burr, Tony Huynh, Jack Lockett, Grant A. Ramm, Graeme A. Macdonald, Johannes B. Prins, Michael A. McGuckin, Sumaira Z. Hasnain
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Metabolic dysfunction-associated steatohepatitis (MASH) is the most prevalent cause of liver disease worldwide, with a single approved therapeutic. Previous research has shown that interleukin-22 (IL-22) can suppress β-cell stress, reduce l
Externí odkaz:
https://doaj.org/article/5c697ee738e34e89bcba2d1629c34f97
Autor:
Haressh Sajiir, Kuan Yau Wong, Alexandra Müller, Sahar Keshvari, Lucy Burr, Elena Aiello, Teresa Mezza, Andrea Giaccari, Guido Sebastiani, Francesco Dotta, Grant A. Ramm, Graeme A. Macdonald, Michael A. McGuckin, Johannes B. Prins, Sumaira Z. Hasnain
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The IL-22RA1 receptor is highly expressed in the pancreas, and exogenous IL-22 has been shown to reduce endoplasmic reticulum and oxidative stress in human pancreatic islets and promote secretion of high-quality insulin from beta-cells. Howe
Externí odkaz:
https://doaj.org/article/2dd7271812bb4bb1928d16716fbb7ba1
Autor:
Nguyen Thi Khanh Nhu, M. Arifur Rahman, Kelvin G. K. Goh, Seung Jae Kim, Minh-Duy Phan, Kate M. Peters, Laura Alvarez-Fraga, Steven J. Hancock, Chitra Ravi, Timothy J. Kidd, Matthew J. Sullivan, Katharine M. Irvine, Scott A. Beatson, Matthew J. Sweet, Adam D. Irwin, Jana Vukovic, Glen C. Ulett, Sumaira Z. Hasnain, Mark A. Schembri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bacteria adapt to selective pressure in their immediate environment in multiple ways. One mechanism involves the acquisition of independent mutations that disable or modify a key pathway, providing a signature of adaptation via convergent ev
Externí odkaz:
https://doaj.org/article/0c835c379e9d49008c3aba49b38fd4c2
Autor:
Michael A. McGuckin, Julie M. Davies, Pascal Felgner, Kuan Yau Wong, Rabina Giri, Yaowu He, Md Moniruzzaman, Thomas Kryza, Haressh Sajiir, John D. Hooper, Timothy H. Florin, Jakob Begun, Abderrahim Oussalah, Sumaira Z. Hasnain, Michael Hensel, Yong H. Sheng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 985-1009 (2023)
Background & Aims: MUC13 cell surface mucin is highly expressed on the mucosal surface throughout the intestine, yet its role against bacterial infection is unknown. We investigated how MUC13 impacts Salmonella typhimurium (S Tm) infection and elucid
Externí odkaz:
https://doaj.org/article/f2c1a11738f14b40a127bcac80dbb8db
Autor:
Yong Hua Sheng, Sumaira Z. Hasnain
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The mucosal surfaces that form the boundary between the external environment and the underlying tissue are protected by a mucus barrier. Mucin glycoproteins, both secreted and cell surface mucins, are the major components of the barrier. They can exc
Externí odkaz:
https://doaj.org/article/e4034aeb622246f4b2abdc53a28f91ad
Autor:
Yong H. Sheng, Garrett Z. Ng, Kim M. Summers, Alison L. Every, Gareth Price, Sumaira Z. Hasnain, Philip Sutton, Michael A. McGuckin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The cell surface mucin MUC1 is an important host factor limiting Helicobacter pylori (H. pylori) pathogenesis in both humans and mice by providing a protective barrier and modulating mucosal epithelial and leukocyte responses. The aim of this study w
Externí odkaz:
https://doaj.org/article/47d1f7e12af64ac189f947b5f73d3067
Autor:
Katina D Hulme, Limin Yan, Rebecca J Marshall, Conor J Bloxham, Kyle R Upton, Sumaira Z Hasnain, Helle Bielefeldt-Ohmann, Zhixuan Loh, Katharina Ronacher, Keng Yih Chew, Linda A Gallo, Kirsty R Short
Publikováno v:
eLife, Vol 9 (2020)
Diabetes mellitus is a known susceptibility factor for severe influenza virus infections. However, the mechanisms that underlie this susceptibility remain incompletely understood. Here, the effects of high glucose levels on influenza severity were in
Externí odkaz:
https://doaj.org/article/c77fdcadf032456989548c4375914ffe
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