Zobrazeno 1 - 10
of 570
pro vyhledávání: '"Z-disc"'
Autor:
Matthias Petersen, Nesrin Schmiedel, Franziska Dierck, Susanne Hille, Anca Remes, Frauke Senger, Inga Schmidt, Renate Lüllmann-Rauch, Oliver J. Müller, Derk Frank, Ashraf Y. Rangrez, Norbert Frey, Christian Kuhn
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Despite the identification of numerous molecular pathways modulating cardiac hypertrophy its pathogenesis is not completely understood. In this study we define an unexpected role for Fibin (“fin bud initiation factor homolog”) in cardiomyocyte hy
Externí odkaz:
https://doaj.org/article/6a575afc00444393a65dd76ec25bfb68
Autor:
Michelle Rodriguez Garcia, Jeffrey Schmeckpeper, Maicon Landim-Vieira, Isabella Leite Coscarella, Xuan Fang, Weikang Ma, Payton A. Spran, Shengyao Yuan, Lin Qi, Aida Rahimi Kahmini, M. Benjamin Shoemaker, James B. Atkinson, Peter M. Kekenes-Huskey, Thomas C. Irving, Prescott Bryant Chase, Björn C. Knollmann, Jose Renato Pinto
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14572 (2023)
The ACTN2 gene encodes α-actinin 2, located in the Z-disc of the sarcomeres in striated muscle. In this study, we sought to investigate the effects of an ACTN2 missense variant of unknown significance (p.A868T) on cardiac muscle structure and functi
Externí odkaz:
https://doaj.org/article/5f43ec315b34474db0d9718fcffd7e19
Autor:
Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here
Externí odkaz:
https://doaj.org/article/cc6a0c4d5c4f4d3485748c72de4d581d
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Myofibrillar myopathy in humans causes protein aggregation, degeneration, and weakness of skeletal muscle. In horses, myofibrillar myopathy is a late-onset disease of unknown origin characterized by poor performance, atrophy, myof
Externí odkaz:
https://doaj.org/article/812ec08607e941d0a0e4c16f80695c93
Akademický článek
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Autor:
Dominik Müller, Sören Donath, Emanuel Georg Brückner, Santoshi Biswanath Devadas, Fiene Daniel, Lara Gentemann, Robert Zweigerdt, Alexander Heisterkamp, Stefan Michael Klaus Kalies
Publikováno v:
Bioengineering, Vol 8, Iss 12, p 213 (2021)
The proper function of cardiomyocytes (CMs) is highly related to the Z-disc, which has a pivotal role in orchestrating the sarcomeric cytoskeletal function. To better understand Z-disc related cardiomyopathies, novel models of Z-disc damage have to b
Externí odkaz:
https://doaj.org/article/e03b17152f64491eae25a518ec678924
Autor:
Weins, Astrid, Schwarz, Karin, Faul, Christian, Barisoni, Laura, Linke, Wolfgang A., Mundel, Peter
Publikováno v:
The Journal of Cell Biology, 2001 Oct . 155(3), 393-403.
Externí odkaz:
https://www.jstor.org/stable/1620636
Akademický článek
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Autor:
Wiesner, Sebastian, Salmikangas, Paula, Auerbach, Daniel, Himmel, Mirko, Kempa, Stefan, Hayeß, Katrin, Pacholsky, Dirk, Taivainen, Anu, Schröder, Rolf, Carpén, Olli, Fürst, Dieter O.
Publikováno v:
The Journal of Cell Biology, 2000 Oct . 151(2), 235-247.
Externí odkaz:
https://www.jstor.org/stable/1620183
Publikováno v:
The Journal of Cell Biology, 2000 Jan 01. 148(1), 101-114.
Externí odkaz:
https://www.jstor.org/stable/1619671