Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Z. Eyal"'
Autor:
Giuseppe Cimicata, Analia V. Ezernitchi, Moti Baum, Y. Halfon, Elinor Breiner-Goldstein, Anat Bashan, Ella Zimmerman, Jennifer J. Schmidt, Donna Matzov, Lea Valinsky, Assaf Rokney, Haim Rozenberg, Andrew N. Lowell, Yojiro Anzai, Z. Eyal, David H. Sherman, Ada Yonath
Publikováno v:
'Nucleic Acids Research ', vol: 49, pages: 9560-9573 (2021)
Nucleic Acids Research
Nucleic Acids Research
Macrolides have been effective clinical antibiotics for over 70 years. They inhibit protein biosynthesis in bacterial pathogens by narrowing the nascent protein exit tunnel in the ribosome. The macrolide class of natural products consist of a macrola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb404168c2d0490ab77240bc68f342a
https://doi.org/10.1093/nar/gkab684
https://doi.org/10.1093/nar/gkab684
Autor:
Leilah Krounbi, Lior Aram, Assaf Gal, Z. Eyal, Eyal Shimoni, Konrad R. Hedderick, Lara A. Estroff
Publikováno v:
Chemistry of Materials. 33:3534-3542
Many organisms orchestrate the controlled precipitation of minerals. This physiological process takes place at ambient conditions, using soluble ions as building blocks. A widespread strategy for s...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3beea2f5bc2590c37513e1075cf252a9
https://doi.org/10.1021/acs.chemmater.0c04668
https://doi.org/10.1021/acs.chemmater.0c04668
Akademický článek
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Akademický článek
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Autor:
Haim Rozenberg, Ella Zimmerman, Z. Eyal, Donna Matzov, Anat Bashan, Ada Yonath, Micha Fridman, Miri Krupkin, Y. Halfon, Moran Shalev-Benami, Raphael I. Benhamou
Publikováno v:
'Nucleic Acids Research ', vol: 45, pages: 10284-10292 (2017)
Nucleic Acids Research
Nucleic Acids Research
Antimicrobial resistance within a wide range of pathogenic bacteria is an increasingly serious threat to global public health. Among these pathogenic bacteria are the highly resistant, versatile and possibly aggressive bacteria, Staphylococcus aureus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb46d5bc34de105cb4d8e78add58d36
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:48142
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:48142
Autor:
Søren Molin, Ruggero La Rosa, Y. Halfon, Matthew J. Belousoff, Ada Yonath, Rocio Espinosa Portero, Donna Matzov, Z. Eyal, Anat Bashan, Helle Krogh Johansen, Alicia Jiménez-Fernández, Ella Zimmerman
Publikováno v:
Halfon, Y, Jimenez-Fernandez, A, La Rosa, R, Espinosa Portero, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S & Yonath, A 2019, ' Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 44, pp. 22275-22281 . https://doi.org/10.1073/pnas.1909831116
Halfon, Y, Jimenez-Fernandez, A, Rosa, R L, Portero, R E, Johansen, H K, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S & Yonath, A 2019, ' Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 44, pp. 22275-22281 . https://doi.org/10.1073/pnas.1909831116
Halfon, Y, Jimenez-Fernandez, A, Rosa, R L, Portero, R E, Johansen, H K, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S & Yonath, A 2019, ' Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 44, pp. 22275-22281 . https://doi.org/10.1073/pnas.1909831116
Resistance to antibiotics has become a major threat to modern medicine. The ribosome plays a fundamental role in cell vitality by the translation of the genetic code into proteins; hence, it is a major target for clinically useful antibiotics. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f402860f1092acdbc60a3ea74d4bc25
https://curis.ku.dk/portal/da/publications/structure-of-pseudomonas-aeruginosa-ribosomes-from-an-aminoglycosideresistant-clinical-isolate(73c170c3-597b-43bd-a60a-ecfd66248055).html
https://curis.ku.dk/portal/da/publications/structure-of-pseudomonas-aeruginosa-ribosomes-from-an-aminoglycosideresistant-clinical-isolate(73c170c3-597b-43bd-a60a-ecfd66248055).html
Autor:
Z. Eyal, A. Bashan, Y. Halfon, Hanne Ingmer, Ella Zimmerman, A. Yonath, Jette Kjeldgaard, Donna Matzov
Publikováno v:
Scientific Reports
Halfon, Y, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J S, Ingmer, H & Yonath, A 2019, ' Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant ', Scientific Reports, vol. 9, no. 1, 11460 . https://doi.org/10.1038/s41598-019-48019-1
'Scientific Reports ', vol: 9, pages: 11460-1-11460-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Halfon, Y, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H & Yonath, A 2019, ' Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant ', Scientific Reports, vol. 9, no. 1, 11460 . https://doi.org/10.1038/s41598-019-48019-1
Halfon, Y, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J S, Ingmer, H & Yonath, A 2019, ' Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant ', Scientific Reports, vol. 9, no. 1, 11460 . https://doi.org/10.1038/s41598-019-48019-1
'Scientific Reports ', vol: 9, pages: 11460-1-11460-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Halfon, Y, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H & Yonath, A 2019, ' Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant ', Scientific Reports, vol. 9, no. 1, 11460 . https://doi.org/10.1038/s41598-019-48019-1
The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c57286abc7149df4952f5d9f833600
http://europepmc.org/articles/PMC6685948
http://europepmc.org/articles/PMC6685948
Autor:
Miri Krupkin, Z. Eyal, Haim Rozenberg, Ella Zimmerman, Anat Bashan, Donna Matzov, Ada Yonath, Itai Wekselman, Yael Diskin Posner
Publikováno v:
'Proceedings of the National Academy of Sciences of the USA ', vol: 113, pages: E6796-E6805 (2016)
Two structurally unique ribosomal antibiotics belonging to the orthosomycin family, avilamycin and evernimicin, possess activity against Enterococci, Staphylococci, and Streptococci, and other Gram-positive bacteria. Here, we describe the high-resolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f72acdd51cac24711814ea71bea2c02
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:45657
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:45657
Autor:
Anat Bashan, Ella Zimmerman, Donna Matzov, Z. Eyal, Susanne Paukner, Miri Krupkin, Itai Wekselman, Haim Rozenberg, Ada Yonath
Publikováno v:
'Proceedings of the National Academy of Sciences of the USA ', vol: 112, pages: E5805-E5814 (2015)
Significance Clinical use of the currently available antibiotics is severely compromised by the increasing resistance to them, acquired by the natural bacterial capability to manipulate their genomes. Many existing antibiotics target the fundamental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec7fe6868f243e6eb6b6d9562d0b435
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:42729
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:42729
Autor:
Matthew J. Belousoff, Shashi Bhushan, Donna Matzov, David R. Cameron, Trevor Lithgow, Anat Bashan, Z. Eyal, Tofayel Ahmed, Mazdak Radjainia, Ada Yonath, Satabdi Mishra, Anton Y. Peleg, Ella Zimmerman, Hans Elmlund, Rebecca S. Bamert
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
mBio, Vol 8, Iss 3, p e00395-17 (2017)
mBio, Vol 8, Iss 3, p e00395-17 (2017)
An unorthodox, surprising mechanism of resistance to the antibiotic linezolid was revealed by cryo-electron microscopy (cryo-EM) in the 70S ribosomes from a clinical isolate of Staphylococcus aureus . This high-resolution structural information demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2cb5594cab1d1a51ea58dc58320dc6
https://journals.asm.org/doi/10.1128/mBio.00395-17
https://journals.asm.org/doi/10.1128/mBio.00395-17